Association between cyclin D1 polymorphism with CpG island promoter methylation status of tumor suppressor genes in gastric cancer

Digestive Diseases and Sciences

Volumn 55, Issue 12, 2010, Pages 3449-3457

  Tahara, Tomomitsu ^a   Shibata, Tomoyuki ^a   Nakamura, Masakatsu ^a   Yamashita, Hiromi ^a   Yoshioka, Daisuke ^a   Okubo, Masaaki ^a   Yonemura, Joh ^a   Maeda, Yoshiteru ^a   Maruyama, Naoko ^a   Kamano, Toshiaki ^a   Kamiya, Yoshio ^a   Fujita, Hiroshi ^a   Nakagawa, Yoshihito ^a   Nagasaka, Mitsuo ^a   Iwata, Masami ^a   Hirata, Ichiro ^a   Arisawa, Tomiyasu ^b  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

CCND1; CpG island hypermethylation; G870A; Gastric cancer; Methylation specific polymerase chain reaction; Polymorphism

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DEATH ASSOCIATED PROTEIN KINASE; UVOMORULIN;

ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CPG ISLAND; DNA METHYLATION; DNA POLYMORPHISM; EPIGENETICS; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HELICOBACTER INFECTION; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; STOMACH CANCER; TUMOR SUPPRESSOR GENE;

AGED; CPG ISLANDS; DNA METHYLATION; FEMALE; GENES, BCL-1; GENES, TUMOR SUPPRESSOR; GENOTYPE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS;

EID: 78649316677     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1206-5     Document Type: Article

References (48)

1. H Rizos AP Darmanian GJ Mann RF Kefford 2000 Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization Oncogene 19 2978 2985 1:CAS:528:DC%2BD3cXksF2ns7Y%3D 10.1038/sj.onc.1203629 10871849
2. A Tannapfel C Busse L Weinans M Benicke A Katalinic F Geissler J Hauss C Wittekind 2001 INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas Oncogene 20 7104 7109 1:CAS:528:DC%2BD3MXotlCgu78%3D 10.1038/sj.onc.1204902 11704835
3. M Toyota N Ahuja H Suzuki F Itoh M Ohe-Toyota K Imai SB Baylin JP Issa 1999 Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype Cancer Res 59 5438 5442 1:CAS:528:DyaK1MXnt1Gjurw%3D 10554013
4. GH Kang YH Shim HY Jung WH Kim JY Ro MG Rhyu 2001 CpG island methylation in premalignant stages of gastric carcinoma Cancer Res 61 2847 2851 1:CAS:528:DC%2BD3MXivFGru74%3D 11306456
5. AO Chan SK Lam BC Wong WM Wong MF Yuen YH Yeung WM Hui A Rashid YL Kwong 2003 Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer Gut 52 502 506 1:CAS:528:DC%2BD3sXjtVKltLg%3D 10.1136/gut.52.4.502 12631658
6. T Raveh A Kimchi 2001 DAP kinase-a proapoptotic gene that functions as a tumor suppressor Exp Cell Res 264 185 192 1:CAS:528:DC%2BD3MXhsFOhur8%3D 10.1006/excr.2000.5134 11237533
7. HU Schildhaus I Krockel H Lippert P Malfertheiner A Roessner R Schneider-Stock 2005 Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach Int J Oncol 26 1493 1500 1:CAS:528:DC%2BD2MXkvFyrtLw%3D 15870861
8. T Waki G Tamura M Sato M Terashima S Nishizuka T Motoyama 2003 Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia Cancer Sci 94 360 364 1:CAS:528: DC%2BD3sXkslCns7w%3D 10.1111/j.1349-7006.2003.tb01447.x 12824905
9. PJ Issa N Ahuja M Toyota P Bronner TA Brentnall 2001 Accelerated age-related CpG island methylation in ulcerative colitis Cancer Res 61 3573 3577 1:CAS:528:DC%2BD3MXjsFCgtLw%3D 11325821
10. M Velicescu DJ Weisenberger FA Gonzales YC Tsai CT Nguyen PA Jones 2002 Cell division is required for de novo methylation of CpG islands in bladder cancer cells Cancer Res 62 2378 2384 1:CAS:528:DC%2BD38Xjt1ejurY%3D 11956100
11. CJ Sherr 1996 Cancer cell cycles Science 274 1672 1677 1:CAS:528:DyaK28XntlyktLs%3D 10.1126/science.274.5293.1672 8939849
12. W Jiang SM Kahn P Zhou YJ Zhang AM Cacace AS Infante S Doi RM Santella IB Weinstein 1993 Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression Oncogene 8 3447 3457 1:CAS:528:DyaK2cXltFCiug%3D%3D 8247550
13. DE Quelle RA Ashmun SA Shurtleff JY Kato D Bar-Sagi MF Roussel CJ Sherr 1993 Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts Genes Dev 7 1559 1571 1:CAS:528:DyaK3sXmtVSmurw%3D 10.1101/gad.7.8.1559 8339933
14. D Resnitzky 1995 Reed SI Different roles for cyclins D1 and E in regulation of the G1-to-S transition Mol Cell Biol 15 3463 3469 1:CAS:528:DyaK2MXmsVCmu74%3D 7791752
15. AI Robles F Larcher RB Whalin R Murillas E Richie IB Gimenez-Conti JL Jorcano CJ Conti 1996 Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia Proc Natl Acad Sci USA 93 7634 7638 1:CAS:528:DyaK28XksFSrsLw%3D 10.1073/pnas.93.15.7634 8755527
16. ER Sauter UC Yeo A von Stemm W Zhu S Litwin DS Tichansky G Pistritto M Nesbit D Pinkel M Herlyn BC Bastian 2002 Cyclin D1 is a candidate oncogene in cutaneous melanoma Cancer Res 1 3200 3206
17. JC Lung JS Chu JC Yu CT Yue YL Lo CY Shen CW Wu 2002 Aberrant expression of cell-cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability Genes Chromosomes Cancer 34 276 284 1:CAS:528: DC%2BD38XltVSltb4%3D 10.1002/gcc.10072 12007188
18. L Moonen F Ong M Gallee M Verheij S Horenblas AA Hart H Bartelink 2001 Apoptosis, proliferation and p53, cyclin D1, and retinoblastoma gene expression in relation to radiation response in transitional cell carcinoma of the bladder Int J Radiat Oncol Biol Phys 49 1305 1310 1:CAS:528:DC%2BD3MXisVWntrY%3D 11286838
19. AR Sepulveda H Tao E Carloni J Sepulveda DY Graham LE Peterson 2002 Screening of gene expression profiles in gastric epithelial cells induced by Helicobacter pylori using microarray analysis Aliment Pharmacol Ther 16 Suppl 2 145 157 1:CAS:528:DC%2BD38XjslCqsLo%3D 10.1046/j.1365-2036.16.s2.4.x 11966535
20. Y Hirata S Maeda Y Mitsuno M Akanuma Y Yamaji K Ogura H Yoshida Y Shiratori M Omata 2001 Helicobacter pylori activates the cyclin D1 gene through mitogen-activated protein kinase pathway in gastric cancer cells Infect Immun 69 3965 3971 1:CAS:528:DC%2BD3MXjvFyqsrs%3D 10.1128/IAI.69.6.3965-3971.2001 11349065
21. N Arber MD Gammon H Hibshoosh JA Britton Y Zhang JB Schonberg H Roterdam I Fabian PR Holt IB Weinstein 1999 Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach Hum Pathol 30 1087 1092 1:CAS:528:DyaK1MXmvV2hs7s%3D 10.1016/S0046-8177(99)90227-7 10492044
22. G Udhayakumar V Jayanthi N Devaraj H Devaraj 2007 Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclin D1 in H. pylori-induced gastric cancer Mol Carcinog 46 807 817 1:CAS:528:DC%2BD2sXhtFaiur3J 10.1002/mc.20311 17393422
23. GF Yang CS Deng YY Xiong LL Gong BC Wang J Luo 2004 Expression of nuclear factor-kappa B and target genes in gastric precancerous lesions and adenocarcinoma: association with Helicobacter pylori cagA (+) infection World J Gastroenterol 10 491 496 1:CAS:528:DC%2BD2cXislaltbw%3D 14966904
24. DC Betticher N Thatcher HJ Altermatt P Hoban WD Ryder J Heighway 1995 Alternate splicing produces a novel cyclin D1 transcript Oncogene 11 1005 1011 1:CAS:528:DyaK2MXosVyqsrw%3D 7675441
25. DJ Simpson AA Fryer AB Grossman JA Wass M Pfeifer JM Kros RN Clayton WE Farrell 2001 Cyclin D1 (CCND1) genotype is associated with tumour grade in sporadic pituitary adenomas Carcinogenesis 22 1801 1807 1:CAS:528: DC%2BD3MXosV2msLY%3D 10.1093/carcin/22.11.1801 11698342
26. SL Holley G Parkes C Matthias U Bockmuhl V Jahnke K Leder RC Strange AA Fryer PR Hoban 2001 Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neck Am J Pathol 159 1917 1924 1:CAS:528:DC%2BD3MXoslarurg%3D 11696452
27. S Kong CI Amos R Luthra PM Lynch B Levin ML Frazier 2000 Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer Cancer Res 60 249 251 1:CAS:528:DC%2BD3cXhtVahsrs%3D 10667569
28. L Wang T Habuchi T Takahashi K Mitsumori T Kamoto Y Kakehi H Kakinuma K Sato A Nakamura O Ogawa T Kato 2002 Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer Carcinogenesis 23 257 264 10.1093/carcin/23.2.257 11872630
29. KK Dhar K Branigan RE Howells C Musgrove PW Jones RC Strange AA Fryer CW Redman PR Hoban 1999 Prognostic significance of cyclin D1 gene (CCND1) polymorphism in epithelial ovarian cancer Int J Gynecol Cancer 9 342 347 10.1046/j.1525-1438.1999.99048.x 11240791
30. W Guo Z Dong Z Chen Z Yang D Wen G Kuang Y Guo B Shan 2009 Aberrant CpG island hypermethylation of RASSF1A in gastric cardia adenocarcinoma Cancer Invest 27 459 465 1:CAS:528:DC%2BD1MXkt1yisrk%3D 10.1080/07357900802620828 19160099
31. S Ogino K Nosho N Irahara, et al. 2009 A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases Clin Cancer Res 15 4431 4438 1:CAS:528:DC%2BD1MXnvFajtrk%3D 10.1158/1078-0432.CCR-08-3330 19549773
32. T Liu Y Niu Y Feng R Niu Y Yu A Lv Y Yang 2008 Methylation of CpG islands of p16(INK4a) and cyclin D1 overexpression associated with progression of intraductal proliferative lesions of the breast Hum Pathol 39 1637 1646 1:CAS:528:DC%2BD1cXht1Kns7jP 10.1016/j.humpath.2008.04.001 18657295
33. P Lauren 1965 The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification Acta Pathol Microbiol Scand 64 31 49 1:STN:280: DyaF2M7isFenug%3D%3D 14320675
34. M Esteller S Tortola M Toyota G Capella MA Peinado SB Baylin JG Herman 2000 Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status Cancer Res 60 129 133 1:CAS:528:DC%2BD3cXnt1aguw%3D%3D 10646864
35. JG Herman JR Graff S Myöhänen BD Nelkin SB Baylin 1996 Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands Proc Natl Acad Sci USA 93 9821 9826 1:CAS:528:DyaK28XlsFeht7Y%3D 10.1073/pnas.93.18.9821 8790415
36. RA Katzenellenbogen SB Baylin JG Herman 1999 Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies Blood 93 4347 4353 1:CAS:528:DyaK1MXjvVGrtLc%3D 10361133
37. JA McKay JJ Douglas VG Ross S Curran GI Murray J Cassidy HL McLeod 2000 Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen colorectal initiative Int J Cancer 88 77 81 1:CAS:528: DC%2BD3cXmslSntLY%3D 10.1002/1097-0215(20001001)88:1<77::AID-IJC12>3.0. CO;2-O 10964085
38. GH Kang HJ Lee KS Hwang S Lee JH Kim JS Kim 2003 Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation Am J Pathol 163 1551 1556 1:CAS:528:DC%2BD3sXotlegt7Y%3D 14507661
39. T Maekita K Nakazawa M Mihara T Nakajima K Yanaoka M Iguchi K Arii A Kaneda T Tsukamoto M Tatematsu G Tamura D Saito T Sugimura M Ichinose T Ushijima 2006 High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk Clin Cancer Res 12 989 995 1:CAS:528:DC%2BD28XhtFehsr0%3D 10.1158/1078-0432.CCR-05- 2096 16467114
40. T Tahara T Arisawa T Shibata, et al. 2006 Increased number of methylated CpG islands correlates with Helicobacter pylori infection, histological and serological severity of chronic gastritis Eur J Gastroenterol Hepatol 21 613 619 10.1097/MEG.0b013e32830e28b2
41. JP Issa 2000 GpG-island methylation in aging and cancer Curr Top Microbiol Immunol 249 101 118 1:CAS:528:DC%2BD3cXis1ykuro%3D 10802941
42. T Meyer-ter-Vehn A Covacci M Kist HL Pahl 2000 Helicobacter pylori activates mitogen-activated protein kinase cascades and induces expression of the proto-oncogenes c-fos and c-jun J Biol Chem 275 16064 16072 1:CAS:528:DC%2BD3cXjvFaitrs%3D 10.1074/jbc.M000959200 10747974
43. J Zhang Y Li R Wang D Wen M Sarbia G Kuang M Wu L Wei M He L Zhang S Wang 2003 Association of cyclin D1 (G870A) polymorphism with susceptibility to esophageal and gastric cardiac carcinoma in a northern Chinese population Int J Cancer 105 281 284 1:CAS:528:DC%2BD3sXjt12mt7k%3D 10.1002/ijc.11067 12673692
44. JH Song CJ Kim YG Cho YK Park SW Nam NJ Yoo JY Lee WS Park 2007 Association of cyclin D1 G870A polymorphism with susceptibility to gastric cancers in Korean male patients Neoplasma 54 235 239 1:CAS:528: DC%2BD2sXlvF2ls7s%3D 17447856
45. T Tahara T Shibata H Yamashita I Hirata T Arisawa 2008 Effect of cyclin D1 (CCND1) polymorphism on gastric premalignant condition Clin Chem Lab Med 46 1696 1701 1:CAS:528:DC%2BD1MXns1CqsA%3D%3D 10.1515/CCLM.2008.340 19055446
46. H Sawa TA Ohshima H Ukita H Murakami Y Chiba H Kamada M Hara I Saito 1998 Alternatively spliced forms of cyclin D1 modulate entry into the cell cycle in an inverse manner Oncogene 16 1701 1712 1:CAS:528:DyaK1cXisVKjtL4%3D 10.1038/sj.onc.1201691 9582018
47. Y Hosokawa M Gadd AP Smith FC Koerner EV Schmidt A Arnold 1997 Cyclin D1 (PRAD1) alternative transcript b: full-length cDNA cloning and expression in breast cancers Cancer Lett 113 123 130 1:CAS:528:DyaK2sXht1Khsbk%3D 10.1016/S0304-3835(97)04605-3 9065811
48. R Catarino D Pereira E Breda A Coelho A Matos C Lopes R Medeiros 2008 Oncogenic virus-associated neoplasia: a role for cyclin D1 genotypes influencing the age of onset of disease? Biochem Biophys Res Commun 370 118 122 1:CAS:528:DC%2BD1cXks1Kisrk%3D 10.1016/j.bbrc.2008.03.039 18355450