New concepts and approaches for drug discovery based on traditional Chinese medicine

Drug Discovery Today: Technologies

Volumn 3, Issue 3, 2006, Pages 247-253

  Xu, Xiaojie ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ENZYME INHIBITOR; EPHEDRINE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; FISETIN; FOLATE RECEPTOR; HARMALINE; HARMINE; IMMOBILIZED ENZYME; MATRINE; NEW DRUG; OXYMATRINE; PEGANUM NIGELLASTRUM EXTRACT; PHYLLANTUS URINARIA EXTRACT; PICEATANNOL; PLANT EXTRACT; POLYCLONAL ANTIBODY; POLYMER; POTASSIUM CHANNEL BLOCKING AGENT; PROTEINASE INHIBITOR; QUERCETIN; STEROID RECEPTOR; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; CHEMICAL STRUCTURE; CHINESE MEDICINE; COMPUTER AIDED DESIGN; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; MOLECULAR IMPRINTING; PEGANUM NIGELLASTRUM; PHARMACOPHORE; PHYLANTUS URINARIA; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SOLID PHASE EXTRACTION; TRADITIONAL MEDICINE;

EID: 33750935268     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2006.09.008     Document Type: Review

References (39)

1. Drasar P., et al. Recent advances in analysis of Chinese medical plant and traditional medicines. J. Chromatogr. B. 812 (2004) 3-21
2. Xu X.J., et al. Separation and screening of compounds of biological origin using molecularly imprinted polymers. J. Chromatogr. B. 804 (2004) 61-69
3. Balunas M.J., et al. Drug discovery from medicinal plants. Life Sci. 78 (2005) 431-441
4. Bradbury J. From Chinese medicine to anticancer drug. DDT. 10 (2005) 1131-1132
5. Stahl M., et al. Integrating molecular design resource within modern drug discovery research: the Roche experience. Drug Disov. Today 11 (2006) 326-333
6. Jorgensen W.L. The many roles of computation in drug discovery. Science 303 (2004) 1813-1818
7. Hou T.J., et al. recent development and application of virtual screening in drug discovery: an Overview. Curr. Pharma. Des. 10 (2004) 1011-1033
8. Qiao X.B., et al. A 3D structure database of compounds from chinese traditional medicine herbs. J. Chem. Inf. Comput. Sci. 42 (2002) 481-489
9. Shen J.S., et al. Virtual screening on natural products for discovery active compounds and target information. Curr. Med. Chem. 10 (2003) 2327-2342
10. Kim J.L., et al. Crystal structure of hepatitis C Virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell 87 (1996) 343-355
11. Duan D.L., et al. Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease. Bio. Med. Chem. Lett. 14 (2004) 6041-6044
12. Wang Y., et al. Search for more effective HCV NS3 protease inhibitors via modification of corilagin. Progress Nature Sci. 15 (2005) 896-901
13. Zuo G.Y., et al. In vitro anti HCV activities of Saxifraga melanocentra and its polyphenolic compounds. Antiviral Chem. Chemother. 16 (2005) 393-398
14. Bogustavasky J. HTS assay development: Is smaller really better?. Drug Discov. Dev. 7 (2004) 37-40
15. Deng G., et al. Application of mass spectrometry in early stages of target based drug discovery. J. Pharm. Biomed. Anal. 40 (2006) 528-538
16. Huang X.D., et al. Strategy for analysis and screening of bioactive compounds in traditional Chinese medicine. J. Chromatogr. B. 812 (2004) 71-84
17. Wang H.L., et al. Fractionation and analysis of Artemisia Capillaris Thumb by affinity chromatography with human serum albumin as stationary phase. J. Chromatogr. A. 870 (2000) 501-510
18. He J.L., et al. Coating and fusing cell membranes onto a silica surface and their chromatographic characteristics. Chromatography 54 (2001) 71-76
19. Jacek J. Frontal affinity chromatography with MS detection (FAC-MS) in drug discovery. Drug Discov. Today 10 (2005) 409-416
20. Schriemer D.C., et al. Biosensor alternative: frontal affinity chromatography. Anal. Chem. 76 (2004) 441A-448A
21. Schriemer D.C., et al. Micro-scale fronted affinity chromatography with mass spectro metric detector: a new method for the screening of compound libraries. Angew. Chem. Int. Ed. Engl. 37 (1998) 3383-3387
22. Zhu L.L., et al. Frontal affinity chromatography combined on-line with mass spectrometry: a tool for the binding study of different epidermal growth factor receptor inhibitor. Anal. Chem. 75 (2003) 6388-6393
23. Luo H.P., et al. Frontal Immunoaffinity Chromatography with mass spectrometric detection: a method for finding active compounds from traditional Chinese herbs. Anal. Chem. 75 (2003) 3994-3998
24. Zhang B., et al. Frontal affinity chromatography coupled to mass spectrometry for screening mixtures of enzyme inhibitors. Anal. BioChem. 299 (2001) 173-182
25. Hodgsom R.J., et al. Inhibitor screening using immobilized enzyme reactor chromatography/mass spectrometry. Anal. Chem. 75 (2005) 7512-7519
26. Yi L. Small molecules blocking the entry of severe acute respioatory syndrome coronavirus into host cells. J. Virology 78 (2004) 11334-11339
27. Kandimalla V.B., et al. Molecular imprinting: a dynamic technique for diverse applications in analytical chemistry. Anal. Bio. Chem. 380 (2004) 587-605
28. Ye L., et al. Molecularly imprinted polymers as antibody and receptor mimics for assays, sensors and drug discovery. Anal. Bio. Chem. 378 (2004) 1887-1897
29. Rathbone D.L. Molecularly imprinted polymers in the drug discovery process. Adv. Drug Deliv. Rev. 57 (2005) 1854-1874
30. Dong X.C., et al. Molecularly imprinted solid-phase extraction of (-)-ephedrine from Chinese Ephedra. J. Chromatogr. A. 1070 (2005) 125-130
31. Li L., et al. Solid-phase extraction of active component of Chinese traditional medicine fisetin by using molecularly imprinted polymers. Chem. J. Chin. Univ. -Chin. 27 (2006) 608-611
32. Zhu L.L., et al. Application of a molecularly imprinted polymer for the effective recognition of different anti-epidernal growth factor receptor inhibitors. Anal. Chem. 75 (2003) 6381-6387
33. Zhu L.L., et al. Selective separation of active inhibitors of epidermal growth factor receptor from Caragana Jubata by molecularly imprinted solid-phase. J. Chromatogr. A 991 (2003) 151-158
34. Xie J., et al. Affinitive separation and on-line identification of antitumor compounds from Peganum nigellastrum by coupling a chromatographic column of target analogue imprinted polymer with mass spectrometry. Anal. Chem. 74 (2002) 2352-2360
35. Caro E., et al. Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples. Trends Anal. Chem. 25 (2006) 143-154
36. Xie J., et al. Selective extraction of functional compounds derived from herb in plasma by using a molecularly imprinted polymer based of 2,2-bis(hydroxymethyl)butanol trimethacrylate. J. Chromatogr. B 788 (2003) 233-242
37. Vuorela P., et al. Nature Products in the Process of Finding New Drug Candidates. Curr. Med. Chem. 11 (2004) 2375-2389
38. Chen Y.Z., et al. Introduction of Chinese Methods in Study of Modernization of Traditional Chinese Medicines (2003), Science publishing
39. Wang J.M. Hierarchical database screening for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking and MM-PB/SA. J. Med. Chem. 48 (2005) 2432-2444