Clearance kinetics of fullerene C60 nanoparticles from rat lungs after intratracheal C60 instillation and inhalation C60 exposure

Toxicological Sciences

Volumn 118, Issue 2, 2010, Pages 564-573

  Shinohara, Naohide ^a   Nakazato, Tetsuya ^a   Tamura, Moritaka ^a   Endoh, Shigehisa ^a   Fukui, Hiroko ^a   Morimoto, Yasuo ^b   Myojo, Toshihiko ^b   Shimada, Manabu ^c   Yamamoto, Kazuhiro ^a   Tao, Hiroaki ^a   Yoshida, Yasukazu ^a   Nakanishi, Junko ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

2 compartment model; C60; Clearance; Fullerene; Inhalation exposure; Intratracheal instillation; Nano material; Nanoparticle

Indexed keywords

FULLERENE C60; FULLERENE DERIVATIVE; NANOPARTICLE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CLEARANCE; EXPOSURE; KINETICS; LIVER; LUNG; MALE; NONHUMAN; PARTICLE SIZE; QUALITY CONTROL; RAT;

ADMINISTRATION, INHALATION; AIR POLLUTANTS; ANIMALS; BODY BURDEN; BRAIN; CARBON DIOXIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FULLERENES; INTUBATION, INTRATRACHEAL; LIMIT OF DETECTION; LIVER; LUNG; MACROPHAGES, ALVEOLAR; MALE; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; PHAGOSOMES; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 78549270459     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq288     Document Type: Article

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