Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease

Science China Chemistry

Volumn 53, Issue 11, 2010, Pages 2337-2342

  Zhu, Wei ^a   Qiu, Xiaohui ^a   Xu, Xiaojie ^a,b   Lu, Chuanjian ^a  

^a GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

chronic kidney disease; complex network; molecular docking; traditional Chinese medicine (TCM)

Indexed keywords

ACTION MECHANISMS; CHINESE MEDICINAL PLANTS; CHINESE MEDICINES; CHRONIC KIDNEY DISEASE; CLASSIFICATION THEORY; COMPLEX NETWORK ANALYSIS; COMPLEX NETWORKS; COMPUTATIONAL APPROACH; COMPUTATIONAL NETWORKS; DRUG MOLECULES; INTERACTION NETWORKS; MOLECULAR DOCKING; MULTICOMPONENTS; PHARMACOLOGICAL RESEARCH; RESEARCH APPROACH; TARGET PROTEINS; TRADITIONAL CHINESE MEDICINE;

ACTIVE NETWORKS; DOCKING; ELECTRIC NETWORK ANALYSIS; MEDICINE; MOLECULAR MODELING; PROTEINS;

DRUG INTERACTIONS;

EID: 78649343670     PISSN: 16747291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11426-010-4082-0     Document Type: Article

References (31)

1. J. Coresh E. Selvin L.A. Stenvens J. Manzi J.W. Kusek P. Eggers F.V. Lente A.S. Levey 2007 Prevalence of chronic kidney disease in the United States JAMA 298 2038 2047 1:CAS:528:DC%2BD2sXht1yjsLnM 10.1001/jama.298.17.2038
2. Ye RG. Integration of Chinese and Western Medicine: Nephrology. Beijing: People's Health Press, 2004. 25
3. W. Zhu X.M. Wang L. Zhang X.Y. Li B.X. Wang 2005 Pharmacokinetic of rhein in healthy male volunteers following oral and retention enema administration of rhubarb extract: a single dose study Am J Chin Med 33 839 850 1:CAS:528:DC%2BD2MXht1GisLbO 10.1142/S0192415X05003508
4. J. Jia F. Zhu X.H. Ma Z.W. Cao Y.X. Li Y.Z. Chen 2009 Mechanisms of drug combinations: interaction and network perspectives Nat Rev Drug Discov 8 111 128 1:CAS:528:DC%2BD1MXhtFOqt7w%3D 10.1038/nrd2683
5. G.R. Zimmermann J. Lehár C.T. Keith 2007 Multi-target therapeutics: when the whole is greater than the sum of the parts Drug Discov Today 12 34 42 1:CAS:528:DC%2BD2sXhsFOjsg%3D%3D 10.1016/j.drudis.2006.11.008
6. C.J. Hippisley C. Coupland 2005 Effect of combinations of two drugs on all cause in patients with ischaemic heart disease: Nested case-control analysis Brit Med J 330 1059 1063 10.1136/bmj.330.7499.1059
7. C.H. Hennekens F.M. Sacks A. Tonkin J.W. Jukema R.P. Byington B. Pitt D.A. Berry S.M. Berry N.F. Ford A.J. Walker K. Natarajan S.L. Chen F.T. Fiedorek R. Belder 2003 Additive benefits of pravastain and aspirin to decrease risks of cardiovascular disease Arch Intern Med 164 40 44 10.1001/archinte.164.1.40
8. The Indian Polycap Study 2009 Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): A phase II, double-blind, randomised trial Lancet 373 1341 1351 10.1016/S0140-6736(09)60611-5
9. W. Zhu X.M. Ruan K.J. Chen 2006 A new insight into application of evidence-based medicine in TCM J Trad Chin Med 47 333 335
10. L. Wang G.B. Zhou P. Liu J.H. Song Y. Liang X.J. Yan F. Xu B.S. Wang J.H. Mao Z.X. Shen S.J. Chen Z. Chen 2008 Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia Proc Natl Acad Sci USA 105 4826 1:CAS:528: DC%2BD1cXkt12qt7k%3D 10.1073/pnas.0712365105
11. Editorial Committee of the Pharmacopoeia of People's Republic of China. The Pharmacopoeia of People's Republic of China (part 1). Beijing: Chemical Industry Press, 2005
12. Zhou JJ, Xie GR, Yan JX. Handbook of Chemical Composition in Chinese Herbal Original Plants. Beijing: Chemical Industry Press, 2004
13. Y. Assenov F. Ramírez S.E. Schelhorn M. Albrecht 2008 Computing topological parameters of biological networks Bioinformatics 24 282 284 1:CAS:528:DC%2BD1cXptlWntw%3D%3D 10.1093/bioinformatics/btm554
14. Xu XJ. Study on computer simulation for Chinese traditional compound medicine. Prog Chem, 11: 202-204
15. X.J. Xu 2006 New concepts and approaches for drug discovery based on traditional Chinese medicine Drug Discov Today 3 247 253
16. Q. Huang X.B. Qiao X.J. Xu 2007 Potential synergism and inhibitors to multiple target enzymes of Xuefu Zhuyu decoction in cardiac disease therapeutics: A computational approach Bioorg Med Chem Lett 17 1779 1783 1:CAS:528:DC%2BD2sXit1yrur4%3D 10.1016/j.bmcl.2006.12.078
17. X.D. Li Q. Huang X.J. Xu 2008 Target-ligand space distribution of the compound sets from XuefuZhuyu decoction, a traditional Chinese medicinal recipe Acta Phys-Chim Sin 24 547 551 1:CAS:528:DC%2BD1cXltlWqu7g%3D
18. D.H. Wu X.J. Xu 2009 Computational simulation of benefiting Qi and activating blood mechanism of traditional Chinese medicine Acta Phys-Chim Sin 25 446 450 1:CAS:528:DC%2BD1MXjslSmu7s%3D
19. J.Y. Gu G. Yuan Y.H. Zhu X.J. Xu 2009 Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan Sci China Ser B-Chem 52 1879 1884 10.1007/s11426-009-0265-y
20. D.J. Watts 2004 The "new" science of networks Annu Rev Sociol 30 243 270 10.1146/annurev.soc.30.020404.104342
21. H. Jeong B. Tombor R. Albert Z.N. Oltvai A.L. Barabasi 2000 The large-scale organization of metabolic networks Nature 407 651 654 1:CAS:528:DC%2BD3cXnsVOrsLs%3D 10.1038/35036627
22. O. Yoshie T. Imai H. Nomiyama 2001 Chemokines in immunity Adv Immunol 78 57 110 1:CAS:528:DC%2BD3MXlsV2kt7c%3D 10.1016/S0065-2776(01)78002-9
23. F. Rousset E. Garcia T. Defrance C. Peronne N. Vezzio D.H. Hsu R. Kastelein K.W. Moore J. Banchereau 1992 Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes Proc Natl Acad Sci USA 89 1890 1893 1:CAS:528:DyaK38Xhslajtr4%3D 10.1073/pnas.89.5.1890
24. J.T. Feng Q. Xu X.Y. Xue F.F. Zhang Y.S. Xiao X.M. Liang 2006 Preparation of standard multi-component of traditional Chinese medicine and construction for its library World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica 8 1 7
25. M. Campillos M. Kuhn A.C. Gavin L.J. Jensen P. Bork 2008 Drug target identification using side-effect similarity Science 321 263 266 1:CAS:528:DC%2BD1cXot1entbY%3D 10.1126/science.1158140
26. S. Günther M. Kuhn M. Dunkel M. Campillos C. Senger E. Petsalaki J. Ahmed E. Garcia Urdiales A. Gewiess L.J. Jensen R. Schneider R. Skoblo R.B. Russell P.E. Bourne P. Bork R. Preissner 2008 SuperTarget and Matador: resources for exploring drug-target relationships Nucl Acids Res 36 919 922 10.1093/nar/gkm862
27. M. Kuhn D. Szklarczyk A. Franceschini M. Campillos C.V. Mering L.J. Jensen A. Beyer P. Bork 2010 STITCH 2: An interaction network database for small molecules and proteins Nucl Acids Res 38 552 556 10.1093/nar/gkp937
28. C.T. Keith A.A. Borisy B.R. Stckwell 2005 Multicomponent therapentics for networked system Nat Rev Drug Discov 4 1 8 10.1038/nrd1609
29. P. Imming C. Sinning A. Meyer 2006 Drug, their targets and the nature and number of drug targets Nat Rev Drug Discov 5 821 834 1:CAS:528: DC%2BD28XhtVajsbbN 10.1038/nrd2132
30. H. Kitano 2007 A robustness-based approach to systems-oriented drug design Nat Rev Drug Discov 6 202 210 1:CAS:528:DC%2BD2sXit12rsbk%3D 10.1038/nrd2195
31. D.J. Watts S.H. Strogatz 1998 Collective dynamics of "small- world" networks Nature 393 440 442 1:CAS:528:DyaK1cXjs1Khsrk%3D 10.1038/30918