Increased sensitivity of KRAS mutation detection by high-resolution melting analysis of COLD-PCR products

Human Mutation

Volumn 31, Issue 12, 2010, Pages 1366-1373

  Kristensen, Lasse S ^a   Daugaard, Iben L ^a   Christensen, Mariann ^b   Hamilton Dutoit, Stephen ^b   Hager, Henrik ^b   Hansen, Lise Lotte ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Cancer; COLD PCR; High resolution melting; HRM; HRMA; KRAS

Indexed keywords

K RAS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BLOOD ANALYSIS; COAMPLIFICATION AT LOWER DENATURATION TEMPERATURE POLYMERASE CHAIN REACTION; CODON; COLON ADENOCARCINOMA; CONTROLLED STUDY; DNA EXTRACTION; EXON; FOOD AND DRUG ADMINISTRATION; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; MELTING POINT; MUTANT; NUCLEOTIDE SEQUENCE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PSEUDOGENE; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

BASE SEQUENCE; CELL LINE; COLD TEMPERATURE; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; EXONS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID DENATURATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PSEUDOGENES; RAS PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 78649538649     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21358     Document Type: Article

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