메뉴 건너뛰기




Volumn 11, Issue 11, 2010, Pages 1525-1534

Genetic polymorphisms in sex hormone metabolizing genes and drug response in women with epilepsy

Author keywords

CYP1A1; estradiol; estrogen metabolizing pathway; first line antiepileptic drugs; neuropsychiatric disorders

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CYTOCHROME P450 1A; ESTRADIOL; ESTROGEN; PHENOBARBITAL; PHENYTOIN; SEX HORMONE; VALPROIC ACID;

EID: 78649706984     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.10.120     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 33847032838 scopus 로고    scopus 로고
    • Acute effects of estrogen on neuronal physiology
    • Woolley CS: Acute effects of estrogen on neuronal physiology. Annu. Rev. Pharmacol. Toxicol. 47, 657-680 (2007).
    • (2007) Annu. Rev. Pharmacol. Toxicol. , vol.47 , pp. 657-680
    • Woolley, C.S.1
  • 2
    • 0033304765 scopus 로고    scopus 로고
    • Estrogen actions in the central nervous system
    • McEwen BS, Alves SE: Estrogen actions in the central nervous system. Endocr. Rev. 20, 279-307 (1999).
    • (1999) Endocr. Rev. , vol.20 , pp. 279-307
    • McEwen, B.S.1    Alves, S.E.2
  • 3
    • 20444408765 scopus 로고    scopus 로고
    • Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women
    • Lurie G, Maskarinec G, Kaaks R, Stanczyk FZ, Le Marchand L: Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women. Cancer Epidemiol. Biomarkers Prev. 14, 1521-1527 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , pp. 1521-1527
    • Lurie, G.1    Maskarinec, G.2    Kaaks, R.3    Stanczyk, F.Z.4    Le Marchand, L.5
  • 4
    • 0033213920 scopus 로고    scopus 로고
    • Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17 CYP1A1 and COMT: A multigenic study on cancer susceptibility
    • Huang CS, Chern HD, Chang KJ, Cheng CW, Hsu SM, Shen CY: Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Cancer Res. 59, 4870-4875 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 4870-4875
    • Huang, C.S.1    Chern, H.D.2    Chang, K.J.3    Cheng, C.W.4    Hsu, S.M.5    Shen, C.Y.6
  • 6
    • 0041429623 scopus 로고    scopus 로고
    • Seizure frequency is associated with age at menopause in women with epilepsy
    • Harden CL, Koppel BS, Herzog AG, Nikolov BG, Hauser WA: Seizure frequency is associated with age at menopause in women with epilepsy. Neurology 61, 451-455 (2003).
    • (2003) Neurology , vol.61 , pp. 451-455
    • Harden, C.L.1    Koppel, B.S.2    Herzog, A.G.3    Nikolov, B.G.4    Hauser, W.A.5
  • 7
    • 0017094587 scopus 로고
    • Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle
    • Backstrom T: Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. Acta Neuro. Scand. 54, 321-347 (1976).
    • (1976) Acta Neuro. Scand. , vol.54 , pp. 321-347
    • Backstrom, T.1
  • 8
    • 67349176702 scopus 로고    scopus 로고
    • The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy
    • Reddy DS: The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy. Epilepsy Res. 85, 1-30 (2009).
    • (2009) Epilepsy Res. , vol.85 , pp. 1-30
    • Reddy, D.S.1
  • 9
    • 62949147212 scopus 로고    scopus 로고
    • Hormonal therapies: Progesterone
    • Herzog AG: Hormonal therapies: progesterone. Neurotherapeutics 6, 383-391 (2009).
    • (2009) Neurotherapeutics , vol.6 , pp. 383-391
    • Herzog, A.G.1
  • 10
    • 4444315260 scopus 로고    scopus 로고
    • Frequency of catamenial seizure exacerbation in women with localization-related epilepsy
    • Herzog AG, Harden CL, Liporace J et al.: Frequency of catamenial seizure exacerbation in women with localization-related epilepsy. Ann. Neurol. 56, 431-434 (2004).
    • (2004) Ann. Neurol. , vol.56 , pp. 431-434
    • Herzog, A.G.1    Harden, C.L.2    Liporace, J.3
  • 11
    • 0027987251 scopus 로고
    • Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism
    • Woolley CS, McEwen BS: Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. J. Neurosci. 14, 7680-7687 (1994).
    • (1994) J. Neurosci. , vol.14 , pp. 7680-7687
    • Woolley, C.S.1    McEwen, B.S.2
  • 12
    • 30144446236 scopus 로고    scopus 로고
    • Estradiol attenuates the K+-induced increase in extracellular GABA in rat striatum
    • Hu M, Watson CJ, Kennedy RT, Becker JB: Estradiol attenuates the K+-induced increase in extracellular GABA in rat striatum. Synapse 59, 122-124 (2006).
    • (2006) Synapse , vol.59 , pp. 122-124
    • Hu, M.1    Watson, C.J.2    Kennedy, R.T.3    Becker, J.B.4
  • 13
    • 0036376094 scopus 로고    scopus 로고
    • Estrogen actions throughout the brain
    • McEwen B: Estrogen actions throughout the brain. Recent Prog. Horm. Res. 57, 357-384 (2002).
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 357-384
    • McEwen, B.1
  • 14
    • 33646865176 scopus 로고    scopus 로고
    • BDNF and epilepsy: A missing link
    • Scharfman HE: BDNF and epilepsy: a missing link- Epilepsy Curr. 5, 83-88 (2005).
    • (2005) Epilepsy Curr. , vol.5 , pp. 83-88
    • Scharfman, H.E.1
  • 15
    • 0034526350 scopus 로고    scopus 로고
    • Estradiol: A protective factor in the adult brain
    • Wise PM: Estradiol: a protective factor in the adult brain. J. Pediatr. Endocrinol. Metab. 13, 1425-1429 (2000).
    • (2000) J. Pediatr. Endocrinol. Metab. , vol.13 , pp. 1425-1429
    • Wise, P.M.1
  • 16
    • 0026471940 scopus 로고
    • Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus
    • Weiland NG: Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus. Endocrinology 131, 2697-2702 (1992).
    • (1992) Endocrinology , vol.131 , pp. 2697-2702
    • Weiland, N.G.1
  • 17
    • 59649091955 scopus 로고    scopus 로고
    • Estradiol facilitates the release of neuropeptide-Y to suppress hippocampus-dependent seizures
    • Ledoux VA : Estradiol facilitates the release of neuropeptide-Y to suppress hippocampus-dependent seizures. J. Neurosci. 29, 1457-1468 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 1457-1468
    • Ledoux, V.A.1
  • 18
    • 0031848636 scopus 로고    scopus 로고
    • Functional role of estrogen metabolism in target cells: Review and perspectives
    • Zhu BT, Conney AH: Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 19, 1-27 (1998).
    • (1998) Carcinogenesis , vol.19 , pp. 1-27
    • Zhu, B.T.1    Conney, A.H.2
  • 19
    • 0042315387 scopus 로고    scopus 로고
    • Characterization of the oxidative metabolites of 17b-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms
    • Lee AJ, Cai MX, Thomas PE, Conney AH, Zhu BT: Characterization of the oxidative metabolites of 17b-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms. Endocrinology 144, 3382-3398 (2003).
    • (2003) Endocrinology , vol.144 , pp. 3382-3398
    • Lee, A.J.1    Cai, M.X.2    Thomas, P.E.3    Conney, A.H.4    Zhu, B.T.5
  • 20
    • 0026582475 scopus 로고
    • 17 b-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: A comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA
    • Spink DC, Eugster HP, Lincoln DW et al.: 17 b-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA. Arch. Biochem. Biophys. 293, 342-348 (1992).
    • (1992) Arch. Biochem. Biophys. , vol.293 , pp. 342-348
    • Spink, D.C.1    Eugster, H.P.2    Lincoln, D.W.3
  • 22
    • 39149106106 scopus 로고    scopus 로고
    • Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain
    • Dutheil F, Beaune P, Loriot MA: Xenobiotic metabolizing enzymes in the central nervous system: contribution of cytochrome P450 enzymes in normal and pathological human brain. Biochimie 90, 426-436 (2008).
    • (2008) Biochimie , vol.90 , pp. 426-436
    • Dutheil, F.1    Beaune, P.2    Loriot, M.A.3
  • 23
    • 84995856147 scopus 로고
    • Formation of 2- and 4-hydroxyestrogens by brain, pituitary, and liver of the human fetus
    • Ball P, Knuppen R: Formation of 2- and 4-hydroxyestrogens by brain, pituitary, and liver of the human fetus. J. Clin. Endocrinol. Metab. 47, 732-737 (1978).
    • (1978) J. Clin. Endocrinol. Metab. , vol.47 , pp. 732-737
    • Ball, P.1    Knuppen, R.2
  • 24
    • 0024307660 scopus 로고
    • Binding of 2-hydroxyestradiol and 4-hydroxyestradiol to estrogen receptors from human breast cancers
    • Van Aswegen CH, Purdy RH, Wittliff JL: Binding of 2-hydroxyestradiol and 4-hydroxyestradiol to estrogen receptors from human breast cancers. J. Steroid Biochem. 32, 485-492 (1989).
    • (1989) J. Steroid Biochem. , vol.32 , pp. 485-492
    • Van Aswegen, C.1    Purdy, R.H.2    Wittliff, J.L.3
  • 25
    • 0343178292 scopus 로고
    • Covalent binding of the endogenous estrogen 16 a-hydroxyestrone to estradiol receptor in human breast cancer cells: Characterization and intranuclear localization
    • Swaneck GE, Fishman J: Covalent binding of the endogenous estrogen 16 a-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization. Proc. Natl Acad. Sci. USA 85, 7831-7835 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 7831-7835
    • Swaneck, G.E.1    Fishman, J.2
  • 27
    • 0025099288 scopus 로고
    • The O-methylation of 4-hydroxyestradiol is inhibited by 2-hydroxyestradiol: Implications for estrogen-induced carcinogenesis
    • Roy D, Weisz J, Liehr JG: The O-methylation of 4-hydroxyestradiol is inhibited by 2-hydroxyestradiol: implications for estrogen-induced carcinogenesis. Carcinogenesis 11, 459-462 (1990).
    • (1990) Carcinogenesis , vol.11 , pp. 459-462
    • Roy, D.1    Weisz, J.2    Liehr, J.G.3
  • 28
    • 0024317220 scopus 로고
    • Proposal for revised classifcation of epilepsies and epileptic syndromes
    • Commission on Classifcation and Terminology of the International League Against Epilepsy
    • Proposal for revised classifcation of epilepsies and epileptic syndromes: Commission on Classifcation and Terminology of the International League Against Epilepsy. Epilepsia 30(4), 389-399 (1989).
    • (1989) Epilepsia , vol.30 , Issue.4 , pp. 389-399
  • 29
    • 77955847469 scopus 로고    scopus 로고
    • Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients
    • Grover S, Bala K, Sharma S et al.: Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. Biochimie. 92(9), 1207-1212 (2010).
    • (2010) Biochimie. , vol.92 , Issue.9 , pp. 1207-1212
    • Grover, S.1    Bala, K.2    Sharma, S.3
  • 30
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16, 1215 (1988).
    • (1988) Nucleic Acids Res. , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 31
    • 0033358548 scopus 로고    scopus 로고
    • Use of unlinked genetic markers to detect population stratifcation in association studies
    • Pritchard JK, Rosenberg NA: Use of unlinked genetic markers to detect population stratifcation in association studies. Am. J. Hum. Genet. 65, 220-228 (1999).
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 220-228
    • Pritchard, J.K.1    Rosenberg, N.A.2
  • 32
    • 4344633164 scopus 로고    scopus 로고
    • Association of polymorphisms and haplotypes in the elastin gene in Dutch patients with sporadic aneurysmal subarachnoid haemorrhage
    • Ruigrok YM, Seitz U, Wolterink S, Rinkel GJ, Wijmenga C, Urban Z: Association of polymorphisms and haplotypes in the elastin gene in Dutch patients with sporadic aneurysmal subarachnoid haemorrhage. Stroke 35, 2064-2068 (2004).
    • (2004) Stroke , vol.35 , pp. 2064-2068
    • Ruigrok, Y.M.1    Seitz, U.2    Wolterink, S.3    Rinkel, G.J.4    Wijmenga, C.5    Urban, Z.6
  • 33
    • 1842859051 scopus 로고    scopus 로고
    • Power and sample size calculations for case-control genetic association tests when errors are present: Application to single nucleotide polymorphisms
    • Gordon D, Finch SJ, Nothnagel M, Ott J: Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms. Hum. Hered. 54, 22-33 (2002).
    • (2002) Hum. Hered. , vol.54 , pp. 22-33
    • Gordon, D.1    Finch, S.J.2    Nothnagel, M.3    Ott, J.4
  • 34
    • 0042629677 scopus 로고    scopus 로고
    • Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies
    • Gordon D, Levenstien MA, Finch SJ, Ott J: Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies. Pac. Symp. Biocomput. 490-501 (2003).
    • (2003) Pac. Symp. Biocomput. , pp. 490-501
    • Gordon, D.1    Levenstien, M.A.2    Finch, S.J.3    Ott, J.4
  • 35
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Ana lysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ: Haploview: ana lysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 36
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989 (2001).
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 37
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of Bayesian methods for haplotype reconstruction from population genotype data
    • Stephens M, Donnelly P: A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet. 73, 1162-1169 (2003).
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 38
    • 33747824819 scopus 로고    scopus 로고
    • PupaSuite: Fnding functional single nucleotide polymorphisms for large-scale genotyping purposes
    • Conde L, Vaquerizas JM, Dopazo H et al.: PupaSuite: fnding functional single nucleotide polymorphisms for large-scale genotyping purposes. Nucleic Acids Res. 34, W621-W625 (2006).
    • (2006) Nucleic Acids Res. , vol.34
    • Conde, L.1    Vaquerizas, J.M.2    Dopazo, H.3
  • 40
    • 33748702356 scopus 로고    scopus 로고
    • The infuence of gonadal hormones on neuronal excitability, seizures, and epilepsy in the female
    • Scharfman HE, MacLusky NJ: The infuence of gonadal hormones on neuronal excitability, seizures, and epilepsy in the female. Epilepsia 47, 1423-1440 (2006).
    • (2006) Epilepsia , vol.47 , pp. 1423-1440
    • Scharfman, H.E.1    MacLusky, N.J.2
  • 41
    • 33747892232 scopus 로고    scopus 로고
    • CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal
    • Sowers MR, Wilson AL, Kardia SR, Chu J, McConnell DS: CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal. Am. J. Med. 119, S44-S51 (2006).
    • (2006) Am. J. Med. , vol.119
    • Sowers, M.R.1    Wilson, A.L.2    Kardia, S.R.3    Chu, J.4    McConnell, D.S.5
  • 42
    • 77449091996 scopus 로고    scopus 로고
    • Sex steroid metabolism polymorphisms and mammographic density in pre- and early peri-menopausal women
    • Crandall CJ, Sehl ME, Crawford SL et al.: Sex steroid metabolism polymorphisms and mammographic density in pre- and early peri-menopausal women. Breast Cancer Res. 11, R51 (2009).
    • (2009) Breast Cancer Res. , vol.11
    • Crandall, C.J.1    Sehl, M.E.2    Crawford, S.L.3
  • 44
    • 33747893585 scopus 로고    scopus 로고
    • Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors
    • Crandall CJ, Crawford SL, Gold EB: Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors. Am. J. Med. 119, S52-S60 (2006).
    • (2006) Am. J. Med. , vol.119
    • Crandall, C.J.1    Crawford, S.L.2    Gold, E.B.3
  • 45
    • 16844372350 scopus 로고    scopus 로고
    • Association of CYP1A1 polymorphisms with differential metabolic activation of 17b-estradiol and estrone
    • Kisselev P, Schunck WH, Roots I, Schwarz D: Association of CYP1A1 polymorphisms with differential metabolic activation of 17b-estradiol and estrone. Cancer Res. 65, 2972-2978 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 2972-2978
    • Kisselev, P.1    Schunck, W.H.2    Roots, I.3    Schwarz, D.4
  • 46
    • 33845976322 scopus 로고    scopus 로고
    • Estrogens and epilepsy: Why are we so excited
    • Veliskova J: Estrogens and epilepsy: why are we so excited- Neuroscientist 13, 77-88 (2007).
    • (2007) Neuroscientist , vol.13 , pp. 77-88
    • Veliskova, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.