메뉴 건너뛰기




Volumn 123, Issue 23, 2010, Pages 4076-4084

REGγ modulates p53 activity by regulating its cellular localization

Author keywords

Cancer; Monoubiquitylation; p53; REG

Indexed keywords

PROTEASOME; PROTEIN MDM2; PROTEIN P53; REG GAMMA PROTEIN; UNCLASSIFIED DRUG; AUTOANTIGEN; KI ANTIGEN;

EID: 78649728761     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.067405     Document Type: Article
Times cited : (68)

References (28)
  • 2
    • 34447523329 scopus 로고    scopus 로고
    • Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors
    • Boutet, S. C., Disatnik, M. H., Chan, L. S., Iori, K. and Rando, T. A. (2007). Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. Cell 130, 349-362.
    • (2007) Cell , vol.130 , pp. 349-362
    • Boutet, S.C.1    Disatnik, M.H.2    Chan, L.S.3    Iori, K.4    Rando, T.A.5
  • 3
    • 31544457877 scopus 로고    scopus 로고
    • p53 ubiquitination: Mdm2 and beyond
    • Brooks, C. L. and Gu, W. (2006). p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21, 307-315.
    • (2006) Mol. Cell , vol.21 , pp. 307-315
    • Brooks, C.L.1    Gu, W.2
  • 4
    • 34047103990 scopus 로고    scopus 로고
    • C-terminal modifications regulate MDM2 dissociation and nuclear export of p53
    • Carter, S., Bischof, O., Dejean, A. and Vousden, K. H. (2007). C-terminal modifications regulate MDM2 dissociation and nuclear export of p53. Nat. Cell Biol. 9, 428-435.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 428-435
    • Carter, S.1    Bischof, O.2    Dejean, A.3    Vousden, K.H.4
  • 5
    • 34250342888 scopus 로고    scopus 로고
    • Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome
    • Chen, X., Barton, L. F., Chi, Y., Clurman, B. E. and Roberts, J. M. (2007). Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Mol. Cell 26, 843-852.
    • (2007) Mol. Cell , vol.26 , pp. 843-852
    • Chen, X.1    Barton, L.F.2    Chi, Y.3    Clurman, B.E.4    Roberts, J.M.5
  • 6
    • 0031724593 scopus 로고    scopus 로고
    • Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
    • Freedman, D. A. and Levine, A. J. (1998). Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol. Cell. Biol. 18, 7288-7293.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7288-7293
    • Freedman, D.A.1    Levine, A.J.2
  • 7
    • 33745713432 scopus 로고    scopus 로고
    • p53 and metabolism: Inside the TIGAR
    • Green, D. R. and Chipuk, J. E. (2006). p53 and metabolism: Inside the TIGAR. Cell 126, 30-32.
    • (2006) Cell , vol.126 , pp. 30-32
    • Green, D.R.1    Chipuk, J.E.2
  • 8
    • 2442494895 scopus 로고    scopus 로고
    • The common and distinct target genes of the p53 family transcription factors
    • Harms, K., Nozell, S. and Chen, X. (2004). The common and distinct target genes of the p53 family transcription factors. Cell. Mol. Life Sci. 61, 822-842.
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 822-842
    • Harms, K.1    Nozell, S.2    Chen, X.3
  • 9
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt, Y., Maya, R., Kazaz, A. and Oren, M. (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 10
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda, R., Tanaka, H. and Yasuda, H. (1997). Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420, 25-27.
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 11
    • 33644990074 scopus 로고    scopus 로고
    • Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking
    • Kawaguchi, Y., Ito, A., Appella, E. and Yao, T. (2006). Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking. J. Biol. Chem. 281, 1394-1400.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1394-1400
    • Kawaguchi, Y.1    Ito, A.2    Appella, E.3    Yao, T.4
  • 12
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat, M. H., Jones, S. N. and Vousden, K. H. (1997). Regulation of p53 stability by Mdm2. Nature 387, 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 14
    • 0348134742 scopus 로고    scopus 로고
    • Monoversus polyubiquitination: Differential control of p53 fate by Mdm2
    • Li, M., Brooks, C. L., Wu-Baer, F., Chen, D., Baer, R. and Gu, W. (2003). Monoversus polyubiquitination: differential control of p53 fate by Mdm2. Science 302, 1972-1975.
    • (2003) Science , vol.302 , pp. 1972-1975
    • Li, M.1    Brooks, C.L.2    Wu-Baer, F.3    Chen, D.4    Baer, R.5    Gu, W.6
  • 15
    • 31044449824 scopus 로고    scopus 로고
    • The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome
    • Li, X., Lonard, D. M., Jung, S. Y., Malovannaya, A., Feng, Q., Qin, J., Tsai, S. Y., Tsai, M. J. and O'Malley, B. W. (2006). The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell 124, 381-392.
    • (2006) Cell , vol.124 , pp. 381-392
    • Li, X.1    Lonard, D.M.2    Jung, S.Y.3    Malovannaya, A.4    Feng, Q.5    Qin, J.6    Tsai, S.Y.7    Tsai, M.J.8    O'Malley, B.W.9
  • 16
    • 34250339984 scopus 로고    scopus 로고
    • Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway
    • Li, X., Amazit, L., Long, W., Lonard, D. M., Monaco, J. J. and O'Malley, B. W. (2007). Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol. Cell 26, 831-842.
    • (2007) Mol. Cell , vol.26 , pp. 831-842
    • Li, X.1    Amazit, L.2    Long, W.3    Lonard, D.M.4    Monaco, J.J.5    O'Malley, B.W.6
  • 18
    • 58149115206 scopus 로고    scopus 로고
    • REGgamma, a proteasome activator and beyond?
    • Mao, I., Liu, J., Li, X. and Luo, H. (2008). REGgamma, a proteasome activator and beyond? Cell. Mol. Life Sci. 65, 3971-3980.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3971-3980
    • Mao, I.1    Liu, J.2    Li, X.3    Luo, H.4
  • 20
    • 4143070471 scopus 로고    scopus 로고
    • Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells
    • Nishizaki, M., Sasaki, J., Fang, B., Atkinson, E. N., Minna, J. D., Roth, J. A. and Ji, L. (2004). Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells. Cancer Res. 64, 5745-5752.
    • (2004) Cancer Res. , vol.64 , pp. 5745-5752
    • Nishizaki, M.1    Sasaki, J.2    Fang, B.3    Atkinson, E.N.4    Minna, J.D.5    Roth, J.A.6    Ji, L.7
  • 22
    • 0033767235 scopus 로고    scopus 로고
    • Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome- mediated degradation
    • Rodriguez, M. S., Desterro, J. M., Lain, S., Lane, D. P. and Hay, R. T. (2000). Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome- mediated degradation. Mol. Cell. Biol. 20, 8458-8467.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8458-8467
    • Rodriguez, M.S.1    Desterro, J.M.2    Lain, S.3    Lane, D.P.4    Hay, R.T.5
  • 23
    • 33751408022 scopus 로고    scopus 로고
    • Identification of PSME3 as a novel serum tumor marker for colorectal cancer by combining two-dimensional polyacrylamide gel electrophoresis with a strictly mass spectrometry-based approach for data analysis
    • Roessler, M., Rollinger, W., Mantovani-Endl, L., Hagmann, M. L., Palme, S., Berndt, P., Engel, A. M., Pfeffer, M., Karl, J., Bodenmuller, H. et al. (2006). Identification of PSME3 as a novel serum tumor marker for colorectal cancer by combining two-dimensional polyacrylamide gel electrophoresis with a strictly mass spectrometry-based approach for data analysis. Mol. Cell Proteomics 5, 2092-2101.
    • (2006) Mol. Cell Proteomics , vol.5 , pp. 2092-2101
    • Roessler, M.1    Rollinger, W.2    Mantovani-Endl, L.3    Hagmann, M.L.4    Palme, S.5    Berndt, P.6    Engel, A.M.7    Pfeffer, M.8    Karl, J.9    Bodenmuller, H.10
  • 24
    • 0033559256 scopus 로고    scopus 로고
    • A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
    • Stommel, J. M., Marchenko, N. D., Jimenez, G. S., Moll, U. M., Hope, T. J. and Wahl, G. M. (1999). A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18, 1660-1672.
    • (1999) EMBO J. , vol.18 , pp. 1660-1672
    • Stommel, J.M.1    Marchenko, N.D.2    Jimenez, G.S.3    Moll, U.M.4    Hope, T.J.5    Wahl, G.M.6
  • 25
    • 33845270990 scopus 로고    scopus 로고
    • Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
    • Toledo, F. and Wahl, G. M. (2006). Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat. Rev. Cancer 6, 909-923.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 909-923
    • Toledo, F.1    Wahl, G.M.2
  • 27
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang, Y., Xiong, Y. and Yarbrough, W. G. (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92, 725-734.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 28
    • 40949117250 scopus 로고    scopus 로고
    • Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation
    • Zhang, Z. and Zhang, R. (2008). Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation. EMBO J. 27, 852-864.
    • (2008) EMBO J. , vol.27 , pp. 852-864
    • Zhang, Z.1    Zhang, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.