Lower prevalence of human immunodeficiency virus type 1 Brazilian subtype B found in Northeastern Brazil with slower progression to AIDS

AIDS Research and Human Retroviruses

Volumn 26, Issue 11, 2010, Pages 1249-1254

  Araujo, Adriano Fernando ^a   Brites, Carlos ^b   Monteiro Cunha, Joana ^a   Santos, Luciane Amorim ^a   Galvao Castro, Bernardo ^a,c   Alcantara, Luiz Carlos Junior ^a,c,d  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c Bahia Foundation for Science Development   (Brazil)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AMINO ACID SEQUENCE; ARTICLE; BRAZIL; DISEASE COURSE; DNA SEQUENCE; ENVELOPE GENE; FEMALE; GENE SEQUENCE; GROUP SPECIFIC ANTIGEN GENE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS PREVALENCE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; VIRUS CLASSIFICATION; VIRUS GENOME; VIRUS RECOMBINANT; VIRUS STRAIN;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; BRAZIL; CLUSTER ANALYSIS; DISEASE PROGRESSION; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; FEMALE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENOTYPE; HIV-1; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PHYLOGENY; PREVALENCE; RECEPTORS, HIV; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; VIRUS INTERNALIZATION;

EID: 78649255044     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2010.0068     Document Type: Article

References (16)

1. Bastos FI, Cáceres C, Galvão J, Veras MA, and Castilho EA: AIDS in Latin America: Assessing the current status of the epidemic and the ongoing response. Int J Epidemiol 2008;37:729-737.
2. Morgado MG, Guimarães ML, and Galvão-Castro B: HIV-1 polymorphism: A challenge for vaccine development. A review. Mem Inst Oswaldo Cruz 2002;97:143-150.
3. Potts KE, Kalish ML, Lott T, et al.: Genetic heterogeneity of the V3 region of the HIV-1 envelope glycoprotein in Brazil. Brazilian Collaborative AIDS Research Group. AIDS 1993;7:1191-1197.
4. Morgado MG, Sabino EC, Sphaer EG, et al.: V3 region polymorphisms in HIV-1 from Brazil: Prevalence of subtype B strains divergent from North American/European prototypes and detection of subtype F. AIDS Res Hum Retroviruses 1994;10:569-576.
5. De Brito A, Komninakis SC, Novoa P, et al.: Women infected with HIV type 1 Brazilian variant, subtype B (B'-GWGR motif) have slower progression to AIDS, compared with patients infected with subtype B (B-GPGR motif). Clin Infect Dis 2006;43:1476-1481.
6. Edgar RC. MUSCLE: A multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 2004;5:113-132.
7. Nicholas KB, Nicholas Jr HB, and Deerfield II DW: GeneDoc: Analysis and visualization of genetic variation. Embnet News 1997;4:1-4.
8. Swofford D. PAUP 4.0: Phylogenetic analysis using parsimony (and other methods), 8 4.0b2a. Sunderland, MA, USA: Sinauer Associates, Inc. 1999.
9. Posada D and Krandall KA: MODELTEST: Testing the model of DNA substitution. Bioinformatics 1998;14:817-818.
10. Salminen MO, Carr JK, Burke DS, and McCutchan FE: Identification of breakpoints in intergenotypic recombinants of HIV type 1 by bootscanning. AIDS Res Hum Retrovir 1995;11:1423-1425.
11. Sing T, Low AJ, Beerenwinkel N, et al.: Predicting HIV coreceptor usage based on genetic and clinical covariates. Antiviral Therapy 2007;12:1097-1106.
12. Korber B: HIV Signature and Sequence Variation Analysis. In: Computational Analysis of HIV Molecular Sequences. (Allen G. Rodrigo and Gerald H. Learn, eds). Dordrecht, Netherlands: Kluwer Academic Publishers. 2000, pp. 55-72.
13. Mindell DP: Positive selection and rates of evolution in immunodeficiency viruses from humans and chimpanzees. Proc Natl Acad Sci USA 1996;93:3284-3288.
14. Monteiro JP, Alcantara LC, de Oliveira T, et al.: Genetic variability of human immunodeficiency virus-1 in Bahia state, Northeast, Brazil: High diversity of HIV genotypes. J Med Virol 2009;81:391-399.
15. Brennan CA, Brites C, Bodelle P, et al.: HIV-1 strains identified in Brazilian blood donors: Significant prevalence of B/F1 recombinants. AIDS Res Hum Retroviruses 2007;11:1434-1441.
16. Diaz RS, Leal E, Sanabani S, et al.: Selective regimes and evolutionary rates of HIV-1 subtype B V3 variants in the Brazilian epidemic. Virology 2008;38:184-193.