Despite identifying some shared gene associations with human atopic dermatitis the use of multiple dog breeds from various locations limits detection of gene associations in canine atopic dermatitis

Veterinary Immunology and Immunopathology

Volumn 138, Issue 3, 2010, Pages 193-197

  Wood, Shona H ^a,b   Ollier, William E ^a,b   Nuttall, Tim ^a   McEwan, Neil A ^a   Carter, Stuart D ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Association study; Atopic dermatitis; Canine; Human; TSLP receptor

Indexed keywords

DECAPENTAPLEGIC PROTEIN; DECAPENTAPLEGIC PROTEIN 4; FILAGGRIN; MESSENGER RNA; THYMIC STROMAL LYMPHOPOIETIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOPIC DERMATITIS; BREEDING; CANINE ATOPIC DERMATITIS; CONTROLLED STUDY; DOG DISEASE; EXPERIMENTAL DOG; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN ATOPIC DERMATITIS; INPPL1 GENE; JAPAN; MS4A2 GENE; NONHUMAN; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM; UNITED STATES;

ANIMALS; CASE-CONTROL STUDIES; DERMATITIS, ATOPIC; DOG DISEASES; DOGS; GENETIC ASSOCIATION STUDIES; GREAT BRITAIN; HUMANS; JAPAN; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CYTOKINE; SPECIES SPECIFICITY; UNITED STATES;

CANIS FAMILIARIS;

EID: 78449274636     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2010.07.020     Document Type: Article

References (21)

1. Clements D.N., Wood S., Carter S.D., Ollier W.E. Assessment of the quality and quantity of genomic DNA recovered from canine blood samples by three different extraction methods. Research in Veterinary Science 2008, 85(1):74-79.
2. Curwen V., Eyras E., Andrews T.D., Clarke L., Mongin E., Searle S.M., Clamp M. The Ensembl automatic gene annotation system. Genome Research 2004, 14:942-950.
3. DeBoer D.J., Hillier A. The ACVD task force on canine atopic dermatitis (XV): fundamental concepts in clinical diagnosis. Veterinary Immunology and Immunopathology 2001, 81:271-276.
4. Hillier A., DeBoer D.J. The ACVD task force on canine atopic dermatitis (XVII): intradermal testing. Veterinary Immunology and Immunopathology 2001, 81:289-304.
5. Hoffjan S., Epplen T. The genetics of atopic dermatitis: recent findings and future options. Journal of Molecular Medicine 2005, 83:682-692.
6. Lilleberg S.L. In-depth mutation and SNP discovery using DHPLC gene scanning. Current Opinion in Drug Discovery and Development 2003, 6:237-252.
7. Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J., Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E., Alvarez P., Biagi T., Brockman W., Butler J., Chin C.W., Cook A., Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M., Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L., Koepfli K.P., Parker H.G., Pollinger J.P., Searle S.M.J., Sutter N.B., Thomas R., Webber C., Lander E.S. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005, 438:803-819.
8. Merryman-Simpson A.E., Wood S.H., Fretwell N., Jones P.G., McLaren W.M., McEwan N.A., Clements D.N., Carter S.D., Ollier W.E., Nuttall T. Gene (mRNA) expression in canine atopic dermatitis: microarray analysis. Veterinary Dermatology 2008, 19:59-66.
9. Olivry T., Hill P.B. The ACVD task force on canine atopic dermatitis (VIII): is the epidermal lipid barrier defective?. Veterinary Immunology and Immunopathology 2001, 81:215-218.
10. Purcell S., Neale B., Todd-Brown K., Thomas L., Ferreira M.A.R., Bender D., Maller J., Sklar P., de Bakker P.I.W., Daly M.J., Sham P.C. PLINK: a tool set for whole-genome association and population-based linkage analyses. The American Journal of Human Genetics 2007, 81:559-575.
11. Reich D.E., Cargill M., Bolk S., Ireland J., Sabeti P.C., Richter D.J., Lavery T., Kouyoumjian R., Farhadian S.F., Ward R., Lander E.S. Linkage disequilibrium in the human genome. Nature 2001, 411:199-204.
12. Short, A.D., 2006. The genetics of canine diabetes: a candidate gene study. The University of Manchester, Thesis.
13. Sousa C.A., Marsella R. The ACVD task force on canine atopic dermatitis (II): genetic factors. Veterinary Immunology and Immunopathology 2001, 81:153-157.
14. Sutter N.B., Eberle M.A., Parker H.G., Pullar B.J., Kirkness E.F., Kruglyak L., Ostrander E.A. Extensive and breed-specific linkage disequilibrium in Canis familiaris. Genome Research 2004, 14:2388-2396.
15. Tarpataki N., Papa K., Reiczigel J., Vajdovich P., Vorosi K. Prevalence and features of canine atopic dermatitis in Hungary. Acta Veterinaria Hungarica 2006, 54:353-366.
16. Tian C., Gregersen P.K., Seldin M.F. Accounting for ancestry: population substructure and genome-wide association studies. Human Molecular Genetics 2008, 17:R143-R150.
17. The International HapMap Consortium A second generation human haplotype map of over 3.1 million SNPs. Nature 2007, 449:851-861.
18. Vickery B.P. Skin barrier function in atopic dermatitis. Current Opinion in Pediatrics 2007, 19:89-93.
19. Wood S.H., Ke X., Nuttall T., McEwan N., Ollier W.E., Carter S.D. Genome-wide association analysis of canine atopic dermatitis and identification of disease related SNPs. Immunogenetics 2009, 61:765-772.
20. Wood S.H., Clements D.N., Ollier W.E., Nuttall T., McEwan N.A., Carter S.D. Gene expression in canine atopic dermatitis and correlation with clinical severity scores. Journal of Dermatological Science 2009, 55:27-33.
21. Liu Y.-J. Thymic stromal lymphopoietin: master switch for allergic inflammation. The Journal of Experimental Medicine 2006, 203:269-273.