Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkers

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Longo, Caterina ^a,b   Patanarut, Alexis ^b   George, Tony ^b   Bishop, Barney ^b   Zhou, Weidong ^b   Fredolini, Claudia ^b   Ross, Mark M ^b   Espina, Virginia ^b   Pellacani, Giovanni ^a   Petricoin III, Emanuel F ^b   Liotta, Lance A ^b   Luchini, Alessandra ^b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b GEORGE MASON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC ACID; ALBUMIN; BIOLOGICAL MARKER; CYTOKINE; NANOSHELL; PLATELET DERIVED GROWTH FACTOR; POLY(N ISOPROPYLACRYLAMIDE); DIAGNOSTIC AGENT; NANOPARTICLE; PLASMA PROTEIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; BIOASSAY; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HYDROGEL; MASS SPECTROMETRY; NANOTECHNOLOGY; PRESERVATION; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; SYNTHESIS; BLOOD; CHEMISTRY; DIAGNOSIS, MEASUREMENT AND ANALYSIS; METABOLISM; METHODOLOGY;

BIOLOGICAL MARKERS; BLOOD PROTEINS; CYTOKINES; HYDROGEL; LABORATORY TECHNIQUES AND PROCEDURES; NANOPARTICLES; PLATELET-DERIVED GROWTH FACTOR; PROTEOMICS;

EID: 62849105848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004763     Document Type: Article

References (54)

1. Liotta LA, Ferrari M, Petricoin E (2003) Clinical proteomics: written in blood. Nature 425: 905.
2. Anderson NL, Anderson NG (2002) The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics 1: 845-867.
3. Petricoin EF, Ardekani AM, Hitt BA, Levine PJ, Fusaro VA, et al. (2002) Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359: 572-577.
4. Merrell K, Southwick K, Graves SW, Esplin MS, Lewis NE, et al. (2004) Analysis of low-abundance, low-molecular-weight serum proteins using mass spectrometry. J Biomol Tech 15: 238-248.
5. Petricoin EF, Belluco C, Araujo RP, Liotta LA (2006) The blood peptidome: a higher dimension of information content for cancer biomarker discovery. Nat Rev Cancer 6: 961-967.
6. Lopez MF, Mikulskis A, Kuzdzal S, Bennett DA, Kelly J, et al. (2005) High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures. Clin Chem 51: 1946-1954.
7. Zhou M, Lucas DA, Chan KC, Issaq HJ, Petricoin EF 3rd, et al. (2004) An investigation into the human serum "interactome". Electrophoresis 25: 1289-1298.
8. Ayache S, Panelli M, Marincola FM, Stroncek DF (2006) Effects of storage time and exogenous protease inhibitors on plasma protein levels. Am J Clin Pathol 126: 174-184.
9. Luchini A, Geho DH, Bishop B, Tran D, Xia C, et al. (2008) Smart hydrogel particles: biomarker harvesting: one-step affinity purification, size exclusion, and protection against degradation. Nano Lett 8: 350-361.
10. Hoffman AS (2002) Hydrogels for biomedical applications. Adv Drug Deliv Rev 54: 3-12.
11. Drury JL, Mooney DJ (2003) Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 24: 4337-4351.
12. Bowen-Pope DF, Malpass TW, Foster DM, Ross R (1984) Platelet-derived growth factor in vivo: levels, activity, and rate of clearance. Blood 64: 458-469.
13. Hennink WE, van Nostrum CF (2002) Novel crosslinking methods to design hydrogels. Adv Drug Deliv Rev 54: 13-36.
14. Pelton R (2000) Temperature-sensitive aqueous microgels. Adv Colloid Interface Sci 85: 1-33.
15. Nayak S, Gan D, Serpe MJ, Lyon LA (2005) Hollow thermoresponsive microgels. Small 1: 416-421.
16. Fortina P, Kricka LJ, Surrey S, Grodzinski P (2005) Nanobiotechnology: the promise and reality of new approaches to molecular recognition. Trends Biotechnol 23: 168-173.
17. Moghimi SM, Hunter AC, Murray JC (2005) Nanomedicine: current status and future prospects. FASEB J 19: 311-330.
18. Sakamoto JH, Smith BR, Xie B, Rokhlin SI, Lee SC, et al. (2005) The molecular analysis of breast cancer utilizing targeted nanoparticle based ultrasound contrast agents. Technol Cancer Res Treat 4: 627-636.
19. Li X, Ponten A, Aase K, Karlsson L, Abramsson A, et al. (2000) PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat Cell Biol 2: 302-309.
20. Fredriksson L, Li H, Eriksson U (2004) The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev 15: 197-204.
21. Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, et al. (2003) PDGFRA activating mutations in gastrointestinal stromal tumors. Science 299: 708-710.
22. Baxter EJ, Hochhaus A, Bolufer P, Reiter A, Fernandez JM, et al. (2002) The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA. Hum Mol Genet 11: 1391-1397.
23. Yu J, Ustach C, Kim HR (2003) Platelet-derived growth factor signaling and human cancer. J Biochem Mol Biol 36: 49-59.
24. Board R, Jayson GC (2005) Platelet-derived growth factor receptor (PDGFR): a target for anticancer therapeutics. Drug Resist Updat 8: 75-83.
25. Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, et al. (2003) Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21: 60-65.
26. McArthur GA, Demetri GD, van Oosterom A, Heinrich MC, Debiec-Rychter M, et al. (2005) Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib Target Exploration Consortium Study B2225. J Clin Oncol 23: 866-873.
27. Mathew P, Thall PF, Jones D, Perez C, Bucana C, et al. (2004) Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. J Clin Oncol 22: 3323-3329.
28. Kubo T, Piperdi S, Rosenblum J, Antonescu CR, Chen W, et al. (2008) Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma. Cancer 112: 2119-2129.
29. Kagami S, Kakinuma T, Saeki H, Tsunemi Y, Fujita H, et al. (2005) Increased serum CCL28 levels in patients with atopic dermatitis, psoriasis vulgaris and bullous pemphigoid. J Invest Dermatol 124: 1088-1090.
30. Jahnz-Rozyk K, Targowski T, Glodzinska-Wyszogrodzka E, Plusa T (2003) Cc-chemokine eotaxin as a marker of efficacy of specific immunotherapy in patients with intermittent IgE-mediated allergic rhinoconjunctivitis. Allergy 58: 595-601.
31. Robak E, Kulczycka L, Sysa-Jedrzejowska A, Wierzbowska A, Robak T (2007) Circulating proangiogenic molecules PIGF, SDF-1 and sVCAM-1 in patients with systemic lupus erythematosus. Eur Cytokine Netw 18: 181-187.
32. Baggiolini M, Dewald B, Moser B (1994) Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 55: 97-179.
33. Frederick MJ, Clayman GL (2001) Chemokines in cancer. Expert Rev Mol Med 3: 1-18.
34. Braude EA, Nachod FC (1955) Determination of Organic Structures by Physical Methods. New York: Academic Press.
35. Denizli A, Piskin E (2001) Dye-ligand affinity systems. J Biochem Biophys Methods 49: 391-416.
36. Sereikaite J, Bumelis VA (2006) Examination of dye-protein interaction by gel-permeation chromatography. Biomed Chromatogr 20: 195-199.
37. Fredolini C, Meani F, Reeder KA, Rucker S, Patanarut A, et al. (2008) Concentration and Preservation of Very Low Abundance Biomarkers in Urine, such as Human Growth Hormone (hGH), by Cibacron Blue F3G-A Loaded Hydrogel Particles. Nano Res 1: 502-518.
38. Uekama K, Hirayama F, Arima H (2006) Recent Aspect of Cyclodextrin-Based Drug Delivery System. J Inclusion Phenom Macrocyclic Chem 56: 3-8.
39. Jin S, Lee Y, Kang H. Methyl-b-cyclodextrin, a specific cholesterol-binding agent, inhibits melanogenesis in human melanocytes through activation of ERK. Arch Dermatol Res 8: 451-454.
40. Cai W, Yao X, Shao X, Pan Z (2005) Bimodal Complexations of Steroids with Cyclodextrins by a Flexible Docking Algorithm. J Inclusion Phenom Macrocyclic Chem 51: 41-51.
41. Borst C, Holzgrabe U (2008) Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography. J Chromatogr A.
42. Dodziuk H (2006) Cyclodextrins and Their Complexes: Chemistry, Analytical Methods, Applications. Hoboken: Wiley-VCH.
43. Elmas B, Onur M, Şenel S, Tuncel A (2002) Temperature controlled RNA isolation by N-isopropylacrylamide-vinylphenyl boronic acid copolymer latex. Colloid Polym Sci 280: 1137-1146.
44. Kataoka K, Miyazaki H, Okano T, Sakurai Y (1994) Sensitive Glucose-Induced Change of the Lower Critical Solution Temperature of Poly [N,N-(dimethylacrylamide)-co-3-(acrylamido)-phenylboronic acid] in Physiological Saline. Macromolecules 27: 1061-1062.
45. Lorand JP, Edwards JO (1959) Polyol Complexes and Structure of the Benzeneboronate Ion. J Org Chem 24: 769-774.
46. Mader HS, Wolfbeis OS (2008) Boronic acid based probes for microdetermination of saccharides and glycosylated biomolecules. Mikrochim Acta 162: 1-34.
47. Yamauchi A, Suzuki I, Hayashita T (2006) Saccharide recognition by Boronic Acid Fluorophore/Cyclodextrin Complexes in Water. In: Geddes CDL, Joseph R, eds. Glucose Sensing, Topics in Fluorescence Spectroscopy Springer. pp 237-258.
48. Zhang Y, Gao X, Hardcastle K, Wang B (2006) Water-soluble fluorescent boronic acid compounds for saccharide sensing: substituent effects on their fluorescence properties. Chemistry 12: 1377-1384.
49. Jones CD, Lyon LA (2000) Synthesis and Characterization of Multiresponsive Core-Shell Microgels. Macromolecules 33: 8301-8306.
50. Couvreur P, Reddy LH, Mangenot S, Poupaert JH, Desmaele D, et al. (2008) Discovery of new hexagonal supramolecular nanostructures formed by squalenoylation of an anticancer nucleoside analogue. Small 4: 247-253.
51. Cho EC, Kim JW, Fernandez-Nieves A, Weitz DA (2008) Highly responsive hydrogel scaffolds formed by three-dimensional organization of microgel nanoparticles. Nano Lett 8: 168-172.
52. Smith ER, Zurakowski D, Saad A, Scott RM, Moses MA (2008) Urinary biomarkers predict brain tumor presence and response to therapy. Clinical cancer research 14: 2378-2386.
53. Barratt J, Topham P (2007) Urine proteomics: the present and future of measuring urinary protein components in disease. CMAJ 177: 361-368.
54. Pecora R (1985) Dynamic Light Scattering: Applications of Photo Correlation Spectroscopy: Springer. 436 p.