Superstoichiometric binding of L-Phe to phenylalanine hydroxylase from Caenorhabditis elegans: Evolutionary implications

Amino Acids

Volumn 39, Issue 5, 2010, Pages 1463-1475

  Flydal, Marte I ^a   Mohn, Tonje C ^a   Pey, Angel L ^a,b   Siltberg Liberles, Jessica ^a,c   Teigen, Knut ^a   Martinez, Aurora ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF WYOMING   (United States)

Author keywords

Allosterism; Binding stoichiometry; Enzyme regulation; Evolution; Prephenate dehydratase

Indexed keywords

PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PREPHENATE DEHYDRATASE; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CAENORHABDITIS ELEGANS; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STOICHIOMETRY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOCATALYSIS; CAENORHABDITIS ELEGANS; CALORIMETRY; CIRCULAR DICHROISM; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; SEQUENCE ALIGNMENT; STEREOISOMERISM;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 78449299912     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-010-0611-6     Document Type: Article

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