Expanding the envelope of structure-based drug design using chemical libraries: Application to small-molecule inhibitors of thrombin

Medicinal Chemistry Research

Volumn 8, Issue 4-5, 1998, Pages 244-260

  Illig, Carl ^a   Eisennagel, Stephen ^a   Bone, Roger ^a   Radzicka, Anna ^a   Murphy, Larry ^a   Randle, Troy ^a   Spurlino, John ^a   Jaeger, Edward ^a   Salemme, F Raymond ^a   Soll, Richard M ^a  

^a JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SERINE PROTEINASE INHIBITOR; SULFONIC ACID DERIVATIVE; THROMBIN INHIBITOR;

ARTICLE; CALCULATION; CRYSTALLOGRAPHY; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 7844232027     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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