-
1
-
-
33751413608
-
Aging and the ubiquitinome: Traditional and non-traditional functions of ubiqutin in aging cells and tissues
-
Grillari J, Katinger H, Voglaue R. Aging and the ubiquitinome: Traditional and non-traditional functions of ubiqutin in aging cells and tissues. Exp Geront 41: 1067-1079 (2006).
-
(2006)
Exp Geront
, vol.41
, pp. 1067-1079
-
-
Grillari, J.1
Katinger, H.2
Voglaue, R.3
-
3
-
-
9744222883
-
Protein quality control in Alzheimer's disease by the ubiquitin proteasome system
-
De Vrij FM, Fischer DF, van Leeuwen FW, Hol EM. Protein quality control in Alzheimer's disease by the ubiquitin proteasome system. Prog Neurobiol 74: 249-270 (2004).
-
(2004)
Prog Neurobiol
, vol.74
, pp. 249-270
-
-
de Vrij, F.M.1
Fischer, D.F.2
van Leeuwen, F.W.3
Hol, E.M.4
-
4
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH and Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428 (2002).
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
5
-
-
0032190090
-
The ubiquitin pathway in Parkinsons disease
-
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E, et al. The ubiquitin pathway in Parkinsons disease. Nature 395: 451-452 (1998).
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
-
6
-
-
33644859083
-
The ubiquitin proteolytic system: From a vague idea, through basic mechanisms, and onto human diseases and drug targeting
-
Ciechanover A. The ubiquitin proteolytic system: from a vague idea, through basic mechanisms, and onto human diseases and drug targeting. Neurology 66: 7-19 (2006).
-
(2006)
Neurology
, vol.66
, pp. 7-19
-
-
Ciechanover, A.1
-
7
-
-
35748959676
-
The ubiquitin-proteasome pathway in health and disease of the nervous system
-
Hegde AN, Upadhya SC. The ubiquitin-proteasome pathway in health and disease of the nervous system. Trends Neurosci 30: 587-595 (2007).
-
(2007)
Trends Neurosci
, vol.30
, pp. 587-595
-
-
Hegde, A.N.1
Upadhya, S.C.2
-
9
-
-
0034915764
-
Mechanisms underlying ubiquitiniation
-
Pickart CM. Mechanisms underlying ubiquitiniation. Ann Rev Biochem 70: 503-533 (2001).
-
(2001)
Ann Rev Biochem
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
10
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser M. Ubiquitin-dependent protein degradation. Ann Rev Genet 30: 405-439 (1996).
-
(1996)
Ann Rev Genet
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
11
-
-
0034065822
-
Ubiquitin-mediated proteolysis: Biological regulation via destruction
-
Ciechanover A, Orian A, Schwartz AL. Ubiquitin-mediated proteolysis: biological regulation via destruction. BioEssays 22: 442-451 (2000).
-
(2000)
BioEssays
, vol.22
, pp. 442-451
-
-
Ciechanover, A.1
Orian, A.2
Schwartz, A.L.3
-
13
-
-
0028013249
-
Alzheimer disease: Correlation of cerebro-spinal fluid and brain ubiquitin levels
-
Kudo T, Iqbal K, Ravid R, Swaab DF, Grundke-Iqbal I. Alzheimer disease: correlation of cerebro-spinal fluid and brain ubiquitin levels. Brain Res 639: 1-7 (1994).
-
(1994)
Brain Res
, vol.639
, pp. 1-7
-
-
Kudo, T.1
Iqbal, K.2
Ravid, R.3
Swaab, D.F.4
Grundke-Iqbal, I.5
-
14
-
-
0034131044
-
Impaired proteasome function in Alzheimer's disease
-
Keller JN, Hanni KB, Markesbery WR. Impaired proteasome function in Alzheimer's disease. J Neurochem 75: 436-439 (2000).
-
(2000)
J Neurochem
, vol.75
, pp. 436-439
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
15
-
-
0037012031
-
Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging
-
Ponnappan U. Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging. Exp Gerontol 37: 359 (2002).
-
(2002)
Exp Gerontol
, vol.37
, pp. 359
-
-
Ponnappan, U.1
-
16
-
-
34249784822
-
Inflammatory markers and the risk of Alzheimer disease: The Framingham Study
-
Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, et al. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology 68: 1902-1908 (2007).
-
(2007)
Neurology
, vol.68
, pp. 1902-1908
-
-
Tan, Z.S.1
Beiser, A.S.2
Vasan, R.S.3
Roubenoff, R.4
Dinarello, C.A.5
Harris, T.B.6
-
17
-
-
0141638441
-
Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity
-
Song S, Kim SY, Hong YM, Jo DG, Lee JY, Shim SM, et al. Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity. Mol Cell 12: 553-563 (2003).
-
(2003)
Mol Cell
, vol.12
, pp. 553-563
-
-
Song, S.1
Kim, S.Y.2
Hong, Y.M.3
Jo, D.G.4
Lee, J.Y.5
Shim, S.M.6
-
18
-
-
70449362319
-
Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimers disease
-
Epub ahead of print
-
Marksteiner J, Kemmler G, Weiss EM, Knauss G, Ullrich C, Mechteriakov S, et al. Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimers disease. Neurobiol Aging [Epub ahead of print] (2009).
-
(2009)
Neurobiol Aging
-
-
Marksteiner, J.1
Kemmler, G.2
Weiss, E.M.3
Knauss, G.4
Ullrich, C.5
Mechteriakov, S.6
-
19
-
-
67349183939
-
Glycogen-synthase kinase-3 beta is decreased in peripheral blood mononuclear cells of patients with mild cognitive impairment
-
Marksteiner J, Humpel C. Glycogen-synthase kinase-3 beta is decreased in peripheral blood mononuclear cells of patients with mild cognitive impairment. Exp Gerontol 44: 370-1 (2009).
-
(2009)
Exp Gerontol
, vol.44
, pp. 370-371
-
-
Marksteiner, J.1
Humpel, C.2
-
20
-
-
51949086357
-
Beta-amyloid expression, release and extracellular deposition in aged rat brain slices
-
Marksteiner J, Humpel C. Beta-amyloid expression, release and extracellular deposition in aged rat brain slices. Mol Psychiatry 1-14 (2008).
-
(2008)
Mol Psychiatry
, pp. 1-14
-
-
Marksteiner, J.1
Humpel, C.2
-
21
-
-
33644810390
-
Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance
-
Klimaschewski L, Hausott B, Ingorokva S, Pfaller K. Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance. J Neurochem 96: 1708-1717 (2006).
-
(2006)
J Neurochem
, vol.96
, pp. 1708-1717
-
-
Klimaschewski, L.1
Hausott, B.2
Ingorokva, S.3
Pfaller, K.4
-
22
-
-
33645013396
-
Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease
-
Blandini F, Sinforiani E, Pacchetti C, Samuele A, Bazzini E, Zanganglia R, et al. Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease. Neurology 66: 529-534 (2006).
-
(2006)
Neurology
, vol.66
, pp. 529-534
-
-
Blandini, F.1
Sinforiani, E.2
Pacchetti, C.3
Samuele, A.4
Bazzini, E.5
Zanganglia, R.6
-
23
-
-
33744767744
-
Protein ubiquitination, degradation and the proteasome in neurodegerative disorders: No clear evidence for a significant pathogenetic role of proteasome failure in Alzheimers disease and related disorders
-
Schmitt HP. Protein ubiquitination, degradation and the proteasome in neurodegerative disorders: no clear evidence for a significant pathogenetic role of proteasome failure in Alzheimers disease and related disorders. Med Hypotheses 67: 311-317 (2006).
-
(2006)
Med Hypotheses
, vol.67
, pp. 311-317
-
-
Schmitt, H.P.1
-
24
-
-
0001521232
-
Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains
-
Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci USA 84: 3033-3036 (1987).
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3033-3036
-
-
Perry, G.1
Friedman, R.2
Shaw, G.3
Chau, V.4
-
25
-
-
0030771902
-
Ubiquitin (Ub) interacts non-covalently with Alzheimer amyloid precursor protein (betaPP): Isolation of Ub-betaPP conjugates from brain extracts
-
Master E, Chan SL, Ali-Khan Z. Ubiquitin (Ub) interacts non-covalently with Alzheimer amyloid precursor protein (betaPP): isolation of Ub-betaPP conjugates from brain extracts. Neuroreport 8: 2781-2786 (1997).
-
(1997)
Neuroreport
, vol.8
, pp. 2781-2786
-
-
Master, E.1
Chan, S.L.2
Ali-Khan, Z.3
-
26
-
-
0034667727
-
Defective ubiquitination of cerebral proteins in Alzheimer's disease
-
López Salon M, Morelli L, Castaño EM, Soto EF, Pasquini JM. Defective ubiquitination of cerebral proteins in Alzheimer's disease. J Neurosci Res 62: 302-310 (2000).
-
(2000)
J Neurosci Res
, vol.62
, pp. 302-310
-
-
López Salon, M.1
Morelli, L.2
Castaño, E.M.3
Soto, E.F.4
Pasquini, J.M.5
-
27
-
-
0036630340
-
Are peripheral blood cells from patients with Alzheimer disease more sensitive to apoptotic stimuli?
-
Bergman M, Salman H, Beloosesky Y, Djaldetti M, Bessler H. Are peripheral blood cells from patients with Alzheimer disease more sensitive to apoptotic stimuli? Alzheimer Dis Assoc Disord 16: 156-160 (2002).
-
(2002)
Alzheimer Dis Assoc Disord
, vol.16
, pp. 156-160
-
-
Bergman, M.1
Salman, H.2
Beloosesky, Y.3
Djaldetti, M.4
Bessler, H.5
-
28
-
-
48749090016
-
Novel systemic markers for patients with Alzheimer disease? - a pilot study
-
Kassner SS, Bonaterra GA, Kaiser E, Hildebrandt W, Metz J, Schröder J, et al. Novel systemic markers for patients with Alzheimer disease? - a pilot study. Curr Alzheimer Res 5: 358-366 (2008).
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 358-366
-
-
Kassner, S.S.1
Bonaterra, G.A.2
Kaiser, E.3
Hildebrandt, W.4
Metz, J.5
Schröder, J.6
-
29
-
-
39649085837
-
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
-
Franceschi C. Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr Rev 65: 173-176 (2007).
-
(2007)
Nutr Rev
, vol.65
, pp. 173-176
-
-
Franceschi, C.1
-
30
-
-
58149499431
-
Inflammaging as a prodrome to Alzheimer's disease
-
Giunta B, Fernandez F, Nikolic WV, Obregon D, Rrapo E, Town T, et al. Inflammaging as a prodrome to Alzheimer's disease. J Neuroinflam 5: 51 (2008).
-
(2008)
J Neuroinflam
, vol.5
, pp. 51
-
-
Giunta, B.1
Fernandez, F.2
Nikolic, W.V.3
Obregon, D.4
Rrapo, E.5
Town, T.6
-
31
-
-
68649118090
-
A critical evaluation of the ubiquitin-proteasome system in Parkinsońs disease
-
Cook C, Petrucelli L. A critical evaluation of the ubiquitin-proteasome system in Parkinsońs disease. Biochim Biophys Acta 1792: 664-675 (2009).
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 664-675
-
-
Cook, C.1
Petrucelli, L.2
-
32
-
-
3042794162
-
Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
-
McNaught KS, Perl DP, Brownell A, Olanow CW. Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol 56: 149-162 (2004).
-
(2004)
Ann Neurol
, vol.56
, pp. 149-162
-
-
McNaught, K.S.1
Perl, D.P.2
Brownell, A.3
Olanow, C.W.4
-
33
-
-
67349256160
-
Ubiquitin-like protein activation by E1 enzymes: The apex for downstream signalling pathways
-
Schulman BA, Harper JW. Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways. Nature Rev 10: 319-331 (2009).
-
(2009)
Nature Rev
, vol.10
, pp. 319-331
-
-
Schulman, B.A.1
Harper, J.W.2
-
35
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL. Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899 (2003).
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
36
-
-
4544266973
-
CSF biomarkers for mild cognitive impairment
-
Blennow K. CSF biomarkers for mild cognitive impairment. J Intern Med 256: 224-234 (2004).
-
(2004)
J Intern Med
, vol.256
, pp. 224-234
-
-
Blennow, K.1
-
37
-
-
25144513449
-
CSF biomarkers for Alzheimeŕs disease: Use in early diagnosis and evaluation of drug treatment
-
Blennow K. CSF biomarkers for Alzheimeŕs disease: use in early diagnosis and evaluation of drug treatment. Exp Rev Mol Diagn 5: 661-672 (2005).
-
(2005)
Exp Rev Mol Diagn
, vol.5
, pp. 661-672
-
-
Blennow, K.1
-
38
-
-
67649516619
-
Peripheral biomarkers in dementia and Alzheimers disease
-
Michael S. Ritsner Ed., Springer; ISBN: 978-1-4020-9837-6
-
Humpel C, Marksteiner J. Peripheral biomarkers in dementia and Alzheimers disease. In: "The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes, Volume III: Metabolic and Peripheral Biomarkers", Michael S. Ritsner Ed., Springer; ISBN: 978-1-4020-9837-6 (2009).
-
(2009)
The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes, Volume III: Metabolic and Peripheral Biomarkers
-
-
Humpel, C.1
Marksteiner, J.2
-
39
-
-
35948933394
-
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
-
Ray S, Britschgi M, Herbert C, Takedu-Uchimura Y, Boxer A, Blennow K, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 13: 1359-1362 (2007).
-
(2007)
Nat Med
, vol.13
, pp. 1359-1362
-
-
Ray, S.1
Britschgi, M.2
Herbert, C.3
Takedu-Uchimura, Y.4
Boxer, A.5
Blennow, K.6
|