메뉴 건너뛰기




Volumn 42, Issue 12, 2010, Pages 860-867

Hepatic VLDL-TG production and MTP gene expression are decreased in ovariectomized rats: Effects of exercise training

Author keywords

diacylglycerol acyltransferase 1 and 2; hepatic steatosis; lipid infusion; microsomal triglyceride transfer protein

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE 2; ESTRADIOL; ESTROGEN; INTRALIPID; LIPOPROTEIN LIPASE; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; TRIACYLGLYCEROL; TYLOXAPOL; VERY LOW DENSITY LIPOPROTEIN;

EID: 78649334497     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0030-1267173     Document Type: Article
Times cited : (27)

References (40)
  • 2
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002 287 356-359
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 3
    • 33748179703 scopus 로고    scopus 로고
    • Weight loss as a treatment for nonalcoholic fatty liver disease
    • Clark JM. Weight loss as a treatment for nonalcoholic fatty liver disease. J Clin Gastroenterol 2006 40 S39-S43
    • (2006) J Clin Gastroenterol , vol.40
    • Clark, J.M.1
  • 5
    • 27744513348 scopus 로고    scopus 로고
    • Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways
    • DEon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem 2005 280 35983-35991
    • (2005) J Biol Chem , vol.280 , pp. 35983-35991
    • Deon, T.M.1    Souza, S.C.2    Aronovitz, M.3    Obin, M.S.4    Fried, S.K.5    Greenberg, A.S.6
  • 7
    • 63349089791 scopus 로고    scopus 로고
    • Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver
    • Paquette A, Wang D, Jankowski M, Gutkowska J, Lavoie JM. Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver. Menopause 2008 15 1169-1175
    • (2008) Menopause , vol.15 , pp. 1169-1175
    • Paquette, A.1    Wang, D.2    Jankowski, M.3    Gutkowska, J.4    Lavoie, J.M.5
  • 8
    • 70149110292 scopus 로고    scopus 로고
    • Fatty acid oxidation is decreased in the liver of ovariectomized rats
    • Paquette A, Chapados NA, Bergeron R, Lavoie JM. Fatty acid oxidation is decreased in the liver of ovariectomized rats. Horm Metab Res 2009 41 511-515
    • (2009) Horm Metab Res , vol.41 , pp. 511-515
    • Paquette, A.1    Chapados, N.A.2    Bergeron, R.3    Lavoie, J.M.4
  • 9
    • 0026072558 scopus 로고
    • Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins
    • Walsh BW, Schiff I, Rosner B, Greenberg L, Ravnikar V, Sacks FM. Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 1991 325 1196-1204
    • (1991) N Engl J Med , vol.325 , pp. 1196-1204
    • Walsh, B.W.1    Schiff, I.2    Rosner, B.3    Greenberg, L.4    Ravnikar, V.5    Sacks, F.M.6
  • 10
    • 0029103223 scopus 로고
    • Ovariectomy decreases plasma triglyceride levels in analbuminaemic rats by lowering hepatic triglyceride secretion
    • Joles JA, Bijleveld C, van Tol A, Geelen MJ, Koomans HA. Ovariectomy decreases plasma triglyceride levels in analbuminaemic rats by lowering hepatic triglyceride secretion. Atherosclerosis 1995 117 51-59
    • (1995) Atherosclerosis , vol.117 , pp. 51-59
    • Joles, J.A.1    Bijleveld, C.2    Van Tol, A.3    Geelen, M.J.4    Koomans, H.A.5
  • 13
    • 0042922562 scopus 로고    scopus 로고
    • Sex difference in hepatic microsomal triglyceride transfer protein expression is determined by the growth hormone secretory pattern in the rat
    • Ameen C, Oscarsson J. Sex difference in hepatic microsomal triglyceride transfer protein expression is determined by the growth hormone secretory pattern in the rat. Endocrinology 2003 144 3914-3921
    • (2003) Endocrinology , vol.144 , pp. 3914-3921
    • Ameen, C.1    Oscarsson, J.2
  • 14
  • 15
    • 20444405347 scopus 로고    scopus 로고
    • Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1
    • Yamazaki T, Sasaki E, Kakinuma C, Yano T, Miura S, Ezaki O. Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1. J Biol Chem 2005 280 21506-21514
    • (2005) J Biol Chem , vol.280 , pp. 21506-21514
    • Yamazaki, T.1    Sasaki, E.2    Kakinuma, C.3    Yano, T.4    Miura, S.5    Ezaki, O.6
  • 17
    • 33745298222 scopus 로고    scopus 로고
    • Regulation of fat metabolism in the liver: Link to non-alcoholic hepatic steatosis and impact of physical exercise
    • Lavoie JM, Gauthier MS. Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise. Cell Mol Life Sci 2006 63 1393-1409
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1393-1409
    • Lavoie, J.M.1    Gauthier, M.S.2
  • 18
    • 0018220382 scopus 로고
    • Reduced triglyceride secretion: A metabolic consequence of chronic exercise
    • Simonelli C, Eaton RP. Reduced triglyceride secretion: a metabolic consequence of chronic exercise. Am J Physiol 1978 234 E221-E227
    • (1978) Am J Physiol , vol.234
    • Simonelli, C.1    Eaton, R.P.2
  • 20
    • 65649122273 scopus 로고    scopus 로고
    • Effects of exercise training on hepatic microsomal triglyceride transfer protein content in rats
    • Chapados NA, Seelaender M, Levy E, Lavoie JM. Effects of exercise training on hepatic microsomal triglyceride transfer protein content in rats. Horm Metab Res 2009 41 287-293
    • (2009) Horm Metab Res , vol.41 , pp. 287-293
    • Chapados, N.A.1    Seelaender, M.2    Levy, E.3    Lavoie, J.M.4
  • 22
    • 0021289192 scopus 로고
    • Ovariectomy leads to a rapid increase in rat placental lactogen secretion
    • Robertson MC, Owens RE, Klindt J, Friesen HG. Ovariectomy leads to a rapid increase in rat placental lactogen secretion. Endocrinology 1984 114 1805-1811
    • (1984) Endocrinology , vol.114 , pp. 1805-1811
    • Robertson, M.C.1    Owens, R.E.2    Klindt, J.3    Friesen, H.G.4
  • 23
    • 2042426317 scopus 로고    scopus 로고
    • Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability
    • El-Mas MM, Abdel-Rahman AA. Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability. J Cardiovasc Pharmacol 2004 43 607-615
    • (2004) J Cardiovasc Pharmacol , vol.43 , pp. 607-615
    • El-Mas, M.M.1    Abdel-Rahman, A.A.2
  • 24
    • 2442477510 scopus 로고    scopus 로고
    • Regulation of hepatic apolipoprotein B-lipoprotein assembly and secretion by the availability of fatty acids. I. Differential response to the delivery of fatty acids via albumin or remnant-like emulsion particles
    • Zhang YL, Hernandez-Ono A, Ko C, Yasunaga K, Huang LS, Ginsberg HN. Regulation of hepatic apolipoprotein B-lipoprotein assembly and secretion by the availability of fatty acids. I. Differential response to the delivery of fatty acids via albumin or remnant-like emulsion particles. J Biol Chem 2004 279 19362-19374
    • (2004) J Biol Chem , vol.279 , pp. 19362-19374
    • Zhang, Y.L.1    Hernandez-Ono, A.2    Ko, C.3    Yasunaga, K.4    Huang, L.S.5    Ginsberg, H.N.6
  • 25
    • 0033209998 scopus 로고    scopus 로고
    • Lipid metabolism
    • Lewis GF. Lipid metabolism. Curr Opin Lipidol 1999 10 457-475
    • (1999) Curr Opin Lipidol , vol.10 , pp. 457-475
    • Lewis, G.F.1
  • 27
    • 0027531667 scopus 로고
    • Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: Information obtained from cultured liver cells
    • Dixon JL, Ginsberg HN. Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: information obtained from cultured liver cells. J Lipid Res 1993 34 167-179
    • (1993) J Lipid Res , vol.34 , pp. 167-179
    • Dixon, J.L.1    Ginsberg, H.N.2
  • 29
    • 24744442832 scopus 로고    scopus 로고
    • Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors
    • Lemieux C, Gelinas Y, Lalonde J, Labrie F, Cianflone K, Deshaies Y. Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors. J Lipid Res 2005 46 1285-1294
    • (2005) J Lipid Res , vol.46 , pp. 1285-1294
    • Lemieux, C.1    Gelinas, Y.2    Lalonde, J.3    Labrie, F.4    Cianflone, K.5    Deshaies, Y.6
  • 30
    • 39849093869 scopus 로고    scopus 로고
    • Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice
    • Liu Y, Millar JS, Cromley DA, Graham M, Crooke R, Billheimer JT, Rader DJ. Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice. Biochim Biophys Acta 2008 1781 97-104
    • (2008) Biochim Biophys Acta , vol.1781 , pp. 97-104
    • Liu, Y.1    Millar, J.S.2    Cromley, D.A.3    Graham, M.4    Crooke, R.5    Billheimer, J.T.6    Rader, D.J.7
  • 31
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Bjornstrom L, Sjoberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 2005 19 833-842
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Bjornstrom, L.1    Sjoberg, M.2
  • 33
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells
    • Razandi M, Pedram A, Greene GL, Levin ER. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol Endocrinol 1999 13 307-319
    • (1999) Mol Endocrinol , vol.13 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 34
    • 0028925081 scopus 로고
    • Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding
    • Pappas TC, Gametchu B, Watson CS. Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding. FASEB J 1995 9 404-410
    • (1995) FASEB J , vol.9 , pp. 404-410
    • Pappas, T.C.1    Gametchu, B.2    Watson, C.S.3
  • 35
    • 0037224484 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones
    • Losel R, Wehling M. Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 2003 4 46-56
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 46-56
    • Losel, R.1    Wehling, M.2
  • 36
    • 77951866235 scopus 로고    scopus 로고
    • Does exercise training prior to ovariectomy protect against liver and adipocyte fat accumulation in rats?
    • Pighon A, Barsalani R, Yasari S, Prudhomme D, Lavoie JM. Does exercise training prior to ovariectomy protect against liver and adipocyte fat accumulation in rats? Climacteric 2010 13 238-248
    • (2010) Climacteric , vol.13 , pp. 238-248
    • Pighon, A.1    Barsalani, R.2    Yasari, S.3    Prudhomme, D.4    Lavoie, J.M.5
  • 37
    • 0025358698 scopus 로고
    • Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes
    • Sparks JD, Sparks CE. Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes. J Biol Chem 1990 265 8854-8862
    • (1990) J Biol Chem , vol.265 , pp. 8854-8862
    • Sparks, J.D.1    Sparks, C.E.2
  • 38
    • 54049094000 scopus 로고    scopus 로고
    • FoxO1 integrates insulin signaling to VLDL production
    • Kamagate A, Dong HH. FoxO1 integrates insulin signaling to VLDL production. Cell Cycle 2008 7 3162-3170
    • (2008) Cell Cycle , vol.7 , pp. 3162-3170
    • Kamagate, A.1    Dong, H.H.2
  • 39
    • 0027945062 scopus 로고
    • Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators
    • Hagan DL, Kienzle B, Jamil H, Hariharan N. Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators. J Biol Chem 1994 269 28737-28744
    • (1994) J Biol Chem , vol.269 , pp. 28737-28744
    • Hagan, D.L.1    Kienzle, B.2    Jamil, H.3    Hariharan, N.4
  • 40
    • 4644235275 scopus 로고    scopus 로고
    • Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance
    • Hawley JA. Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance. Diabetes Metab Res Rev 2004 20 383-393
    • (2004) Diabetes Metab Res Rev , vol.20 , pp. 383-393
    • Hawley, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.