Mechanism of a GatCAB amidotransferase: Aspartyl-tRNA synthetase increases its affinity for Asp-tRNAAsn and novel aminoacyl-tRNA analogues are competitive inhibitors

Biochemistry

Volumn 46, Issue 45, 2007, Pages 13190-13198

  Huot, Jonathan L ^a   Balg, Christian ^a   Jahn, Dieter ^b   Moser, Jürgen ^b   Émond, Audrey ^a   Blais, Sébastien P ^a   Chênevert, Robert ^a   Lapointe, Jacques ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARCHAEA LACKING; COMPETITIVE INHIBITORS; GATCAB AMIDOTRANSFERASE; PHYSIOLOGICAL CONCENTRATION;

BACTERIA; CONCENTRATION (PROCESS); PHOSPHORYLATION; RNA; SYNTHESIS (CHEMICAL);

ENZYME ACTIVITY;

AMINOACYL TRANSFER RNA; ASPARTATE TRANSFER RNA LIGASE; ASPARTYCIN; ENZYME INHIBITOR; GLUTAMATE TRANSFER RNA LIGASE; GLUTAMINE TRANSFER RNA LIGASE; GLUTAMYCIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; AMIDATION; ARCHAEBACTERIUM; ARTICLE; BACTERIUM; CONTROLLED STUDY; ENZYME BINDING; ENZYME INACTIVATION; HELICOBACTER PYLORI; MOLECULAR DYNAMICS; NONHUMAN; PHOSPHORYLATION; PHYSIOLOGY; PRIORITY JOURNAL;

ADENOSINE; AMINOACYLTRANSFERASES; AMINOGLYCOSIDES; ASPARTATE-TRNA LIGASE; ASPARTIC ACID; HELICOBACTER PYLORI; NITROGENOUS GROUP TRANSFERASES;

EUKARYOTA; HELICOBACTER PYLORI;

EID: 36048943978     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700602n     Document Type: Article

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