Inhibition of Helicobacter pylori aminoacyl-tRNA amidotransferase by chloramphenicol analogs

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 22, 2010, Pages 7868-7872

  Balg, Christian ^a   Mieri, Maria De ^b   Huot, Jonathan L ^a   Blais, Sébastien P ^a   Lapointe, Jacques ^a   Chênevert, Robert ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Amidotransferase; Aminoacyl tRNA; Chloramphenicol; GatCAB; Helicobacter pylori; Puromycin; Transamidation

Indexed keywords

1 (4 NITROPHENYL) 2 (METHIONYLSULFONAMIDO) 1,3 PROPANEDIOL; AMINOACYL TRANSFER RNA; CHLORAMPHENICOL DERIVATIVE; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HELICOBACTER PYLORI; NONHUMAN;

ANTI-BACTERIAL AGENTS; CHLORAMPHENICOL; ENZYME INHIBITORS; HELICOBACTER PYLORI; METHIONINE; NITROGENOUS GROUP TRANSFERASES; PROPANOLAMINES;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

EID: 78449259554     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.09.045     Document Type: Article

References (22)

1. M. Ibba, C. Francklyn, S. Cusack, The Aminoacyl-tRNA Synthetases 2005 Eurekah.com/Landes Bioscience Georgetown, TX
2. J. Lapointe, L. Brakier-Gingras, Translation Mechanisms 2003 Landes Biosciences/Eurekah.com and Kluwer Academic/Plenum New York
3. J.L. Huot, J. Lapointe, R. Chênevert, M. Bailly, and D. Kern Glutaminyl-tRNA and Asparaginyl-tRNA Biosynthetic Pathways L. Mander, H.W. Liu, Comprehensive Natural Products II Chemistry and Biology Vol. 5 2010 Elsevier Oxford 383 431
4. L. Feng, D. Tumbula-Hansen, B. Min, S. Namgoog, J.C. Salazar, O. Orellana, and D. Söll Transfer RNA-dependant Amidotransferases: Key Enzymes for Asn-tRNA and Gln-tRNA Synthesis in Nature M. Ibba, C. Francklyn, S. Cusack, The Aminoacyl-tRNA Synthetases 2005 Landes Biosciences Georgetown, TX 314 319
5. K. Sheppard, R.L. Sherrer, and D. Söll J. Mol. Biol. 377 2008 845
6. E. Schmitt, M. Panvert, S. Blanquet, and Y. Mechulam Structure 13 2005 1421
7. A. Nakamura, M. Yao, S. Chimnaronk, N. Sakai, and I. Tanaka Science 312 2006 1954
8. H. Oshikane, K. Sheppard, S. Fukai, Y. Nakamura, R. Ishitani, T. Numata, R.L. Sherrer, L. Feng, E. Schmitt, M. Panvert, S. Blanquet, Y. Mechulam, D. Söll, and O. Nureki Science 312 2006 1950
9. J. Wu, W. Bu, K. Sheppard, M. Kitabatake, S.-T. Kwon, D. Söll, and J.L. Smith J. Mol. Biol. 391 2009 703
10. A.W. Curnow, K.-W. Hong, R. Yuan, S.-I. Kim, O. Martins, W. Winkler, T.M. Henkin, and D. Söll Proc. Natl. Acad. Sci. U.S.A. 94 1997 11819
11. S.F. Ataide, and M. Ibba ACS Chem. Biol. 1 2006 285
12. K.Y. Horiuchi, M.R. Harpel, L. Shen, Y. Luo, K.C. Rogers, and R.A. Copeland Biochemistry 40 2001 6450
13. C.P. Decicco, D.J. Nelson, Y. Luo, L. Shen, K.Y. Horiuchi, K.M. Amsler, L.A. Foster, S.M. Spitz, J.J. Merrill, C.F. Sizemore, K.C. Rogers, R.A. Copeland, and M.R. Harpel Bioorg. Med. Chem. Lett. 11 2001 2561
14. J.L. Huot, C. Balg, D. Jahn, J. Moser, A. Émond, S.P. Blais, R. Chênevert, and J. Lapointe Biochemistry 46 2007 13190
15. C. Balg, J.L. Huot, J. Lapointe, and R. Chênevert J. Am. Chem. Soc. 130 2008 3264
16. F. Schlünzen, R. Zarivach, J. Harms, A. Bashan, A. Tocilj, R. Albrecht, A. Yonath, and F. Franceschi Nature 413 2001 814
17. G.W. Moersch, and D.P. Hylander J. Am. Chem. Soc. 76 1954 1703
18. F. Marín-Martínez, and J. Sánchez-Meca Educ. Psychol. Meas. 70 2010 56
19. D. Drainas, P. Mamos, and C. Coutsogeorgopoulos J. Med. Chem. 36 1993 3542
20. R. Vince, R.G. Almquist, C.L. Ritter, and S. Daluge Antimicrob. Agents Chemother. 8 1975 439
21. M. Michelinaki, P. Mamos, C. Coutsogeorgopoulos, and D.L. Kalpaxis Mol. Pharmacol. 51 1997 139
22. J. Hiratake Chem. Rec. 5 2005 209