메뉴 건너뛰기




Volumn 29, Issue 1, 2010, Pages 34-44

Knockdown of the interleukin-6 receptor alpha chain of dendritic cell vaccines enhances the therapeutic potential against IL-6 producing tumors

Author keywords

Dendritic cell vaccine; IL 6 receptor; Knockdown

Indexed keywords

CANCER VACCINE; DENDRITIC CELL VACCINE; FAS LIGAND; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 6 RECEPTOR ALPHA; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 78649688852     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.10.027     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 50249144544 scopus 로고    scopus 로고
    • T-cell activation by dendritic cells in the lymph node: lessons from the movies
    • Bousso P. T-cell activation by dendritic cells in the lymph node: lessons from the movies. Nat Rev Immunol 2008, 8:675-684.
    • (2008) Nat Rev Immunol , vol.8 , pp. 675-684
    • Bousso, P.1
  • 2
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • Banchereau J., Palucka A.K. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005, 5:296-306.
    • (2005) Nat Rev Immunol , vol.5 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 3
    • 0037446966 scopus 로고    scopus 로고
    • Transforming growth factor beta inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines
    • Kobie J.J., Wu R.S., Kurt R.A., Lou S., Adelman M.K., Whitesell L.J., et al. Transforming growth factor beta inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines. Cancer Res 2003, 63:1860-1864.
    • (2003) Cancer Res , vol.63 , pp. 1860-1864
    • Kobie, J.J.1    Wu, R.S.2    Kurt, R.A.3    Lou, S.4    Adelman, M.K.5    Whitesell, L.J.6
  • 4
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 2004, 4:941-952.
    • (2004) Nat Rev Immunol , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 5
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 2005, 5:263-274.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 6
    • 71649110874 scopus 로고    scopus 로고
    • Immunomodulation by semi-mature dendritic cells: a novel role of Toll-like receptors and interleukin-6
    • Frick J.S., Grünebach F., Autenrieth I.B. Immunomodulation by semi-mature dendritic cells: a novel role of Toll-like receptors and interleukin-6. Int J Med Microbiol 2010, 300:19-24.
    • (2010) Int J Med Microbiol , vol.300 , pp. 19-24
    • Frick, J.S.1    Grünebach, F.2    Autenrieth, I.B.3
  • 7
    • 34848915783 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
    • Sharma M.D., Baban B., Chandler P., Hou D.Y., Singh N., Yagita H., et al. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest 2007, 117:2570-2582.
    • (2007) J Clin Invest , vol.117 , pp. 2570-2582
    • Sharma, M.D.1    Baban, B.2    Chandler, P.3    Hou, D.Y.4    Singh, N.5    Yagita, H.6
  • 8
    • 0034577943 scopus 로고    scopus 로고
    • IL-6 switches the differentiation of monocytes from dendritic cells to macrophages
    • Chomarat P., Banchereau J., Davoust J., Palucka A.K. IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Nat Immunol 2000, 1:510-514.
    • (2000) Nat Immunol , vol.1 , pp. 510-514
    • Chomarat, P.1    Banchereau, J.2    Davoust, J.3    Palucka, A.K.4
  • 9
    • 38449092979 scopus 로고    scopus 로고
    • IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells
    • Geisel J., Kahl F., Müller M., Wagner H., Kirschning C.J., Autenrieth I.B., et al. IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells. J Immunol 2007, 179:5811-5818.
    • (2007) J Immunol , vol.179 , pp. 5811-5818
    • Geisel, J.1    Kahl, F.2    Müller, M.3    Wagner, H.4    Kirschning, C.J.5    Autenrieth, I.B.6
  • 10
    • 9444287003 scopus 로고    scopus 로고
    • Novel immunosuppressive properties of interleukin-6 in dendritic cells: inhibition of NF-kappaB binding activity and CCR7 expression
    • Hegde S., Pahne J., Smola-Hess S. Novel immunosuppressive properties of interleukin-6 in dendritic cells: inhibition of NF-kappaB binding activity and CCR7 expression. FASEB J 2004, 18:1439-1441.
    • (2004) FASEB J , vol.18 , pp. 1439-1441
    • Hegde, S.1    Pahne, J.2    Smola-Hess, S.3
  • 11
    • 59649107188 scopus 로고    scopus 로고
    • Enhancement of dendritic cell-based vaccine potency by anti-apoptotic siRNAs targeting key pro-apoptotic proteins in cytotoxic CD8(+) T cell-mediated cell death
    • Kim J.H., Kang T.H., Noh K.H., Bae H.C., Kim S.H., Yoo Y.D., et al. Enhancement of dendritic cell-based vaccine potency by anti-apoptotic siRNAs targeting key pro-apoptotic proteins in cytotoxic CD8(+) T cell-mediated cell death. Immunol Lett 2009, 122:58-67.
    • (2009) Immunol Lett , vol.122 , pp. 58-67
    • Kim, J.H.1    Kang, T.H.2    Noh, K.H.3    Bae, H.C.4    Kim, S.H.5    Yoo, Y.D.6
  • 12
    • 41149117399 scopus 로고    scopus 로고
    • Development of an in vivo antibody-mediated killing (IVAK) model, a flow cytometric method to rapidly evaluate therapeutic antibodies
    • Guyre C.A., Gomes D., Smith K.A., Kaplan J.M., Perricone M.A. Development of an in vivo antibody-mediated killing (IVAK) model, a flow cytometric method to rapidly evaluate therapeutic antibodies. J Immunol Methods 2008, 333:51-60.
    • (2008) J Immunol Methods , vol.333 , pp. 51-60
    • Guyre, C.A.1    Gomes, D.2    Smith, K.A.3    Kaplan, J.M.4    Perricone, M.A.5
  • 13
    • 2942592160 scopus 로고    scopus 로고
    • Generation of tumor-specific cytotoxic T lymphocyte and prolongation of the survival of tumor-bearing mice using interleukin-18-secreting fibroblasts loaded with an epitope peptide
    • Chung S.W., Cohen E.P., Kim T.S. Generation of tumor-specific cytotoxic T lymphocyte and prolongation of the survival of tumor-bearing mice using interleukin-18-secreting fibroblasts loaded with an epitope peptide. Vaccine 2004, 22:2547-2557.
    • (2004) Vaccine , vol.22 , pp. 2547-2557
    • Chung, S.W.1    Cohen, E.P.2    Kim, T.S.3
  • 14
    • 0041929457 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway is important for optimal tumor regression in a mouse model of CTL adoptive immunotherapy of experimental CMS4 lung metastases
    • Caldwell S.A., Ryan M.H., McDuffie E., Abrams S.I. The Fas/Fas ligand pathway is important for optimal tumor regression in a mouse model of CTL adoptive immunotherapy of experimental CMS4 lung metastases. J Immunol 2003, 171:2402-2412.
    • (2003) J Immunol , vol.171 , pp. 2402-2412
    • Caldwell, S.A.1    Ryan, M.H.2    McDuffie, E.3    Abrams, S.I.4
  • 15
    • 28244465238 scopus 로고    scopus 로고
    • Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes
    • Jackson S.S., Schmitz J.E., Kuroda M.J., McKay P.F., Sumida S.M., Martin K.L., et al. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology 2005, 116:443-453.
    • (2005) Immunology , vol.116 , pp. 443-453
    • Jackson, S.S.1    Schmitz, J.E.2    Kuroda, M.J.3    McKay, P.F.4    Sumida, S.M.5    Martin, K.L.6
  • 16
    • 33847351136 scopus 로고    scopus 로고
    • The JAK-STAT signaling pathway: input and output integration
    • Murray P.J. The JAK-STAT signaling pathway: input and output integration. J Immunol 2007, 178:2623-2629.
    • (2007) J Immunol , vol.178 , pp. 2623-2629
    • Murray, P.J.1
  • 17
    • 0038281345 scopus 로고    scopus 로고
    • Downstream effectors of oncogenic ras in multiple myeloma cells
    • Hu L., Shi Y., Hsu J.H., Gera J., Van Ness B., Lichtenstein A. Downstream effectors of oncogenic ras in multiple myeloma cells. Blood 2003, 101:3126-3135.
    • (2003) Blood , vol.101 , pp. 3126-3135
    • Hu, L.1    Shi, Y.2    Hsu, J.H.3    Gera, J.4    Van Ness, B.5    Lichtenstein, A.6
  • 18
    • 0347907720 scopus 로고    scopus 로고
    • PI3-K/Akt pathway contributes to IL-6-dependent growth of 7TD1 cells
    • Zhang J., Li Y., Shen B. PI3-K/Akt pathway contributes to IL-6-dependent growth of 7TD1 cells. Cancer Cell Int 2003, 3:1.
    • (2003) Cancer Cell Int , vol.3 , pp. 1
    • Zhang, J.1    Li, Y.2    Shen, B.3
  • 19
    • 77950690023 scopus 로고    scopus 로고
    • Interleukin-6 in bone metastasis and cancer progression
    • Ara T., Declerck Y.A. Interleukin-6 in bone metastasis and cancer progression. Eur J Cancer 2010, 46:1223-1231.
    • (2010) Eur J Cancer , vol.46 , pp. 1223-1231
    • Ara, T.1    Declerck, Y.A.2
  • 20
    • 77955725489 scopus 로고    scopus 로고
    • Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients
    • Deng L., Zhang H., Luan Y., Zhang J., Xing Q., Dong S., et al. Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. Clin Cancer Res 2010, 16:4105-4112.
    • (2010) Clin Cancer Res , vol.16 , pp. 4105-4112
    • Deng, L.1    Zhang, H.2    Luan, Y.3    Zhang, J.4    Xing, Q.5    Dong, S.6
  • 21
    • 70349423483 scopus 로고    scopus 로고
    • Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma
    • Sinicrope F.A., Rego R.L., Ansell S.M., Knutson K.L., Foster N.R., Sargent D.J. Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. Gastroenterology 2009, 137:1270-1279.
    • (2009) Gastroenterology , vol.137 , pp. 1270-1279
    • Sinicrope, F.A.1    Rego, R.L.2    Ansell, S.M.3    Knutson, K.L.4    Foster, N.R.5    Sargent, D.J.6
  • 22
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock D.J., Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003, 300:337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 23
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun J.C., Bevan M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003, 300:339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 24
    • 34648836563 scopus 로고    scopus 로고
    • Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination
    • Karbach J., Gnjatic S., Pauligk C., Bender A., Maeurer M., Schultze J.L., et al. Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination. Int J Cancer 2007, 121:2042-2048.
    • (2007) Int J Cancer , vol.121 , pp. 2042-2048
    • Karbach, J.1    Gnjatic, S.2    Pauligk, C.3    Bender, A.4    Maeurer, M.5    Schultze, J.L.6
  • 25
    • 34247156114 scopus 로고    scopus 로고
    • New peptide vaccine candidates for epithelial cancer patients with HLA-A3 supertype alleles
    • Matsueda S., Takedatsu H., Sasada T., Azuma K., Ishihara Y., Komohara Y., et al. New peptide vaccine candidates for epithelial cancer patients with HLA-A3 supertype alleles. J Immunother 2007, 30:274-281.
    • (2007) J Immunother , vol.30 , pp. 274-281
    • Matsueda, S.1    Takedatsu, H.2    Sasada, T.3    Azuma, K.4    Ishihara, Y.5    Komohara, Y.6
  • 26
    • 0028979830 scopus 로고
    • Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells
    • Mukherji B., Chakraborty N.G., Yamasaki S., Okino T., Yamase H., Sporn J.R., et al. Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells. Proc Natl Acad Sci USA 1995, 92:8078-8082.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8078-8082
    • Mukherji, B.1    Chakraborty, N.G.2    Yamasaki, S.3    Okino, T.4    Yamase, H.5    Sporn, J.R.6
  • 27
    • 59449103002 scopus 로고    scopus 로고
    • A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA
    • Yen M.C., Lin C.C., Chen Y.L., Huang S.S., Yang H.J., Chang C.P., et al. A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA. Clin Cancer Res 2009, 15:641-649.
    • (2009) Clin Cancer Res , vol.15 , pp. 641-649
    • Yen, M.C.1    Lin, C.C.2    Chen, Y.L.3    Huang, S.S.4    Yang, H.J.5    Chang, C.P.6
  • 28
    • 44749086937 scopus 로고    scopus 로고
    • Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma
    • Toomey D., Conroy H., Jarnicki A.G., Higgins S.C., Sutton C., Mills K.H. Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma. Vaccine 2008, 26:3540-3549.
    • (2008) Vaccine , vol.26 , pp. 3540-3549
    • Toomey, D.1    Conroy, H.2    Jarnicki, A.G.3    Higgins, S.C.4    Sutton, C.5    Mills, K.H.6
  • 29
    • 44249102834 scopus 로고    scopus 로고
    • The role of immunohistochemistry in medullomyoblastoma-a case series highlighting divergent differentiation
    • Sachdeva M.U., Vankalakunti M., Rangan A., Radotra B.D., Chhabra R., Vasishta R.K. The role of immunohistochemistry in medullomyoblastoma-a case series highlighting divergent differentiation. Diagn Pathol 2008, 3:18.
    • (2008) Diagn Pathol , vol.3 , pp. 18
    • Sachdeva, M.U.1    Vankalakunti, M.2    Rangan, A.3    Radotra, B.D.4    Chhabra, R.5    Vasishta, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.