Animal insulin therapy induces a biased insulin antibody response that persists for years after introduction of human insulin

Acta Diabetologica

Volumn 47, Issue 2, 2010, Pages 131-135

  Oak, Shilpa ^a   Phan, Thanh Hien Thi ^a   Gilliam, Lisa K ^a   Hirsch, Irl B ^a   Hampe, Christiane S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Antibody epitopes; Insulin antibodies; Radio ligand binding assay; Type 1 diabetes

Indexed keywords

BOVINE INSULIN; EPITOPE; INSULIN ANTIBODY; PIG INSULIN; RECOMBINANT HUMAN INSULIN; ANTIDIABETIC AGENT; AUTOANTIBODY; INSULIN;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY SCREENING; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DISEASE DURATION; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ADOLESCENT; ANIMAL; ANTIBODY PRODUCTION; BLOOD; IMMUNOLOGY; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; RADIOASSAY;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIBODY FORMATION; AUTOANTIBODIES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN ANTIBODIES; MALE; MIDDLE AGED; RADIOLIGAND ASSAY; YOUNG ADULT;

EID: 77952770755     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-009-0135-2     Document Type: Article

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