Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain

Neural Development

Volumn 5, Issue 1, 2010, Pages

  Hammock, Elizabeth A D ^a,b   Eagleson, Kathie L ^c   Barlow, Susan ^a,d   Earls, Laurie R ^a,e   Miller, David M ^a,b   Levitt, Pat ^c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d Siskin Hosp for Phys Rehab   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; CAENORHABDITIS ELEGANS PROTEIN;

ANIMAL; ARTICLE; C57BL MOUSE; CAENORHABDITIS ELEGANS; CELL SEPARATION; CHROMOSOME MAP; FLOW CYTOMETRY; FOREBRAIN; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IN SITU HYBRIDIZATION; METABOLISM; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PHYSIOLOGY; SEQUENCE HOMOLOGY;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL SEPARATION; CHROMOSOME MAPPING; FLOW CYTOMETRY; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION PROFILING; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; NEUROGENESIS; NEURONS; PROSENCEPHALON; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 78649523475     PISSN: None     EISSN: 17498104     Source Type: Journal    
DOI: 10.1186/1749-8104-5-32     Document Type: Article

References (55)

1. Hebert JM, Fishell G. The genetics of early telencephalon patterning: some assembly required. Nat Rev Neurosci 2008, 9:678-685. 10.1038/nrn2463, 2669317, 19143049.
2. Levitt P. Disruption of interneuron development. Epilepsia 2005, 46(Suppl 7):22-28. 10.1111/j.1528-1167.2005.00305.x, 16201992.
3. Levitt P, Eagleson KL, Powell EM. Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders. Trends Neurosci 2004, 27:400-406. 10.1016/j.tins.2004.05.008, 15219739.
4. Eagleson KL, Hammock EAD, Levitt P. Interneuron pathophysiologies: paths to neurodevelopmental disorders. Developmental Plasticity of Inhibitory Circuitry 2010, 167-184. US: Springer, Pallas SL.
5. Markram H, Toledo-Rodriguez M, Wang Y, Gupta A, Silberberg G, Wu C. Interneurons of the neocortical inhibitory system. Nat Rev Neurosci 2004, 5:793-807. 10.1038/nrn1519, 15378039.
6. Butt SJ, Fuccillo M, Nery S, Noctor S, Kriegstein A, Corbin JG, Fishell G. The temporal and spatial origins of cortical interneurons predict their physiological subtype. Neuron 2005, 48:591-604. 10.1016/j.neuron.2005.09.034, 16301176.
7. Flames N, Marin O. Developmental mechanisms underlying the generation of cortical interneuron diversity. Neuron 2005, 46:377-381. 10.1016/j.neuron.2005.04.020, 15882635.
8. Wonders CP, Anderson SA. The origin and specification of cortical interneurons. Nat Rev Neurosci 2006, 7:687-696. 10.1038/nrn1954, 16883309.
9. Batista-Brito R, Machold R, Klein C, Fishell G. Gene expression in cortical interneuron precursors is prescient of their mature function. Cereb Cortex 2008, 18:2306-2317. 10.1093/cercor/bhm258, 2536702, 18250082.
10. Faux C, Rakic S, Andrews W, Yanagawa Y, Obata K, Parnavelas JG. Differential gene expression in migrating cortical interneurons during mouse forebrain development. J Comp Neurol 2010, 518:1232-1248.
11. Marsh ED, Minarcik J, Campbell K, Brooks-Kayal AR, Golden JA. FACS-array gene expression analysis during early development of mouse telencephalic interneurons. Dev Neurobiol 2008, 68:434-445. 10.1002/dneu.20602, 18172891.
12. Okaty BW, Miller MN, Sugino K, Hempel CM, Nelson SB. Transcriptional and electrophysiological maturation of neocortical fast-spiking GABAergic interneurons. J Neurosci 2009, 29:7040-7052. 10.1523/JNEUROSCI.0105-09.2009, 2749660, 19474331.
13. Willi-Monnerat S, Migliavacca E, Surdez D, Delorenzi M, Luthi-Carter R, Terskikh AV. Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision. Mol Cell Neurosci 2008, 37:845-856. 10.1016/j.mcn.2008.01.009, 18316204.
14. Fox RM, Von Stetina SE, Barlow SJ, Shaffer C, Olszewski KL, Moore JH, Dupuy D, Vidal M, Miller DM. A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics 2005, 6:42. 10.1186/1471-2164-6-42, 1079822, 15780142.
15. Von Stetina SE, Watson JD, Fox RM, Olszewski KL, Spencer WC, Roy PJ, Miller DM. Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system. Genome Biol 2007, 8:R135. 10.1186/gb-2007-8-7-r135, 2323220, 17612406.
16. Altschul SF, Wootton JC, Gertz EM, Agarwala R, Morgulis A, Schäffer AA, Yu YK. Protein database searches using compositionally adjusted substitution matrices. FEBS J 2005, 272:5101-5109. 10.1111/j.1742-4658.2005.04945.x, 1343503, 16218944.
17. WormBase. , http://www.wormbase.org/
18. Allen Brain Atlas. , http://www.brain-map.org/
19. GenePaint. , http://www.genepaint.org/
20. Jin Y, Jorgensen E, Hartwieg E, Horvitz HR. The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. J Neurosci 1999, 19:539-548.
21. Cinar H, Keles S, Jin Y. Expression profiling of GABAergic motor neurons in Caenorhabditis elegans. Curr Biol 2005, 15:340-346. 10.1016/j.cub.2005.02.025, 15723795.
22. Butt SJ, Sousa VH, Fuccillo MV, Hjerling-Leffler J, Miyoshi G, Kimura S, Fishell G. The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron 2008, 59:722-732. 10.1016/j.neuron.2008.07.031, 2562525, 18786356.
23. Friocourt G, Parnavelas JG. Mutations in ARX result in several defects involving GABAergic neurons. Front Cell Neurosci 2010, 4:4. 2841486, 20300201.
24. Cubelos B, Sebastián-Serrano A, Kim S, Redondo JM, Walsh C, Nieto M. Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons. Dev Neurobiol 2008, 68:917-925. 10.1002/dneu.20626, 2938960, 18327765.
25. Westmoreland JJ, McEwen J, Moore BA, Jin Y, Condie BG. Conserved function of Caenorhabditis elegans UNC-30 and mouse Pitx2 in controlling GABAergic neuron differentiation. J Neurosci 2001, 21:6810-6819.
26. Iulianella A, Sharma M, Vanden Heuvel GB, Trainor PA. Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Development 2009, 136:2329-2334. 10.1242/dev.032128, 2729345, 19542352.
27. Brain Gene Expression Map. , http://www.stjudebgem.org/web/mainPage/mainPage.php
28. Malfroy L, Roth MP, Carrington M, Borot N, Volz A, Ziegler A, Coppin H. Heterogeneity in rates of recombination in the 6-Mb region telomeric to the human major histocompatibility complex. Genomics 1997, 43:226-231. 10.1006/geno.1997.4800, 9244441.
29. Ahn J, Won TW, Kaplan DE, Londin ER, Kuzmic P, Gelernter J, Gruen JR. A detailed physical map of the 6p reading disability locus, including new markers and confirmation of recombination suppression. Hum Genet 2002, 111:339-349. 10.1007/s00439-002-0771-x, 12384775.
30. Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Böttcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, et al. Common variants conferring risk of schizophrenia. Nature 2009, 460:744-747.
31. Kato M, Das S, Petras K, Kitamura K, Morohashi K, Abuelo DN, Barr M, Bonneau D, Brady AF, Carpenter NJ, Cipero KL, Frisone F, Fukuda T, Guerrini R, Iida E, Itoh M, Lewanda AF, Nanba Y, Oka A, Proud VK, Saugier-Veber P, Schelley SL, Selicorni A, Shaner R, Silengo M, Stewart F, Sugiyama N, Toyama J, Toutain A, Vargas AL, et al. Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation. Hum Mutat 2004, 23:147-159. 10.1002/humu.10310, 14722918.
32. Amiel J, Laudier B, Attié-Bitach T, Trang H, de Pontual L, Gener B, Trochet D, Etchevers H, Ray P, Simonneau M, Vekemans M, Munnich A, Gaultier C, Lyonnet S. Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome. Nat Genet 2003, 33:459-461. 10.1038/ng1130, 12640453.
33. Pohlenz J, Dumitrescu A, Zundel D, Martiné U, Schönberger W, Koo E, Weiss RE, Cohen RN, Kimura S, Refetoff S. Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J Clin Invest 2002, 109:469-473. 150877, 11854318.
34. Sherr EH. The ARX story (epilepsy, mental retardation, autism, and cerebral malformations): one gene leads to many phenotypes. Curr Opin Pediatr 2003, 15:567-571. 10.1097/00008480-200312000-00004, 14631200.
35. Martin CL, Duvall JA, Ilkin Y, Simon JS, Arreaza MG, Wilkes K, Alvarez-Retuerto A, Whichello A, Powell CM, Rao K, Cook E, Geschwind DH. Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism. Am J Med Genet B Neuropsychiatr Genet 2007, 144B:869-876. 10.1002/ajmg.b.30530, 17503474.
36. Bhalla K, Phillips HA, Crawford J, McKenzie OL, Mulley JC, Eyre H, Gardner AE, Kremmidiotis G, Callen DF. The de novo chromosome 16 translocations of two patients with abnormal phenotypes (mental retardation and epilepsy) disrupt the A2BP1 gene. J Hum Genet 2004, 49:308-311. 10.1007/s10038-004-0145-4, 15148587.
37. Losh M, Sullivan PF, Trembath D, Piven J. Current developments in the genetics of autism: from phenome to genome. J Neuropathol Exp Neurol 2008, 67:829-837. 10.1097/NEN.0b013e318184482d, 2649757, 18716561.
38. Alarcon M, Cantor RM, Liu J, Gilliam TC, Geschwind DH. Autism Genetic Research Exchange Consortium. Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families. Am J Hum Genet 2002, 70:60-71. 10.1086/338241, 384904, 11741194.
39. Alarcon M, Yonan AL, Gilliam TC, Cantor RM, Geschwind DH. Quantitative genome scan and ordered-subsets analysis of autism endophenotypes support language QTLs. Mol Psychiatry 2005, 10:747-757. 10.1038/sj.mp.4001666, 15824743.
40. Liu J, Nyholt DR, Magnussen P, Parano E, Pavone P, Geschwind D, Lord C, Iversen P, Hoh J, Ott J, Gilliam TC. A genomewide screen for autism susceptibility loci. Am J Hum Genet 2001, 69:327-40. 10.1086/321980, 1235325, 11452361.
41. Okazaki S, Ohsawa M, Kuki I, Kawawaki H, Koriyama T, Ri S, Ichiba H, Hai E, Inoue T, Nakamura H, Goto Y, Tomiwa K, Yamano T, Kitamura K, Itoh M. Aristaless-related homeobox gene disruption leads to abnormal distribution of GABAergic interneurons in human neocortex: evidence based on a case of X-linked lissencephaly with abnormal genitalia (XLAG). Acta Neuropathol 2008, 116:453-462. 10.1007/s00401-008-0382-2, 18458920.
42. Gelman DM, Martini FJ, Nóbrega-Pereira S, Pierani A, Kessaris N, Marín O. The embryonic preoptic area is a novel source of cortical GABAergic interneurons. J Neurosci 2009, 29:9380-9389. 10.1523/JNEUROSCI.0604-09.2009, 19625528.
43. Wonders C, Anderson SA. Cortical interneurons and their origins. Neuroscientist 2005, 11:199-205. 10.1177/1073858404270968, 15911869.
44. Xu Q, Cobos I, De La Cruz E, Rubenstein JL, Anderson SA. Origins of cortical interneuron subtypes. J Neurosci 2004, 24:2612-2622. 10.1523/JNEUROSCI.5667-03.2004, 15028753.
45. Flandin P, Kimura S, Rubenstein JL. The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. J Neurosci 2010, 30:2812-2823. 10.1523/JNEUROSCI.4228-09.2010, 2865856, 20181579.
46. Miyoshi G, Hjerling-Leffler J, Karayannis T, Sousa VH, Butt SJ, Battiste J, Johnson JE, Machold RP, Fishell G. Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons. J Neurosci 2010, 30:1582-1594. 10.1523/JNEUROSCI.4515-09.2010, 2826846, 20130169.
47. Hobert O, Tessmar K, Ruvkun G. The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons. Development 1999, 126:1547-1562.
48. Martin DM, Skidmore JM, Fox SE, Gage PJ, Camper SA. Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Dev Biol 2002, 252:84-99. 10.1006/dbio.2002.0835, 12453462.
49. Jin Y, Hoskins R, Horvitz HR. Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein. Nature 1994, 372:780-783. 10.1038/372780a0, 7997265.
50. Melkman T, Sengupta P. Regulation of chemosensory and GABAergic motor neuron development by the C. elegans Aristaless/Arx homolog alr-1. Development 2005, 132:1935-1949. 10.1242/dev.01788, 15790968.
51. Cotter D, Kerwin R, al-Sarraji S, Brion JP, Chadwich A, Lovestone S, Anderton B, Everall I. Abnormalities of Wnt signalling in schizophrenia-evidence for neurodevelopmental abnormality. Neuroreport 1998, 9:1379-1383. 10.1097/00001756-199805110-00024, 9631433.
52. Toyota T, Yoshitsugu K, Ebihara M, Yamada K, Ohba H, Fukasawa M, Minabe Y, Nakamura K, Sekine Y, Takei N, Suzuki K, Itokawa M, Meerabux JM, Iwayama-Shigeno Y, Tomaru Y, Shimizu H, Hattori E, Mori N, Yoshikawa T. Association between schizophrenia with ocular misalignment and polyalanine length variation in PMX2B. Hum Mol Genet 2004, 13:551-561. 10.1093/hmg/ddh047, 14709596.
53. Philippi A, Tores F, Carayol J, Rousseau F, Letexier M, Roschmann E, Lindenbaum P, Benajjou A, Fontaine K, Vazart C, Gesnouin P, Brooks P, Hager J. Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis. BMC Med Genet 2007, 8:74. 10.1186/1471-2350-8-74, 2222245, 18053270.
54. Kato T. Molecular genetics of bipolar disorder and depression. Psychiatry Clin Neurosci 2007, 61:3-19. 10.1111/j.1440-1819.2007.01604.x, 17239033.
55. Gruters A, Biebermann H, Krude H. Neonatal thyroid disorders. Horm Res 2003, 59(Suppl 1):24-29.