Differences between cellular and molecular profiles of induced pluripotent stem cells generated from mouse embryonic fibroblasts

Cellular Reprogramming

Volumn 12, Issue 6, 2010, Pages 627-639

  Kim, Eun Young ^a   Jeon, Kilsoo ^b   Park, Hyo Young ^a   Han, Young Joon ^a   Yang, Byoung Chul ^c   Park, Soo Bong ^c   Chung, Hyung Min ^d   Park, Se Pill ^a  

^a Jeju National University   (South Korea)

^b Konkuk University   (South Korea)

^c National Institute of Animal Science   (South Korea)

^d CHA University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT PROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL DEATH; CELL DIFFERENTIATION; CELL STRUCTURE; CELL SUSPENSION; CONTROLLED STUDY; DNA MICROARRAY; EMBRYO; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; FEMALE; FIBROBLASTS; GENE EXPRESSION PROFILING; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; PREGNANCY;

IPS;

EID: 78649508014     PISSN: 21524971     EISSN: 21524998     Source Type: Journal    
DOI: 10.1089/cell.2010.0013     Document Type: Article

References (30)

1. Ashton, R.S., Peltier, J., Fasano, C.A., et al. (2007). High-throughput screening of gene function in stem cells using clonal microarrays. Stem Cells 25, 2928-2935.
2. Avilion, A.A., Nicolis, S.K., Pevny, L.H., et al. (2003). Multi-potent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 17, 126-140.
3. Chickarmane, V., and Peterson, C. (2008). A computational model for understanding stem cell, trophectoderm and en-doderm lineage determination. PLoS One 3, e3478.
4. Dalla-Favera, R., Bregni, M., Erikson, J., et al. (1982). Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl. Acad. Sci. USA 79, 7824-7827.
5. Feng, Q., Lu, S.J., Klimanskaya, I., et al. (2010). Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence. Stem Cells 12 [Epub ahead of print].
6. Foster, K.W., Frost, A.R., McKie-Bell, P., et al. (2000). Increase of GKLF messenger RNA and protein expression during progression of breast cancer. Cancer Res 60, 6488-6495.
7. Katz, J.P., Perreault, N., Goldstein, B.G., et al. (2002). The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129, 2619-2628.
8. Knoepfler, P.S., Zhang, X.Y., Cheng, P.F., et al. (2006). Myc influences global chromatin structure. EMBO J. 25, 2723-2734.
9. Livak, K.J., and Schmittgen, T.D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408.
10. Luo, Y., Schwartz, C., Shin, S., et al. (2006). A focused microarray to assess dopaminergic and glial cell differentiation from fetal tissue or embryonic stem cells. Stem Cells 24, 865-875.
11. Maherali, N., Sridharan, R., Xie, W., et al. (2007). Directly re-programmed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70.
12. Nakatake, Y., Fukui, N., Iwamatsu, Y., et al. (2006). Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells. Mol. Cell Biol. 26, 7772-7782.
13. Niwa, H., Miyazaki, J., and Smith, A.G. (2000). Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24, 372-376.
14. Niwa, H., Masui, S., Chambers, I., et al. (2002). Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells. Mol. Cell Biol. 22, 1526-1536.
15. Okamoto, K., Okazawa, H., Okuda, A., et al. (1990). A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60, 461-472.
16. Okita, K., Ichisaka, T., and Yamanaka, S. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317.
17. Okita, K., Nakagawa, M., Hyenjong, H., et al. (2008). Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949-953.
18. Park, I.H., Zhao, R., West, J.A., et al. (2008). Reprogramming of human somatic cells to pluripotency with defind factors. Nature 451, 141-146.
19. Sharova, L.V., Sharov, A.A., Piao, Y., et al. (2007). Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains. Dev. Biol. 307, 446-459.
20. Shimozaki K, Nakashima K, Niwa H, et al. (2003). Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis- inducing cultures. Development 130, 2505-2512.
21. Sridharan, R., Tchieu, J., Mason, M.J., et al. (2009). Role of the murine reprogramming factors in the induction of plur-ipoptency. Cell 136, 364-377.
22. Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
23. Takahashi, K., Tanabe, K., Ohnuki, M., et al. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defind factors. Cell 131, 861-872.
24. Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
25. Wernig, M., Meissner, A., Foreman, R., et al. (2007). In vitro reprogramming of fibroblasts into a pluripotent ES cell-like state. Nature 448, 318-324.
26. Yamanaka, S. (2007). Strategies and now developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1, 39-49.
27. Yu, J., Vodyanik, M.A., Smuga-Otto, K., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 19 Nov [Epub ahead of print] doi: 10.1126/ science.1151526.
28. Yuan, H., Corbi, N., Basilico, C., et al. (1995). Devel-opmentalspecific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 9, 2635-2645.
29. Zeineddine, D., Papadimou, E., Chebli, K., et al. (2006). Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development. Dev. Cell 11:535-546.
30. Zhou, H., Wu, S., Joo, J.Y., et al. (2009). Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384.