Experimental investigation of ingavirin®antiviral activity against human parainfluenza virus

Antibiotiki i Khimioterapiya

Volumn 55, Issue 7-8, 2010, Pages 13-16

  Zarubaev, V V ^a   Krivitskaya, V Z ^a   Nebolsin, V E ^b   Kiselev, O I ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b Valenta Farm Co   (Russian Federation)

Author keywords

Antiviral activity; Cytoprotective action; Ingavirin*; Parainfluenza virus

Indexed keywords

AMIDE; ANTIVIRUS AGENT; DICARBOXYLIC ACID; IMIDAZOLE DERIVATIVE; PENTANEDIOIC ACID IMIDAZOLYL ETHANAMIDE; TETRAZOLIUM;

ANIMAL; ARTICLE; BRONCHUS; CELL LINE; CELL PROTECTION; CHEMISTRY; CYTOPATHOGENIC EFFECT; DRUG EFFECT; ENZYME IMMUNOASSAY; HUMAN; PARAMYXOVIRUS; PARAMYXOVIRUS INFECTION; PATHOLOGY; RESPIRATORY TRACT MUCOSA; VIROLOGY;

AMIDES; ANIMALS; ANTIVIRAL AGENTS; BRONCHI; CELL LINE; CYTOPATHOGENIC EFFECT, VIRAL; CYTOPROTECTION; DICARBOXYLIC ACIDS; HUMANS; IMIDAZOLES; IMMUNOENZYME TECHNIQUES; PARAMYXOVIRIDAE; PARAMYXOVIRIDAE INFECTIONS; RESPIRATORY MUCOSA; TETRAZOLIUM SALTS;

PARAINFLUENZA VIRUS;

EID: 78649627008     PISSN: 02352990     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Henrickson K. J. Parainfluenza viruses. Clin Microbiol Rev. 2003; 16: 242-264.
2. Abed Y., Bolvin G. Treatment of respiratory virus infections. Antiviral Res. 2006; 70: 2:1-16.
3. Alymova I. V., Taylor G., Takimoto T. et al. Efficacy of novel hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 against human parainfluenza viruses in vitro and in vivo. Antimicrob Agents Chemother 2004; 48:5:1495-502.
4. Saladino R., Ciambecchini U., Nencioni L., Palamara A. T. Recent advances in the chemistry of parainfluenza-1 (Sendai) virus inhibitors. Med Res Rev 2003; 23:4:427-455.
5. De Franceschi L., Fattovich G., Turrini F. et al. Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage. Hepatology 2000; 31:4:997-1004.
6. Prince G. A., Porter D. D. Treatment of parainfluenza virus type 3 bronchiolitis and pneumonia in a cotton rat model using topical antibody and glucocorticosteroid. J Infect Dis 1996; 173:3:598-608.
7. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.