The autoimmune TCR-Ob.2F3 can bind to MBP85-99/HLA-DR2 having an unconventional mode as in TCR-Ob.1A12

Molecular Immunology

Volumn 48, Issue 1-3, 2010, Pages 314-320

  Kato, Zenichiro ^a,b   Stern, Joel N H ^a   Nakamura, Hironori K ^b   Miyashita, Naoyuki ^b,c   Kuwata, Kazuo ^b   Kondo, Naomi ^b   Strominger, Jack L ^a  

^a HARVARD UNIVERSITY   (United States)

^b GIFU UNIVERSITY   (Japan)

^c RIKEN   (Japan)

Author keywords

Human leukocyte antigen (HLA); Multiple sclerosis; Myelin basic Protein; Structural docking; T cell receptor

Indexed keywords

HLA DR2 ANTIGEN; HYDROGEN; MYELIN BASIC PROTEIN; MYELIN BASIC PROTEIN[85-99]; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; AUTOIMMUNITY; COMPUTER SIMULATION; CONTROLLED STUDY; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SIMULATION; X RAY CRYSTALLOGRAPHY;

AUTOANTIGENS; CRYSTALLOGRAPHY, X-RAY; HLA-DR2 ANTIGEN; HUMANS; IMAGING, THREE-DIMENSIONAL; MODELS, STRUCTURAL; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ANTIGEN, T-CELL;

EID: 78649515939     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.07.010     Document Type: Article

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