Study of the therapeutic benefit of cationic copolymer administration to vascular endothelium under mechanical stress

Biomaterials

Volumn 32, Issue 1, 2011, Pages 288-294

  Giantsos Adams, Kristina ^a   Lopez Quintero, Veronica ^b   Kopeckova, Pavla ^a   Kopecek, Jindrich ^a   Tarbell, John M ^b   Dull, Randal ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Acute respiratory distress syndrome; Endothelium; Mechanotransduction; Nitric oxide; Vascular tone and reactivity

Indexed keywords

ACUTE RESPIRATORY DISTRESS SYNDROME; BARRIER FUNCTIONS; CAPILLARY FILTRATION; CATIONIC COPOLYMER; CLINICAL PROBLEMS; CRITICAL CARE MEDICINE; ENDOTHELIUM; INTENSIVE CARE; MECHANICAL STRESS; MECHANICAL VENTILATION; MECHANOTRANSDUCTION; MOUSE LUNG; NOVEL STRATEGIES; PULMONARY EDEMA; THERAPEUTIC BENEFITS; THERAPEUTIC COMPOUNDS; TREATMENT MODALITY; VASCULAR ENDOTHELIUM; VASCULAR PERMEABILITY; VASCULAR TONE AND REACTIVITY;

COPOLYMERIZATION; COPOLYMERS; HYDRAULICS; HYDROSTATIC PRESSURE; INTENSIVE CARE UNITS; MEDICINE; NITRIC OXIDE; ORGANIC POLYMERS; PHYSIOLOGICAL MODELS; PLASTIC PRODUCTS; RESPIRATORY MECHANICS; STRESSES; VENTILATION;

MECHANICAL PERMEABILITY;

COPOLYMER; METHACRYLAMIDOPROPYLTRIMETHYLAMMONIUM CHLORIDE; METHACRYLIC ACID DERIVATIVE; N 2 HYDROXYPROPYL METHACRYLAMIDE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CATTLE; CONDUCTANCE; CONTROLLED STUDY; EX VIVO STUDY; INTENSIVE CARE; LUNG BLOOD VESSEL; LUNG EDEMA; MECHANOTRANSDUCTION; MICROVASCULATURE; MONOLAYER CULTURE; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; RESPIRATORY DISTRESS SYNDROME; SHEAR STRESS; SYNTHESIS; VASCULAR ENDOTHELIUM;

ANIMALS; CAPILLARIES; CATIONS; CATTLE; ENDOTHELIUM, VASCULAR; HYDROSTATIC PRESSURE; LUNG; NITRATES; NITRIC OXIDE; PERFUSION; POLYMERS; PRESSURE; RATS; STRESS, MECHANICAL; WATER;

EID: 78349309963     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.092     Document Type: Article

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