TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation

Journal of Biological Chemistry

Volumn 285, Issue 47, 2010, Pages 37111-37120

  Lau, Alan W ^a   Pringle, Lashon M ^a   Quick, Laura ^a   Riquelme, Daisy N ^a   Ye, Ying ^a   Oliveira, Andre M ^b   Chou, Margaret M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE HOMEOSTASIS; BONE MORPHOGENETIC PROTEINS; CELL TYPES; KEY REGULATORS; MOLECULAR MECHANISM; OSTEOBLAST FUNCTION; OSTEOBLAST MATURATION; OSTEOGENESIS; OVER-EXPRESSION; TRANSCRIPTOME ANALYSIS; UBIQUITIN;

ENDOCRINOLOGY; OSTEOBLASTS; PROTEINS;

BONE;

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN 4; GREMLIN 1 PROTEIN; PROTEINASE; UBIQUITIN SPECIFIC PROTEASE 6; UNCLASSIFIED DRUG;

ANEURYSMAL BONE CYST; ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL MATURATION; CELL TRANSFORMATION; CONTROLLED STUDY; HOMEOSTASIS; MOUSE; NONHUMAN; ONCOGENE; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADP-RIBOSYLATION FACTORS; ALKALINE PHOSPHATASE; ANIMALS; AUTOCRINE COMMUNICATION; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BONE CYSTS, ANEURYSMAL; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CULTURE MEDIA, CONDITIONED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOPEPTIDASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; OSTEOBLASTS; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 78449262528     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.175133     Document Type: Article

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