A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): Does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?

BMC Geriatrics

Volumn 10, Issue , 2010, Pages

  Miller, Michelle D ^a   Yaxley, Alison ^a   Villani, Anthony ^a   Cobiac, Lynne ^a   Fraser, Robert ^a   Cleland, Leslie ^b   James, Michael ^b   Crotty, Maria ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FISH OIL; OMEGA 3 FATTY ACID;

AGED; ARTICLE; CACHEXIA; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET THERAPY; DOUBLE BLIND PROCEDURE; HIP FRACTURE; HUMAN; NUTRITIONAL STATUS; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; CACHEXIA; DOUBLE-BLIND METHOD; FATTY ACIDS, OMEGA-3; FISH OILS; HIP FRACTURES; HUMANS; NUTRITIONAL STATUS; TREATMENT OUTCOME;

EID: 78649402057     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/1471-2318-10-76     Document Type: Article

References (57)

1. Estimating Hip Fracture Morbidity, Mortality and Costs. RS Braithwaite NF Col JB Wong, Journal of the American Geriatrics Society 2003 51 364 370 10.1046/j.1532-5415.2003.51110.x 12588580
2. Mortality associated with delay in operation after hip fracture: observational study. A Bottle P Aylin, British Medical Journal 2006 332 947 951 10.1136/bmj.38790.468519.55 16554334
3. Mortality following hip fracture: Trends and geographical variations over the last 40 years. S Haleem L Lutchman R Mayahi JE Grice MJ Parker, Injury 2008 39 1157 1163 10.1016/j.injury.2008.03.022 18653186
4. Survival after hip fracture. B Farahmand K Michalsson A Ahlbom S Ljunghall J Baron, Osteoporosis International 2005 16 1583 1590 10.1007/s00198-005-2024-z 16217590
5. The human cost of fracture. J Pasco K Sanders F Hoekstra M Henry G Nicholson M Kotowicz, Osteoporosis International 2005 16 2046 2052 10.1007/s00198-005-1997-y 16228106
6. Evidence-based guidelines for the management of hip fractures in older persons: an update. J Mak I Cameron L March, Medical Journal of Australia 2010 192 37 41 20047547
7. Incidence of and Risk Factors for Falls Following Hip Fracture in Community-dwelling Older Adults. A Shumway-Cook MA Ciol W Gruber C Robinson, Physical Therapy 2005 85 648 655 15982171
8. Nutritional status of adults participating in ambulatory rehabilitation. S Kaur M Miller J Halbert L Giles M Crotty, Asia Pacific Journal of Clinical Nutrition 2008 17 199 207 18586637
9. Lower limb fracture, cognitive impairment and risk of subsequent malnutrition: a prospective evaluation of dietary energy and protein intake on an orthopaedic ward. MD Miller E Bannerman LA Daniels M Crotty, European Journal of Clinical Nutrition 2006 60 853 861 10.1038/sj.ejcn.1602390 16452913
10. The use of the Mini-Nutritional Assessment (MNA) tool in elderly orthopaedic patients. M Murphy C Brooks S New M Lumbers, European Journal of Clinical Nutrition 2000 54 555 562 10.1038/sj.ejcn.1601055 10918465
11. Nutritional supplementation of elderly hip fracture patients. A randomized, double-blind, placebo-controlled trial. J Espaulella H Guyer F Diaz-Escriu J Mellado-Navas M Castells M Pladevall, Age and Ageing 2000 29 425 431 10.1093/ageing/29.5.425 11108415
12. Undernourished patients with hip fracture: poor outcome is not due to excess infections. D Bruce I Laurence L Ng P Goldswain, Australasian Journal on Ageing 1999 18 119 123 10.1111/j.1741-6612.1999.tb00111.x
13. The Effects of Nutritional Status on Outcome After Hip Fracture. KJ Koval SG Maurer ET Su GB Aharonoff JD Zuckerman, Journal of Orthopaedic Trauma 1999 13 3 164 169 10.1097/00005131-199903000-00003 10206247
14. Nutritional supplementation for hip fracture aftercare in older people.[update of Cochrane Database Syst Rev. 2005;(2):CD001880; PMID: 15846625]. A Avenell HHG Handoll, Cochrane Database of Systematic Reviews 2006 D001880
15. Nutritional supplementation and resistance training in nutritionally at risk older adults following lower limb fracture: a randomized controlled trial. MD Miller M Crotty C Whitehead E Bannerman LA Daniels, Clinical Rehabilitation 2006 20 311 323 10.1191/0269215506cr942oa 16719029
16. A systematic review of protein and energy supplementation for hip fracture aftercare in older people. A Avenell H Handoll, European Journal of Clinical Nutrition 2003 57 895 903 10.1038/sj.ejcn.1601623 12879083
17. Cachexia: pathophysiology and clinical relevance. JE Morley DR Thomas M-MG Wilson, American Journal of Clinical Nutrition 2006 83 735 743 16600922
18. Undernutrition and risk of mortality in elderly patients within 1 year of hospital discharge. L Liu M Bopp P Roberson D Sullivan, Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2002 57 741 746
19. Rapid loss of appendicular skeletal muscle mass is associated with higher all-cause mortality in older men: the prospective MINOS study. P Szulc F Munoz F Marchand R Chapurlat PD Delmas, American Journal of Clinical Nutrition 2010 91 1227 1236 10.3945/ajcn.2009.28256 20237137
20. Muscle weakness and falls in older adults: a systematic review and meta-analysis. J Moreland J Richardson C Goldsmith C Clase, Journal of the American Geriatrics Society 2004 52 1121 1129 10.1111/j.1532-5415.2004.52310.x 15209650
21. Sensori-motor function, gait patterns and falls in community-dwelling women. S Lord D Lloyd L Keung, Age and Ageing 1996 25 292 299 10.1093/ageing/25.4.292 8831874
22. Cachexia and aging: an update based on the Fourth International Cachexia Meeting. J Morley S Anker W Evans, Journal of Nutrition, Health and Aging 2009 13 47 55 10.1007/s12603-009-0009-x
23. Calories and cachexia. J Morley, Current Opinion in Clinical Nutrition & Metabolic Care 2009 12 607 610
24. The metabolic response to stress: a case of complex nutrition support management. MM Cartwright, Critical Care Nursing Clinics of North America 2004 16 467 487 15571935
25. Association Between Interleukin-6 and Lower Extremity Function After Hip Fracture: The Role of Muscle Mass and Strength. RR Miller MD Shardell GE Hicks AR Cappola WG Hawkes JA Yu-Yahiro J Magaziner, Journal of the American Geriatrics Society 2008 56 1050 1056 10.1111/j.1532-5415.2008.01708.x 18410321
26. Cachexia. D Kotler, Annals of Internal Medicine 2000 133 622 634 11033592
27. Exercise training and plasma c-reactive protein and interleukin-6 in elderly people. B Nicklas F Hsu T Brinkley T Church B Goodpaster S Kritchevsky M Pahor, Journal of the American Geriatrics Society 2008 56 2045 2052 10.1111/j.1532-5415.2008.01994.x 19016938
28. Associations of elevated interleukin-6 and c-reactive protein levels with mortality in the elderly. T Harris L Ferrucci R Tracy M Corti S Wacholder W EttingerJr H Heimovitz H Cohen R Wallace, American Journal of Medicine 1999 106 506 512 10.1016/S0002-9343(99)00066-2 10335721
29. The association of plasma IL-6 levels with functional disability in community-dwelling elderly. H Cohen C Pieper T Harris K Rao M Currie, Journals of Gerontology: Series A: Biological Sciences and Medical Sciences 1997 52 201 208
30. Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons. D Taaffe T Harris L Ferrucci J Rowe T Seeman, Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2000 55 709 715
31. Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. L Cleland J French W Betts G Murphy M Elliott, Journal of Rheumatology 1988 15 1471 1475 2849682
32. Omega 3 fatty acids for prevention and treatment of cardiovascular disease. L Hooper R Thompson R Harrison C Summerbell H Moore H Worthington P Durrington A Ness N Capps G Davey Smith, Cochrane Database of Systematic Reviews 2004 4 D003177
33. Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia. A Dewey C Baughan T Dean B Higgins I Johnson, Cochrane Database of Systematic Reviews 2007 1 D004597
34. Current clinical applications of omega-6 and omega-3 fatty acids. S Lee K Gura S Kim D Arsenault B Bistrian M Puder, Nutrition in Clinical Practice 2006 21 323 341 10.1177/0115426506021004323 16870801
35. Validation of an FFQ for evaluation of EPA and DHA intake. M Lucas G Asselin C Mérette MJ Poulin S Dodin, Public Health Nutrition 2009 12 1783 1790 10.1017/S1368980008004333 19102810
36. Appetite assessment: simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents. MG Wilson DR Thomas LZ Rubenstein JT Chibnall S Anderson A Baxi MR Diebold JE Morley, American Journal of Clinical Nutrition 2005 82 1074 1081 16280441
37. Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. MF Folstein SE Folstein PR McHugh, Journal of Psychiatric Research 1975 12 189 198 10.1016/0022-3956(75)90026-6 1202204
38. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Y Guigoz B Vellas P Garry, Nutrition Reviews 1996 54 59 65 10.1111/j.1753-4887.1996.tb03793.x
39. The association between chronic illness and functional change among participants in a comprehensive geriatric assessment program. CY Cho CA Alessi M Cho HU Aronow AE Stuck LZ Rubenstein JC Beck, Journal of the American Geriatrics Society 1998 46 677 682 9625181
40. Independence in instrumental activities of daily living and its effect on mortality. GM Ginsberg R Hammerman-Rozenberg A Cohen J Stessman GM Ginsberg R Hammerman-Rozenberg A Cohen J Stessman, Aging-Clinical & Experimental Research 1999 11 161 168
41. Repeated chair stands as a measure of lower limb strength in sexagenarian women. EK McCarthy MA Horvat PA Holtsberg JM Wisenbaker, Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2004 59 1207 1212
42. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. JM Guralnik EM Simonsick L Ferrucci RJ Glynn LF Berkman DG Blazer PA Scherr RB Wallace, Journal of Gerontology 1994 49 85 94
43. Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and cc16 in human serum. G Kenis C Teunissen R De Jongh E Bosmans H Steinbusch M Maes, Cytokine 2002 19 228 235 10.1016/S1043-4666(02)91961-7 12393169
44. The Assessment of Quality of Life (AQoL) instrument: a psychometric measure of health-related quality of life. G Hawthorne J Richardson R Osborne, Quality of Life Research 1999 8 209 224 10.1023/A:1008815005736 10472152
45. Validity and reliability of the Edmonton Frail Scale. D Rolfson S Majumdar R Tsuyuki A Tahir K Rockwood, Age and Ageing 2006 35 526 529 10.1093/ageing/afl041 16757522
46. Effect of dietary supplementation with n-3 fatty acids on coronary artery bypass graft patency. J Eritsland H Arnesen K Grønseth NB Fjeld M Abdelnoor, American Journal of Cardiology 1996 77 31 36 10.1016/S0002-9149(97) 89130-8 8540453
47. Nutrient Reference Values for Australia and New Zealand Including Recommended Dietary Intakes. National Health and Medical Research Council, Canberra: Commonwealth of Australia 2006
48. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. GR Norman JA Sloan KW Wyrwich, Medical Care 2003 41 582 592 10.1097/00005650-200305000-00004 12719681
49. Principles of bone healing. IH Kalfas, Neurosurgical Focus 2001 10 1 4 10.3171/foc.2001.10.4.2
50. Food habits and appetite of elderly women at the time of a femoral neck fracture and after nutritional and anabolic support. P Carlsson J Tidermark S Ponzer A S'derqvist T Cederholm, Journal of Human Nutrition and Dietetics 2005 18 117 120 10.1111/j.1365-277X.2005.00594.x 15788020
51. Nutritional supplementation and resistance training in nutritionally at risk older adults following lower limb fracture: a randomized controlled trial. M Miller M Crotty C Whitehead E Bannerman L Daniels, Clinical Rehabilitation 2006 20 311 323 10.1191/0269215506cr942oa 16719029
52. Influence of macro-nutrient status on recovery after hip fracture. M Unosson A Christina P Bjurulf H Von Schenck J Larsson, Journal of Nutritional & Environmental Medicine 1995 5 23 34
53. Energy balance in elderly patients after surgery for a femoral neck fracture. D Jallut L Tappy M Kohut D Bloesch R Munger Y Schutz R Chiolero J Felber J Livio E Jequier, Journal of Parenteral and Enteral Nutrition 1990 14 563 568 10.1177/0148607190014006563 2273529
54. Resting energy expenditure measured longitudinally following hip fracture compared to predictive equations: is an injury adjustment required? M Miller L Daniels E Bannerman M Crotty, British Journal of Nutrition 2007 94 976 982 10.1079/BJN20051593
55. Protein and energy balance following femoral neck fracture in geriatric patients. K Nelson E Richards C Long K Martin J Geiger S Brooks R Gandy W Blakemore, Metabolism 1995 44 59 66 10.1016/0026-0495(95)90290-2 7854167
56. Nutritional assessment and intervention in patients admitted with a femoral neck fracture: a chronicle of missed opportunities. M Miller M Crotty C Whitehead L Daniels P Finucane, Australian Journal of Nutrition and Dietetics 2001 58 86 91
57. N-3 fatty acids, cancer and cachexia: a systematic review of the literature. R Colomer J Moreno-Nogueira P Garca-Luna P Garca-Peris A Garca-de-Lorenzo A Zarazaga L Quecedo J del Llano L Usn C Casimiro, British Journal of Nutrition 2007 97 823 831 10.1017/S000711450765795X 17408522