Comparison of E1A CR3-dependent transcriptional activation across six different human adenovirus subgroups

Journal of Virology

Volumn 84, Issue 24, 2010, Pages 12771-12781

  Ablack, Jailal N G ^a   Pelka, Peter ^a   Yousef, Ahmed F ^a   Turnell, Andrew S ^b   Grand, Roger J A ^b   Mymryk, Joe S ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; C 4 ZINC FINGER DOMAIN WITHIN CONSERVED REGION 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A PROTEIN; ISOPROTEIN; MEDIATOR COMPONENT MEDIATOR COMPLEX SUBUNIT 23 PROTEIN; PROTEASOME COMPONENT HUMAN SUG 1; TATA BINDING PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS 5; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN VARIANT; RNA INTERFERENCE; TRANSACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS MUTANT; WILD TYPE;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ADENOVIRUS E1A PROTEINS; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELLS, CULTURED; EMBRYO, MAMMALIAN; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; LUCIFERASES; MEDIATOR COMPLEX; MICE; P300-CBP TRANSCRIPTION FACTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TATA-BOX BINDING PROTEIN; TRANSCRIPTIONAL ACTIVATION;

HUMAN ADENOVIRUS;

EID: 78649413522     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01243-10     Document Type: Article

References (34)

1. Avvakumov, N., A. E. Kajon, R. C. Hoeben, and J. S. Mymryk. 2004. Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses. Virology 329:477-492.
2. Avvakumov, N., J. Torchia, and J. S. Mymryk. 2003. Interaction of the HPV E7 proteins with the pCAF acetyltransferase. Oncogene 22:3833-3841.
3. Berk, A. J. 2005. Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 24:7673-7685. (Pubitemid 41670670)
4. Berk, A. J., F. Lee, T. Harrison, J. Williams, and P. A. Sharp. 1979. A pre-early adenovirus 5 gene product regulates synthesis of early messenger RNAs. Cell 17:935-944.
5. Bondesson, M., M. Mannervik, G. Akusjarvi, and C. Svensson. 1994. An adenovirus E1A transcriptional repressor domain functions as an activator when tethered to a promoter. Nucleic Acids Res. 22:3053-3060. (Pubitemid 24260635)
6. Boyer, T. G., M. E. Martin, E. Lees, R. P. Ricciardi, and A. J. Berk. 1999. Mammalian Srb/mediator complex is targeted by adenovirus E1A protein. Nature 399:276-279.
7. Bruton, R. K., P. Pelka, K. L. Mapp, G. J. Fonseca, J. Torchia, A. S. Turnell, J. S. Mymryk, and R. J. Grand. 2008. Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3. J. Virol. 82:8476-8486.
8. Chatton, B., J. L. Bocco, M. Gaire, C. Hauss, B. Reimund, J. Goetz, and C. Kedinger. 1993. Transcriptional activation by the adenovirus larger E1a product is mediated by members of the cellular transcription factor ATF family which can directly associate with E1a. Mol. Cell. Biol. 13:561-570.
9. Culp, J. S., L. C. Webster, D. J. Friedman, C. L. Smith, W.-J. Huang, F. Y.-H. Wu, M. Rosenberg, and R. P. Ricciardi. 1988. The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for transactivation. Proc. Natl. Acad. Sci. U. S. A. 85:6450-6454.
10. Fang, L., J. L. Stevens, A. J. Berk, and K. R. Spindler. 2004. Requirement of Sur2 for efficient replication of mouse adenovirus type 1. J. Virol. 78:12888-12900.
11. Frisch, S. M., and J. S. Mymryk. 2002. Adenovirus-5 e1a: paradox and paradigm. Nat. Rev. Mol. Cell Biol. 3:441-452.
12. Geisberg, J. V., W. S. Lee, A. J. Berk, and R. P. Ricciardi. 1994. The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein. Proc. Natl. Acad. Sci. U. S. A. 91:2488-2492.
13. Glenn, G. M., and R. P. Ricciardi. 1985. Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions. J. Virol. 56:66-74.
14. Grand, R. J., A. S. Turnell, G. G. Mason, W. Wang, A. E. Milner, J. S. Mymryk, S. M. Rookes, A. J. Rivett, and P. H. Gallimore. 1999. Adenovirus early region 1A protein binds to mammalian SUG1 - a regulatory component of the proteasome. Oncogene 18:449-458.
15. Guan, H., J. F. Williams, and R. P. Ricciardi. 2009. Induction of neuronal and tumor-related genes by adenovirus type 12 E1A. J. Virol. 83:651-661.
16. Harrison, T., F. Graham, and J. Williams. 1977. Host range mutants of adenovirus type 5 defective for growth in HeLa cells. Virology 77:319-329. (Pubitemid 8077549)
17. Jelsma, T. N., J. A. Howe, C. M. Evelegh, N. F. Cunniff, M. H. Skiadopoulos, M. R. Floroff, J. E. Denman, and S. T. Bayley. 1988. Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation. Virology 163:494-502.
18. Jones, N., and T. Shenk. 1979. An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc. Natl. Acad. Sci. U. S. A. 76:3665-3669.
19. Lee, W. S., C. C. Kao, G. O. Bryant, X. Liu, and A. J. Berk. 1991. Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor. Cell 67:365-376.
20. Liu, F., and M. R. Green. 1994. Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains. Nature 368:520-525.
21. Martin, K. J., J. W. Lillie, and M. R. Green. 1990. Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets. Nature 346:147-152.
22. Montell, C., E. F. Fisher, M. H. Caruthers, and A. J. Berk. 1982. Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature 295:380-384.
23. Moran, E., T. Grodzicker, R. J. Roberts, M. B. Mathews, and B. Zerler. 1986. Lytic and transforming functions of individual products of the adenovirus E1A gene. J. Virol. 57:765-775. (Pubitemid 16143955)
24. Moran, E., B. Zerler, T. M. Harrison, and M. B. Mathew. 1986. Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes. Mol. Cell. Biol. 6:3470-3480.
25. Pelka, P., J. N. Ablack, G. J. Fonseca, A. F. Yousef, and J. S. Mymryk. 2008. Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes. J. Virol. 82:7252-7263.
26. Pelka, P., J. N. Ablack, M. Shuen, A. F. Yousef, M. Rasti, R. J. Grand, A. S. Turnell, and J. S. Mymryk. 2009. Identification of a second independent binding site for the pCAF acetyltransferase in adenovirus E1A. Virology 391:90-98.
27. Pelka, P., J. N. Ablack, J. Torchia, A. S. Turnell, R. J. Grand, and J. S. Mymryk. 2009. Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP. Nucleic Acids Res. 37:1095-1106.
28. Rasti, M., R. J. Grand, A. F. Yousef, M. Shuen, J. S. Mymryk, P. H. Gallimore, and A. S. Turnell. 2006. Roles for APIS and the 20S proteasome in adenovirus E1A dependent transcription. EMBO J. 25:2710-2722.
29. Shuen, M., N. Avvakumov, J. Torchia, and J. S. Mymryk. 2003. The E1A proteins of all six human adenovirus subgroups target the p300/CBP acetyltransferases and the SAGA transcriptional regulatory complex. Virology 316:75-83.
30. Shuen, M., N. Avvakumov, P. G. Walfish, C. J. Brandl, and J. S. Mymryk. 2002. The adenovirus E1A protein targets the SAGA but not the ADA transcriptional regulatory complex through multiple independent domains. J. Biol. Chem. 277:30844-30851.
31. Stevens, J. L., G. T. Cantin, G. Wang, A. Shevchenko, A. Shevchenko, and A. J. Berk. 2002. Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit. Science 296:755-758.
32. Strom, A. C., P. Ohlsson, and G. Akusjarvi. 1998. AR1 is an integral part of the adenovirus type 2 E1A CR3 transactivation domain. J. Virol. 72:5978-5983.
33. Webster, L. C., and R. P. Ricciardi. 1991. trans-Dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor. Mol. Cell. Biol. 11:4287-4296.
34. Yousef, A. F., C. J. Brandl, and J. S. Mymryk. 2009. Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae. BMC Mol. Biol. 10:32.