Solution calorimetry as an alternative approach for dissolution testing of nanosuspensions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 3, 2010, Pages 507-513

  Kayaert, P ^a   Li, B ^b   Jimidar, I ^b   Rombaut, P ^a   Ahssini, F ^a   Van den Mooter, G ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Cinnarizine; Dissolution rate; Nanosuspensions; Naproxen; Solution calorimetry

Indexed keywords

CINNARIZINE; COMPOUND A; HYDROXYPROPYLMETHYLCELLULOSE; NANOCRYSTAL; NAPROXEN; NEW DRUG; TOCOFERSOLAN; UNCLASSIFIED DRUG;

ARTICLE; CALIBRATION; CALORIMETRY; CONTROLLED STUDY; DRUG SOLUBILITY; METHODOLOGY; SOLUTION CALORIMETRY; SUSPENSION; TEMPERATURE MEASUREMENT; TEMPERATURE SENSITIVITY;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; CALORIMETRY; DRUG DELIVERY SYSTEMS; EXCIPIENTS; NANOPARTICLES; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; SOLUTIONS; SUSPENSIONS; TRANSITION TEMPERATURE;

EID: 78549278031     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.09.009     Document Type: Article

References (9)

1. Muller R.H., Möschwitzer J., Bushrab F.F. Manufacturing of nanoparticles by milling and homogenization techniques. Drugs and the Pharmaceutical Sciences 2006, vol. 159:21-51. Taylor and Francis Group, LLC, NY. R.B. Gupta, U.B. Kompella (Eds.).
2. Kocbek P., Baumgartner S., Kristl J. Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs. Int. J. Pharm. 2006, 312:179-186.
3. Lai F., Sinico C., Ennas G., Marongiu F., Marongiu G., Fadda A.M. Diclofenac nanosuspensions: influence of preparation procedure and crystal form on drug dissolution behavior. Int. J. Pharm. 2009, 373:124-132.
4. Shikov A.N., Pozharitskaya O.N., Miroshnyk I., Mirza S., Urakova I.N., Hirsjärvi S., Makarov V.G., Heinämäki J., Yliruusi J., Hiltunen R. Nanodispersions of taxifolin: impact of solid-state properties on dissolution behavior. Int. J. Pharm. 2009, 377:148-152.
5. Dong Y., Ng K.W., Shen S., Kim S., Tan R.B.H. Preparation and characterization of spironolactone nanoparticles by antisolvent precipitation. Int. J. Pharm. 2009, 375:44-88.
6. Chaubal M.V., Popescu C. Conversion of nanosuspensions into dry powders by spray drying: a case study. Pharm. Res. 2008, 25:2302-2308.
7. Peeters K., De Maesschalck R., Bohets H., Vanhoutte K., Nagels L. In situ dissolution testing using potentiometric sensors. Eur. J. Pharm. Sci. 2008, 34:243-249.
8. Sunner S. Basic principles of combustion calorimetry. Combustion Calorimetry 1979, vol. 1. Pergamon, Oxford. S. Sunner, M. Mansson (Eds.).
9. Yff B.T.S., Royall P.G., Brown M.B., Martin G.P. An investigation of calibration methods for solution calorimetry. Int. J. Pharm. 2004, 269:361-372.