Expression, localization, and regulation of the neuregulin receptor ErbB3 in mouse heart

Journal of Cellular Physiology

Volumn 226, Issue 2, 2011, Pages 450-455

  Campreciós, Genís ^a   Lorita, Jordi ^a   Pardina, Eva ^a   Peinado Onsurbe, Julia ^a   Soley, Maria ^a   Ramírez, Ignasi ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HEART HYPERTROPHY; HEART MUSCLE CELL; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; FEMALE; LIVER; MALE; MICE; MYOCARDIUM; NEUREGULINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; RNA, MESSENGER;

MUS;

EID: 78649650001     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22354     Document Type: Article

References (40)

1. Bersell K, Arab S, Haring B, Kuhn B. 2009. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138: 257-270.
2. Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X. 2009. Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins. Am J Physiol Heart Circ Physiol 297: H1974-H1983.
3. Bria E, Cuppone F, Milella M, Verma S, Carlini P, Nistico C, Vaccaro V, Rossi A, Tonini G, Cognetti F, Terzoli E. 2008. Trastuzumab cardiotoxicity: Biological hypotheses and clinical open issues. Expert Opin Biol Ther 8: 1963-1971.
4. Britsch S. 2007. The neuregulin-I/ErbB signaling system in development and disease. Adv Anat Embryol Cell Biol 190: 1-65.
5. Carley AN, Semeniuk LM, Shimoni Y, Aasum E, Larsen TS, Berger JP, Severson DL. 2004. Treatment of type 2 diabetic db/db mice with a novel PPARgamma agonist improves cardiac metabolism but not contractile function. Am J Physiol Endocrinol Metab 286: E449-E455.
6. Carver RS, Stevenson MC, Scheving LA, Russell WE. 2002. Diverse expression of ErbB receptor proteins during rat liver development and regeneration. Gastroenterology 123: 2017-2027.
7. Chung KY, Walker JW. 2007. Interaction and inhibitory cross-talk between endothelin and ErbB receptors in the adult heart. Mol Pharmacol 71: 1494-1502.
8. Cote GM, Miller TA, Lebrasseur NK, Kuramochi Y, Sawyer DB. 2005. Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro. Exp Cell Res 311: 135-146.
9. Couet J, Sargiacomo M, Lisanti MP. 1997. Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities. J Biol Chem 272: 30429-30438.
10. Crone SA, Zhao YY, Fan L, Gu Y, Minamisawa S, Liu Y, Peterson KL, Chen J, Kahn R, Condorelli G, Ross J, Jr., Chien KR, Lee KF. 2002. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 8: 459-465.
11. De Keulenaer GW, Doggen K, Lemmens K. 2010. The vulnerability of the heart as a pluricellular paracrine organ: Lessons from unexpected triggers of heart failure in targeted ErbB2 anticancer therapy. Circ Res 106: 35-46.
12. Erickson SL, O'Shea KS, Ghaboosi N, Loverro L, Frantz G, Bauer M, Lu LH, Moore MW. 1997. ErbB3 is required for normal cerebellar and cardiac development: A comparison with ErbB2-and heregulin-deficient mice. Development 124: 4999-5011.
13. Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB. 2003. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J Mol Cell Cardiol 35: 1473-1479.
14. Fuller SJ, Sivarajah K, Sugden PH. 2008. ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium. J Mol Cell Cardiol 44: 831-854.
15. Garcia-Rivello H, Taranda J, Said M, Cabeza-Meckert P, Vila-Petroff M, Scaglione J, Ghio S, Chen J, Lai C, Laguens RP, Lloyd KC, Hertig CM. 2005. Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle. Am J Physiol Heart Circ Physiol 289: H1153-H1160.
16. Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, Lemke G. 1995. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378: 390-394.
17. Kuramochi Y, Guo X, Sawyer DB. 2006. Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes. J Mol Cell Cardiol 41: 228-235.
18. Lebrasseur NK, Cote GM, Miller TA, Fielding RA, Sawyer DB. 2003. Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle. Am J Physiol Cell Physiol 284: C1149-C1155.
19. Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C. 1995. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 378: 394-398.
20. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408.
21. Lorita J, Camprecios G, Soley M, Ramirez I. 2009. ErbB receptors protect the perfused heart against injury induced by epinephrine combined with low-flow ischemia. Growth Factors 27: 203-213.
22. Meyer D, Birchmeier C. 1995. Multiple essential functions of neuregulin in development. Nature 378: 386-390.
23. Nicolino S, Panetto A, Raimondo S, Gambarotta G, Guzzini M, Fornaro M, Battiston B, Tos P, Geuna S, Perroteau I. 2009. Denervation and reinnervation of adult skeletal muscle modulate mRNA expression of neuregulin-1 and ErbB receptors. Microsurgery 29: 464-472.
24. Ozcelik C, Erdmann B, Pilz B, Wettschureck N, Britsch S, Hubner N, Chien KR, Birchmeier C, Garratt AN. 2002. Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci USA 99: 8880-8885.
25. Pareja M, Sanchez O, Lorita J, Soley M, Ramirez I. 2003. Activated epidermal growth factor receptor (ErbB1) protects the heart against stress-induced injury in mice. Am J Physiol Regul Integr Comp Physiol 285: R455-R462.
26. Pentassuglia L, Sawyer DB. 2009. The role of neuregulin-1beta/ErbB signaling in the heart. Exp Cell Res 315: 627-637.
27. Pentassuglia L, Graf M, Lane H, Kuramochi Y, Cote G, Timolati F, Sawyer DB, Zuppinger C, Suter TM. 2009. Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes. Exp Cell Res 315: 1302-1312.
28. Prigent SA, Lemoine NR, Hughes CM, Plowman GD, Selden C, Gullick WJ. 1992. Expression of the c-erbB-3 protein in normal human adult and fetal tissues. Oncogene 7: 1273-1278.
29. Rajagopalan V, Zucker IH, Jones JA, Carlson M, Ma YJ. 2008. Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction. Am J Physiol Heart Circ Physiol 295: H543-H554.
30. Rohrbach S, Yan X, Weinberg EO, Hasan F, Bartunek J, Marchionni MA, Lorell BH. 1999. Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors. Circulation 100: 407-412.
31. Rohrbach S, Niemann B, Silber RE, Holtz J. 2005. Neuregulin receptors erbB2 and erbB4 in failing human myocardium-Depressed expression and attenuated activation. Basic Res Cardiol 100: 240-249.
32. Russell KS, Stern DF, Polverini PJ, Bender JR. 1999. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. Am J Physiol 277: H2205-H2211.
33. Sawyer DB, Zuppinger C, Miller TA, Eppenberger HM, Suter TM. 2002. Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: Potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 105: 1551-1554.
34. Suarez E, Bach D, Cadefau J, Palacin M, Zorzano A, Guma A. 2001. A novel role of neuregulin in skeletal muscle. Neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells. J Biol Chem 276: 18257-18264.
35. Sundaresan S, Roberts PE, King KL, Sliwkowski MX, Mather JP. 1998. Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression. Endocrinology 139: 4756-4764.
36. Wen D, Peles E, Cupples R, Suggs SV, Bacus SS, Luo Y, Trail G, Hu S, Silbiger SM, Levy RB. 1992. Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell 69: 559-572.
37. Xu Y, Li X, Zhou M. 2009. Neuregulin-1/ErbB signaling: A druggable target for treating heart failure. Curr Opin Pharmacol 9: 214-219.
38. Zak B, Cohen J. 1961. Automatic analysis of tissue culture proteins with stable Folin reagents. Clin Chim Acta 6: 665-670.
39. Zhao YY, Sawyer DR, Baliga RR, Opel DJ, Han X, Marchionni MA, Kelly RA. 1998. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 273: 10261-10269.
40. Zhao YY, Feron O, Dessy C, Han X, Marchionni MA, Kelly RA. 1999. Neuregulin signaling in the heart. Dynamic targeting of erbB4 to caveolar microdomains in cardiac myocytes. Circ Res 84: 1380-1387.