Does Arkadia contribute to TGF-β1-induced IgA expression through up-regulation of Smad signaling in IgA nephropathy?

International Urology and Nephrology

Volumn 42, Issue 3, 2010, Pages 719-722

  Li, Xiao Zhao ^a   Feng, Jun Tao ^a   Hu, Cheng Ping ^a   Chen, Ze Qi ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Arkadia; IgA; IgA nephropathy; Smad signaling; TGF 1

Indexed keywords

ARKADIA; IMMUNOGLOBULIN A; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 78549257790     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-009-9682-2     Document Type: Review

References (27)

1. FP Schena 1990 A retrospective analysis of the natural history of primary IgA nephropathy worldwide Am J Med 9 2 209 225
2. J Wada H Sugiyama H Makino 2003 Pathogenesis of IgA nephropathy Semin Nephrol 23 6 556 563 10.1053/S0270-9295(03)00134-7 14631563
3. MB Sporn AB Roberts 1992 Transforming growth factor-beta: recent progress and new challenges J Cell Biol 119 5 1017 1021 10.1083/jcb.119.5.1017 1332976
4. D Del Prete G Gambaro A Lupo, et al. 2003 Precocious activation of genes of the renin-angiotensin system and the fibrogenic cascade in IgA glomerulonephritis Kidney Int 64 1 149 159 10.1046/j.1523-1755.2003.00065.x 12787405 (Pubitemid 36714167)
5. JC Leung LY Chan AW Tsang, et al. 2004 Anti-macrophage migration inhibitory factor reduces transforming growth factor-beta 1 expression in experimental IgA nephropathy Nephrol Dial Transplant 19 8 1976 1985 10.1093/ndt/gfh323 15187193 (Pubitemid 39139626)
6. Q Zhong JC Leung LY Chan, et al. 2005 The study of Chinese medicinal herbal formula Shen San Fang in the treatment of experimental IgA nephropathy Am J Chin Med 33 4 613 626 10.1142/S0192415X05003211 16173535 (Pubitemid 41194622)
7. 1 and apoptosis in the progression of glomerulosclerosis in human IgA nephropathy Clin Nephrol 65 6 385 392 16792132
8. WA Border NA Noble 1997 TGF-beta in kidney fibrosis: a target for gene therapy Kidney Int 51 1388 1396 10.1038/ki.1997.190 9150449
9. WA Border NA Noble T Yamamoto, et al. 1992 Antagonists of transforming growth factor-beta: a novel approach to treatment of glomerulonephritis and prevention of glomerulosclerosis Kidney Int 41 3 566 570 10.1038/ki.1992.83 1573830
10. J Stavnezer 1996 Immunoglobulin class switching Curr Opin Immunol 8 2 199 205 10.1016/S0952-7915(96)80058-6 8725943 (Pubitemid 26166985)
11. Y Zhang R Derynck 2000 Transcriptional regulation of the transforming growth factor-beta -inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members J Biol Chem 275 22 16979 16985 10.1074/jbc.M001526200 10748032 (Pubitemid 30398938)
12. DA Kaminski J Stavnezer 2007 Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b Eur J Immunol 37 1 240 251 10.1002/eji.200636645 17163453 (Pubitemid 46128804)
13. SR Park GY Seo AJ Choi, et al. 2005 Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching Eur J Immunol 35 3 946 956 10.1002/eji.200425848 15688346 (Pubitemid 40425550)
14. E Pardali XQ Xie P Tsapogas, et al. 2000 Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes J Biol Chem 275 5 3552 3560 10.1074/jbc.275.5.3552 10652350 (Pubitemid 30083064)
15. DA Lebman FD Lee RL Coffman 1990 Mechanism for transforming growth factor beta and IL-2 enhancement of IgA expression in lipopolysaccharide-stimulated B cell cultures J Immunol 144 3 952 959 2295822
16. PH Kim MF Kagnoff 1990 Transforming growth factor-beta 1 is a costimulator for IgA production J Immunol 144 9 3411 3416 2329276
17. FW Van Ginkel SM Wahl JF Kearney, et al. 1999 Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta1 knockout mice J Immuno l163 4 1951 1957
18. A Moustakas S Souchelnytskyi CH Heldin 2001 Smad regulation in TGF-beta signal transduction J Cell Sci 114 24 4359 4369 11792802
19. SR Park JH Lee PH Kim 2001 Smad3 and Smad4 mediate transforming growth factor-beta1-induced IgA expression in murine B lymphocytes Eur J Immunol 31 6 1706 1715 10.1002/1521-4141(200106)31:6<1706::AID-IMMU1706>3.0.CO;2-Z 11385614 (Pubitemid 32547332)
20. KN Lai SC Tang JY Guh, et al. 2003 Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system J Am Soc Nephrol 14 12 3127 3137 10.1097/01.ASN.0000095639.56212.BF 14638911 (Pubitemid 37509290)
21. Y Kanamaru A Nakao M Mamura, et al. 2001 Blockade of TGF-beta signaling in T cells prevents the development of experimental glomerulonephritis J Immunol 166 4 2818 2823 11160349
22. Y Nagano KJ Mavrakis KL Lee, et al. 2007 Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling J Biol Chem 282 28 20492 20501 10.1074/jbc.M701294200 17510063 (Pubitemid 47100041)
23. KJ Mavrakis RL Andrew KL Lee, et al. 2007 Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover PLoS Biol 5 3 e67 10.1371/journal.pbio.0050067 17341133 (Pubitemid 46422976)
24. L Levy M Howell D Das, et al. 2007 Arkadia activates Smad3/Smad4- dependent transcription by triggering signal-induced SnoN degradation Mol Cell Biol 27 17 6068 6083 10.1128/MCB.00664-07 17591695 (Pubitemid 47326695)
25. FY Liu XZ Li YM Peng, et al. 2007 Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis Am J Nephrol 27 2 176 183 17347560
26. FY Liu XZ Li YM Peng, et al. 2008 Arkadia regulates TGF-beta signaling in renal tubular epithelial to mesenchymal cell transition Kidney Int 73 588 594 10.1038/sj.ki.5002713 18059455 (Pubitemid 351264107)
27. SH Choi GY Seo EH Nam, et al. 2007 Opposing effects of Arkadia and Smurf on TGFbeta1-induced IgA isotype expression Mol Cells 24 2 283 287 17978583