Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 24, 2010, Pages 7337-7340

  Metaferia, Belhu B ^a   Rittler, Matthew ^a   Gheeya, Jinesh S ^a   Lee, Albert ^a   Hempel, Heidi ^a   Plaza, Alberto ^b   Stetler Stevenson, William G ^a   Bewley, Carole A ^b   Khan, Javed ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Aminopeptidase N; Click chemistry; Cyclic peptides; Fluorescence polarization; Targeted delivery

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; ASPARAGINEGLYCYLARGININE; DRUG VEHICLE; PEPTIDE; RESIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS;

ANTIGENS, CD13; CELL LINE, TUMOR; CLICK CHEMISTRY; CYCLIZATION; DRUG CARRIERS; FLUORESCENCE POLARIZATION; HUMANS; PEPTIDES, CYCLIC; PROTEIN BINDING; RESINS, SYNTHETIC;

EID: 78449304271     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.064     Document Type: Article

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24. 6: 594.3225; found 594.3225 ppm.
25. 13: 953.3542; found 953.3522, Δ = -2.1 ppm.