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Volumn 148, Issue 1, 2010, Pages 101-105

Tumor therapy by gene regulation system responding to cellular signal

Author keywords

Gene therapy; Intracellular signal; Peptide; Phosphorylation; Protein kinase

Indexed keywords

CASPASES; CATIONIC PEPTIDES; CELLULAR SIGNALS; GANCICLOVIR; GENE COMPLEXES; GENE DELIVERY; GENE DELIVERY SYSTEMS; GENE REGULATIONS; HERPES SIMPLEX VIRUS; INTRACELLULAR SIGNALS; INTRAPERITONEALLY; NEGATIVE CONTROL; PEPTIDE SIDE CHAINS; PHOSPHORYLATION SITES; POLYACRY LAMIDE; POLYMERIC CARRIERS; PRODRUGS; PROTEIN KINASE; PROTEIN KINASE C; SERINE RESIDUES; THERAPEUTIC GENES; THYMIDINE KINASE; TRANS-GENES; TUMOR CELLS; TUMOR GENE THERAPY; TUMOR GROWTH; TUMOR THERAPY;

EID: 78649529322     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.08.017     Document Type: Article
Times cited : (13)

References (29)
  • 1
    • 33749072019 scopus 로고    scopus 로고
    • Nuclear signaling by receptor tyrosine kinases: the first robin of spring
    • Schlessinger J., Lemmon M.A. Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell 2006, 127:45-48.
    • (2006) Cell , vol.127 , pp. 45-48
    • Schlessinger, J.1    Lemmon, M.A.2
  • 2
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling in cancer
    • Normanno N., De Luca A., Bianco C. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 2006, 366:2-16.
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1    De Luca, A.2    Bianco, C.3
  • 3
    • 67749122122 scopus 로고    scopus 로고
    • Targeting PI3K signaling in cancer: opportunities, challenges and limitations
    • Engelman J.A. Targeting PI3K signaling in cancer: opportunities, challenges and limitations. Nat. Rev. Cancer 2009, 9:550-562.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 550-562
    • Engelman, J.A.1
  • 4
    • 1542619344 scopus 로고    scopus 로고
    • Protein kinase C isozymes as potential targets for anticancer therapy
    • Hofmann J. Protein kinase C isozymes as potential targets for anticancer therapy. Curr. Cancer Drug Targets 2004, 4:125-146.
    • (2004) Curr. Cancer Drug Targets , vol.4 , pp. 125-146
    • Hofmann, J.1
  • 5
    • 34250902930 scopus 로고    scopus 로고
    • Targeting the protein kinase C family: are we there yet?
    • Mackay H.J., Twelves C.J. Targeting the protein kinase C family: are we there yet?. Nat. Rev. Cancer 2007, 7:554-562.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 554-562
    • Mackay, H.J.1    Twelves, C.J.2
  • 6
    • 33644861034 scopus 로고    scopus 로고
    • Protein kinase Cα and e{open} small-molecule targeted therapeutics: a new roadmap to two holy grails in drug discovery?
    • O'Brian C.A., Chu F., Bornmann W.G., Maxwell D.S. Protein kinase Cα and e{open} small-molecule targeted therapeutics: a new roadmap to two holy grails in drug discovery?. Expert Rev. Anticancer Ther. 2006, 6:175-186.
    • (2006) Expert Rev. Anticancer Ther. , vol.6 , pp. 175-186
    • O'Brian, C.A.1    Chu, F.2    Bornmann, W.G.3    Maxwell, D.S.4
  • 8
    • 67650684000 scopus 로고    scopus 로고
    • Protein kinase Cα polymeric carrier: its application for gene delivery into human cancers
    • Tomiyama T., Kang J.H., Toita R., Niidome T., Katayama Y. Protein kinase Cα polymeric carrier: its application for gene delivery into human cancers. Cancer Sci. 2009, 100:1532-1536.
    • (2009) Cancer Sci. , vol.100 , pp. 1532-1536
    • Tomiyama, T.1    Kang, J.H.2    Toita, R.3    Niidome, T.4    Katayama, Y.5
  • 9
    • 69949137270 scopus 로고    scopus 로고
    • Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems
    • Toita R., Kang J.H., Kim J.H., Tomiyama T., Mori T., Niidome T., Jun B., Katayama Y. Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems. J. Control. Release 2009, 139:133-139.
    • (2009) J. Control. Release , vol.139 , pp. 133-139
    • Toita, R.1    Kang, J.H.2    Kim, J.H.3    Tomiyama, T.4    Mori, T.5    Niidome, T.6    Jun, B.7    Katayama, Y.8
  • 11
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I., Debatin K.M. Cellular stress response and apoptosis in cancer therapy. Blood 2001, 98:2603-2614.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.M.2
  • 12
    • 33845501864 scopus 로고    scopus 로고
    • Apotosome: a platform for the activation of initiator caspases
    • Bao Q., Shi Y. Apotosome: a platform for the activation of initiator caspases. Cell Death Differ. 2007, 14:56-65.
    • (2007) Cell Death Differ. , vol.14 , pp. 56-65
    • Bao, Q.1    Shi, Y.2
  • 13
    • 0037832252 scopus 로고    scopus 로고
    • Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/canciclovir system: fifteen years of application
    • Fillat C., Carrió M., Cascante A., Sangro B. Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/canciclovir system: fifteen years of application. Curr. Gene Ther. 2003, 3:13-26.
    • (2003) Curr. Gene Ther. , vol.3 , pp. 13-26
    • Fillat, C.1    Carrió, M.2    Cascante, A.3    Sangro, B.4
  • 14
    • 0036291075 scopus 로고    scopus 로고
    • Gene therapy of hepatocellular carcinoma and gastrointestinal tumors
    • Sangro B., Qian C., Schmitz V., Prieto J. Gene therapy of hepatocellular carcinoma and gastrointestinal tumors. Ann N.Y. Acad. Sci. 2002, 963:6-12.
    • (2002) Ann N.Y. Acad. Sci. , vol.963 , pp. 6-12
    • Sangro, B.1    Qian, C.2    Schmitz, V.3    Prieto, J.4
  • 15
    • 38749101958 scopus 로고    scopus 로고
    • Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy medicated by albumin-associated cationic liposomes
    • Faneca H., Faustino A., Pedroso de Lima M.C. Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy medicated by albumin-associated cationic liposomes. J. Control. Release 2008, 126:175-184.
    • (2008) J. Control. Release , vol.126 , pp. 175-184
    • Faneca, H.1    Faustino, A.2    Pedroso de Lima, M.C.3
  • 16
    • 0014202608 scopus 로고
    • A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization
    • LePecq J.B., Paoletti C. A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization. J. Mol. Biol. 1967, 27:87-106.
    • (1967) J. Mol. Biol. , vol.27 , pp. 87-106
    • LePecq, J.B.1    Paoletti, C.2
  • 17
    • 14844309624 scopus 로고    scopus 로고
    • PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery
    • Fukushima S., Miyata K., Nishiyama N., Kanayama N., Yamasaki Y., Kataoka K. PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery. J. Am. Chem. Soc. 2005, 127:2810-2811.
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 2810-2811
    • Fukushima, S.1    Miyata, K.2    Nishiyama, N.3    Kanayama, N.4    Yamasaki, Y.5    Kataoka, K.6
  • 18
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability retention effect for tumor targeting
    • Lyer A.K., Khaled G., Fang J., Maeda H. Exploiting the enhanced permeability retention effect for tumor targeting. Drug Discov. Today 2006, 11:812-818.
    • (2006) Drug Discov. Today , vol.11 , pp. 812-818
    • Lyer, A.K.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 19
    • 0037334516 scopus 로고    scopus 로고
    • Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications
    • Maeda H., Fang J., Inutsuka T., Kitamoto Y. Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications. Int. Immunopharmacol. 2003, 3:319-328.
    • (2003) Int. Immunopharmacol. , vol.3 , pp. 319-328
    • Maeda, H.1    Fang, J.2    Inutsuka, T.3    Kitamoto, Y.4
  • 20
    • 52049121804 scopus 로고    scopus 로고
    • An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
    • Chono S., Li S.D., Conwell C.C., Huang L. An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor. J. Control. Release 2008, 131:64-69.
    • (2008) J. Control. Release , vol.131 , pp. 64-69
    • Chono, S.1    Li, S.D.2    Conwell, C.C.3    Huang, L.4
  • 21
    • 21744451618 scopus 로고    scopus 로고
    • Folate-linked lipid-based nanoparticle for targeted gene delivery
    • Hattori Y., Maitani Y. Folate-linked lipid-based nanoparticle for targeted gene delivery. Curr. Drug Deliv. 2005, 2:243-252.
    • (2005) Curr. Drug Deliv. , vol.2 , pp. 243-252
    • Hattori, Y.1    Maitani, Y.2
  • 22
    • 41249102387 scopus 로고    scopus 로고
    • A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy
    • Duan Y., Zheng J., Han S., Wu Y., Wang Y., Li D., Kong D., Yu Y. A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy. J. Control. Release 2008, 127:173-179.
    • (2008) J. Control. Release , vol.127 , pp. 173-179
    • Duan, Y.1    Zheng, J.2    Han, S.3    Wu, Y.4    Wang, Y.5    Li, D.6    Kong, D.7    Yu, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.