The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease

Biomaterials

Volumn 32, Issue 4, 2011, Pages 1157-1166

  Douglas, Temple A ^a   Tamburro, Davide ^a   Fredolini, Claudia ^a,b,c   Espina, Benjamin H ^d   Lepene, Benjamin S ^d   Ilag, Leopold ^e   Espina, Virginia ^a   Petricoin, Emanuel F ^a   Liotta, Lance A ^a   Luchini, Alessandra ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b S GIOVANNI BOSCO HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d CERES NANOSCIENCES INC   (United States)

^e STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Affinity; Bacteria; Hydrogel; Microparticle; Protein

Indexed keywords

ACRYLIC ACIDS; AFFINITY; AMIDATION; ANALYTES; BACTERIAL INFECTIONS; CARBOXYLIC GROUP; CLINICAL STUDY; DETECTION LIMITS; DETECTION SENSITIVITY; EARLY DIAGNOSIS; EXTRACTION YIELD; FUNCTIONALIZED; HIGH AFFINITY; HUMAN URINE; INFECTIOUS DISEASE; LOW CONCENTRATIONS; LYME DISEASE; MICRO PARTICLES; N-ISOPROPYLACRYLAMIDES; URINE TEST;

ACRYLIC MONOMERS; AMIDES; ANTIGENS; BACTERIA; BACTERIOLOGY; BIOMATERIALS; BODY FLUIDS; CARBOXYLIC ACIDS; DISEASES; EXTRACTION; HYDROGELS; ORGANIC ACIDS; PROTEINS;

DIAGNOSIS;

ACID BLACK 48; ACRYLIC ACID; BACTERIAL ANTIGEN; DYE; POLY(N ISOPROPYLACRYLAMIDE); UNCLASSIFIED DRUG;

AMIDATION; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DIAGNOSTIC ACCURACY; HUMAN; HYDROGEL; IMMUNOASSAY; IXODES; LYME DISEASE; PRIORITY JOURNAL; URINALYSIS; URINE LEVEL;

ANIMALS; ANTIGENS, BACTERIAL; BIOCOMPATIBLE MATERIALS; BIOLOGICAL MARKERS; BORRELIA BURGDORFERI; COLORING AGENTS; DIAGNOSTIC TESTS, ROUTINE; FEMALE; HUMANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; IXODES; LYME DISEASE; MALE; MATERIALS TESTING; MOLECULAR STRUCTURE; PARTICLE SIZE;

BACTERIA (MICROORGANISMS); IXODIDA;

EID: 78649448600     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.10.004     Document Type: Article

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