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Volumn 5, Issue 3, 2010, Pages 160-165

Monoclonal antibodies in solid tumours

Author keywords

Angiogenesis; Biomarker; Combination therapy; Epidermal growth factor receptor; Monoclonal antibodies; Solid tumors

Indexed keywords

ALPHA INTERFERON; ANTHRACYCLINE; BEVACIZUMAB; CATUMAXOMAB; CETUXIMAB; IRINOTECAN; MONOCLONAL ANTIBODY; PACLITAXEL; PANITUMUMAB; PERTUZUMAB; REMOVAB; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 78649356769     PISSN: 15748847     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488410791498833     Document Type: Article
Times cited : (4)

References (56)
  • 1
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256(5517): 495-7.
    • (1975) Nature , vol.256 , Issue.5517 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 3
    • 0023911111 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann L, Clark M, Waldmann H, Winter G. Reshaping human antibodies for therapy. Nature 1988; 332(6162): 323-7.
    • (1988) Nature , vol.332 , Issue.6162 , pp. 323-327
    • Riechmann, L.1    Clark, M.2    Waldmann, H.3    Winter, G.4
  • 4
    • 0027963484 scopus 로고
    • Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs
    • Green LL, Hardy MC, Maynard-Currie CE, et al. Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat Genet 1994; 7(1): 13-21.
    • (1994) Nat Genet , vol.7 , Issue.1 , pp. 13-21
    • Green, L.L.1    Hardy, M.C.2    Maynard-Currie, C.E.3
  • 5
    • 33644819090 scopus 로고    scopus 로고
    • Fully human therapeutic monoclonal antibodies
    • Weiner LM. Fully human therapeutic monoclonal antibodies. J Immunother 2006; 29(1): 1-9
    • (2006) J Immunother , vol.29 , Issue.1 , pp. 1-9
    • Weiner, L.M.1
  • 6
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235(4785): 177-82
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 7
    • 34447306848 scopus 로고    scopus 로고
    • Trastuzumab: Mechanism of action, resistance and future perspectives in HER2-over-expressing breast cancer
    • Valabrega G, Montemurro F, Aglietta M. Trastuzumab: mechanism of action, resistance and future perspectives in HER2-over-expressing breast cancer. Ann Oncol 2007; 18(6): 977-84
    • (2007) Ann Oncol , vol.18 , Issue.6 , pp. 977-984
    • Valabrega, G.1    Montemurro, F.2    Aglietta, M.3
  • 8
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344(11): 783-92
    • (2001) N Engl J Med , vol.344 , Issue.11 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 9
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab--mechanism of action and use in clinical practice
    • Hudis CA. Trastuzumab--mechanism of action and use in clinical practice. N Engl J Med 2007; 357(1): 39-51
    • (2007) N Engl J Med , vol.357 , Issue.1 , pp. 39-51
    • Hudis, C.A.1
  • 10
    • 1342311012 scopus 로고    scopus 로고
    • Clinical cardiac tolerability of trastuzumab
    • Perez EA, Rodeheffer R. Clinical cardiac tolerability of trastuzumab. J Clin Oncol 2004; 22(2): 322-9
    • (2004) J Clin Oncol , vol.22 , Issue.2 , pp. 322-329
    • Perez, E.A.1    Rodeheffer, R.2
  • 11
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002; 20(3): 719-26
    • (2002) J Clin Oncol , vol.20 , Issue.3 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3
  • 12
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999; 17(9): 2639-48
    • (1999) J Clin Oncol , vol.17 , Issue.9 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 13
    • 70350204423 scopus 로고    scopus 로고
    • Efficacy results from the ToGA trial: A phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC)
    • (Meeting Abstracts), LBA4509-
    • Van Cutsem E, Kang Y, Chung H, et al. Efficacy results from the ToGA trial: A phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC). J Clin Oncol (Meeting Abstracts) 2009; 27(18S): LBA4509-
    • (2009) J Clin Oncol , vol.27 , Issue.18 S
    • van Cutsem, E.1    Kang, Y.2    Chung, H.3
  • 14
    • 73849111072 scopus 로고    scopus 로고
    • Pertuzumab monotherapy following trastuzumab-based treatment: Activity and tolerability in patients with advanced HER2-positive breast cancer
    • Cortes J, Baselga J, Petrella T, et al. Pertuzumab monotherapy following trastuzumab-based treatment: Activity and tolerability in patients with advanced HER2-positive breast cancer. J Clin Oncol (Meeting Abstracts) 2009; 27(15S): 1022-
    • (2009) J Clin Oncol (Meeting Abstracts) , vol.27 , Issue.15 S , pp. 1022
    • Cortes, J.1    Baselga, J.2    Petrella, T.3    Al et, al.4
  • 15
    • 1942474587 scopus 로고    scopus 로고
    • The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
    • Nahta R, Hung MC, Esteva FJ. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res 2004; 64(7): 2343-6
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2343-2346
    • Nahta, R.1    Hung, M.C.2    Esteva, F.J.3
  • 16
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001; 2(2): 127-37
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.2 , pp. 127-137
    • Yarden, Y.1    Sliwkowski, M.X.2
  • 17
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • Herbst RS, Kim ES, Harari PM. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer. Expert Opin Biol Ther 2001; 1(4): 719-32
    • (2001) Expert Opin Biol Ther , vol.1 , Issue.4 , pp. 719-732
    • Herbst, R.S.1    Kim, E.S.2    Harari, P.M.3
  • 18
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354(6): 567-78
    • (2006) N Engl J Med , vol.354 , Issue.6 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 19
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351(4): 337-45
    • (2004) N Engl J Med , vol.351 , Issue.4 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 20
    • 59949091448 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
    • Bokemeyer C, Bondarenko I, Makhson A, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009; 27(5): 663-71
    • (2009) J Clin Oncol , vol.27 , Issue.5 , pp. 663-671
    • Bokemeyer, C.1    Bondarenko, I.2    Makhson, A.3
  • 21
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360(14): 1408-17
    • (2009) N Engl J Med , vol.360 , Issue.14 , pp. 1408-1417
    • van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 22
    • 71449100773 scopus 로고    scopus 로고
    • C. S, Schlichting M, Bokemeyer C. A meta-analysis of the CRYSTAL and OPUS studies combining cetuximab with chemotherapy (CT) as 1st-line treatment for patients (pts) with metastatic colorectal cancer (mCRC): Results according to KRAS and BRAF mutation status
    • Van Cutsem E, Rougier P, Köhne C, C. S, Schlichting M, Bokemeyer C. A meta-analysis of the CRYSTAL and OPUS studies combining cetuximab with chemotherapy (CT) as 1st-line treatment for patients (pts) with metastatic colorectal cancer (mCRC): Results according to KRAS and BRAF mutation status. Eur J Cancer Suppl 2009; 7(2): 345
    • (2009) Eur J Cancer Suppl , vol.7 , Issue.2 , pp. 345
    • van Cutsem, E.1    Rougier, P.2    Köhne, C.3
  • 23
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): An open-label randomised phase III trial
    • Pirker R, Pereira JR, Szczesna A, et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009; 373(9674): 1525-31
    • (2009) Lancet , vol.373 , Issue.9674 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 24
    • 0033559606 scopus 로고    scopus 로고
    • Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy
    • Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG, Jakobovits A. Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy. Cancer Res 1999; 59(6): 1236-43
    • (1999) Cancer Res , vol.59 , Issue.6 , pp. 1236-1243
    • Yang, X.D.1    Jia, X.C.2    Corvalan, J.R.3    Wang, P.4    Davis, C.G.5    Jakobovits, A.6
  • 25
    • 34548147248 scopus 로고    scopus 로고
    • Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer
    • Hecht JR, Patnaik A, Berlin J, et al. Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer. Cancer 2007; 110(5): 980-8
    • (2007) Cancer , vol.110 , Issue.5 , pp. 980-988
    • Hecht, J.R.1    Patnaik, A.2    Berlin, J.3
  • 26
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007; 25(13): 1658-64
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1658-1664
    • van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 27
    • 71249136106 scopus 로고    scopus 로고
    • Randomized phase 3 study of panitumumab with FOLFOX4 compared to FOLFOX4 alone as 1st-line treatment (tx) for metastatic colorectal cancer (mCRC): The PRIME trial
    • Douillard J, Siena S, Cassidy J, et al. Randomized phase 3 study of panitumumab with FOLFOX4 compared to FOLFOX4 alone as 1st-line treatment (tx) for metastatic colorectal cancer (mCRC): the PRIME trial. Eur J Cancer Suppl 2009; 7(3): 6
    • (2009) Eur J Cancer Suppl , vol.7 , Issue.3 , pp. 6
    • Douillard, J.1    Siena, S.2    Cassidy, J.3
  • 28
    • 63449142391 scopus 로고    scopus 로고
    • Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy
    • Peeters M, Siena S, Van Cutsem E, et al. Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy. Cancer 2009; 115(7): 1544-54
    • (2009) Cancer , vol.115 , Issue.7 , pp. 1544-1554
    • Peeters, M.1    Siena, S.2    van Cutsem, E.3
  • 29
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 2009; 27(12): 2091-6
    • (2009) J Clin Oncol , vol.27 , Issue.12 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3
  • 30
    • 36949037220 scopus 로고    scopus 로고
    • Phase I/II study of cetuximab dose-escalation in patients with metastatic colorectal cancer (mCRC) with no or slight skin reactions on cetuximab standard dose treatment (EVEREST): Pharmacokinetic (PK), Pharmacodynamic (PD) and efficacy data
    • Tejpar S, Peeters M, Humblet Y, et al. Phase I/II study of cetuximab dose-escalation in patients with metastatic colorectal cancer (mCRC) with no or slight skin reactions on cetuximab standard dose treatment (EVEREST): Pharmacokinetic (PK), Pharmacodynamic (PD) and efficacy data. J Clin Oncol (Meeting Abstracts) 2007; 25(18 suppl): 4037
    • (2007) J Clin Oncol (Meeting Abstracts) , vol.25 , Issue.SUPPL 18 , pp. 4037
    • Tejpar, S.1    Peeters, M.2    Humblet, Y.3
  • 31
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997; 57(20): 4593-9
    • (1997) Cancer Res , vol.57 , Issue.20 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3
  • 32
    • 78649370817 scopus 로고    scopus 로고
    • Avastin Prescribing Information. Genentech Inc. July 2009. Available from: URL:
    • Avastin Prescribing Information. Genentech Inc. July 2009. Available from: URL: http: //www.gene.com/gene/products/information/pdf/avastin-prescribing.pdf
  • 33
    • 70350002279 scopus 로고    scopus 로고
    • Adverse effects of anticancer agents that target the VEGF pathway
    • Chen HX, Cleck JN. Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol 2009; 6(8): 465-77
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.8 , pp. 465-477
  • 34
    • 59149100151 scopus 로고    scopus 로고
    • Intraperitoneal treatment of malignant ascites due to epithelial tumors with catumaxomab: A phase II/III study
    • Parsons S, Murawa PX, Koralewski P, et al. Intraperitoneal treatment of malignant ascites due to epithelial tumors with catumaxomab: A phase II/III study. J Clin Oncol (Meeting Abstracts) 2008; 26(15 suppl): 3000
    • (2008) J Clin Oncol (Meeting Abstracts) , vol.26 , Issue.SUPPL 15 , pp. 3000
    • Parsons, S.1    Murawa, P.X.2    Koralewski, P.3
  • 35
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6(2): 117-27
    • (2004) Cancer Cell , vol.6 , Issue.2 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3
  • 36
    • 51849111524 scopus 로고    scopus 로고
    • NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
    • Serra V, Markman B, Scaltriti M, et al. NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations. Cancer Res 2008; 68(19): 8022-30
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8022-8030
    • Serra, V.1    Markman, B.2    Scaltriti, M.3
  • 37
    • 0035915421 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
    • Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 2001; 93(24): 1852-7
    • (2001) J Natl Cancer Inst , vol.93 , Issue.24 , pp. 1852-1857
    • Lu, Y.1    Zi, X.2    Zhao, Y.3    Mascarenhas, D.4    Pollak, M.5
  • 38
    • 61749100826 scopus 로고    scopus 로고
    • Multicenter phase I clinical trial of daily and weekly RAD001 in combination with weekly paclitaxel and trastuzumab in patients with HER2-overexpressing metastatic breast cancer with prior resistance to trastuzumab
    • Andre F, Campone M, Hurvitz SA, et al. Multicenter phase I clinical trial of daily and weekly RAD001 in combination with weekly paclitaxel and trastuzumab in patients with HER2-overexpressing metastatic breast cancer with prior resistance to trastuzumab. J Clin Oncol (Meeting Abstracts) 2008; 26(15 suppl): 1003
    • (2008) J Clin Oncol (Meeting Abstracts) , vol.26 , Issue.15 suppl , pp. 1003
    • Andre, F.1    Campone, M.2    Hurvitz, S.A.3
  • 39
    • 65349101151 scopus 로고    scopus 로고
    • Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
    • Junttila TT, Akita RW, Parsons K, et al. Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941. Cancer Cell 2009; 15(5): 429-40
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 429-440
    • Junttila, T.T.1    Akita, R.W.2    Parsons, K.3
  • 40
    • 33746290773 scopus 로고    scopus 로고
    • Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation
    • Anido J, Scaltriti M, Bech Serra JJ, et al. Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation. EMBO J 2006; 25(13): 3234-44
    • (2006) EMBO J , vol.25 , Issue.13 , pp. 3234-3244
    • Anido, J.1    Scaltriti, M.2    Bech Serra, J.J.3
  • 41
    • 34247588567 scopus 로고    scopus 로고
    • Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
    • Scaltriti M, Rojo F, Ocana A, et al. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst 2007; 99(8): 628-38
    • (2007) J Natl Cancer Inst , vol.99 , Issue.8 , pp. 628-638
    • Scaltriti, M.1    Rojo, F.2    Ocana, A.3
  • 42
    • 2142641698 scopus 로고    scopus 로고
    • Rial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ, Sr., Needle MN, Kopit J, Mayer RJ. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004; 22(7): 1201-8
    • (2004) J Clin Oncol , vol.22 , Issue.7 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6    Phase, I.I.7
  • 43
    • 20144381957 scopus 로고    scopus 로고
    • Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
    • Chung KY, Shia J, Kemeny NE, et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 2005; 23(9): 1803-10
    • (2005) J Clin Oncol , vol.23 , Issue.9 , pp. 1803-1810
    • Chung, K.Y.1    Shia, J.2    Kemeny, N.E.3
  • 44
    • 33750615769 scopus 로고    scopus 로고
    • Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
    • Lenz HJ, Van Cutsem E, Khambata-Ford S, et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol 2006; 24(30): 4914-21
    • (2006) J Clin Oncol , vol.24 , Issue.30 , pp. 4914-4921
    • Lenz, H.J.1    van Cutsem, E.2    Khambata-Ford, S.3
  • 45
    • 17844362179 scopus 로고    scopus 로고
    • Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: A cohort study
    • Moroni M, Veronese S, Benvenuti S, et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. Lancet Oncol 2005; 6(5): 279-86
    • (2005) Lancet Oncol , vol.6 , Issue.5 , pp. 279-286
    • Moroni, M.1    Veronese, S.2    Benvenuti, S.3
  • 46
    • 34548258303 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab
    • Sartore-Bianchi A, Moroni M, Veronese S, et al. Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab. J Clin Oncol 2007; 25(22): 3238-45
    • (2007) J Clin Oncol , vol.25 , Issue.22 , pp. 3238-3245
    • Sartore-Bianchi, A.1    Moroni, M.2    Veronese, S.3
  • 47
    • 34548238762 scopus 로고    scopus 로고
    • Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
    • Khambata-Ford S, Garrett CR, Meropol NJ, et al. Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol 2007; 25(22): 3230-7
    • (2007) J Clin Oncol , vol.25 , Issue.22 , pp. 3230-3237
    • Khambata-Ford, S.1    Garrett, C.R.2    Meropol, N.J.3
  • 48
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008; 26(35): 5705-12
    • (2008) J Clin Oncol , vol.26 , Issue.35 , pp. 5705-5712
    • Di Nicolantonio, F.1    Martini, M.2    Molinari, F.3
  • 49
    • 67650380136 scopus 로고    scopus 로고
    • Biomarkers of response and resistance to antiangiogenic therapy
    • Jain RK, Duda DG, Willett CG, et al. Biomarkers of response and resistance to antiangiogenic therapy. Nat Rev Clin Oncol 2009; 6(6): 327-38
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.6 , pp. 327-338
    • Jain, R.K.1    Duda, D.G.2    Willett, C.G.3
  • 51
    • 59949102930 scopus 로고    scopus 로고
    • A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
    • Hecht JR, Mitchell E, Chidiac T, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009; 27(5): 672-80
    • (2009) J Clin Oncol , vol.27 , Issue.5 , pp. 672-680
    • Hecht, J.R.1    Mitchell, E.2    Chidiac, T.3
  • 52
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 2009; 360(6): 563-72
    • (2009) N Engl J Med , vol.360 , Issue.6 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3
  • 53
    • 31444451572 scopus 로고    scopus 로고
    • Trastuzumab-based treatment of HER2-positive breast cancer: An antibody-dependent cellular cytotoxicity mechanism?
    • Arnould L, Gelly M, Penault-Llorca F, et al. Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? Br J Cancer 2006; 94(2): 259-67
    • (2006) Br J Cancer , vol.94 , Issue.2 , pp. 259-267
    • Arnould, L.1    Gelly, M.2    Penault-Llorca, F.3
  • 54
    • 61449239114 scopus 로고    scopus 로고
    • Impact of Fc{gamma} RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan
    • Bibeau F, Lopez-Crapez E, Di Fiore F, et al. Impact of Fc{gamma} RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan. J Clin Oncol 2009; 27(7): 1122-9
    • (2009) J Clin Oncol , vol.27 , Issue.7 , pp. 1122-1129
    • Bibeau, F.1    Lopez-Crapez, E.2    Di Fiore, F.3
  • 55
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • Musolino A, Naldi N, Bortesi B, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 2008; 26(11): 1789-96
    • (2008) J Clin Oncol , vol.26 , Issue.11 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    Bortesi, B.3
  • 56
    • 56449129810 scopus 로고    scopus 로고
    • Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
    • Lewis Phillips GD, Li G, Dugger DL, et al. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res 2008; 68(22): 9280-90.
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9280-9290
    • Lewis Phillips, G.D.1    Li, G.2    Dugger, D.L.3


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