Self-assembled micellar aggregates based monomethoxyl poly(ethylene glycol)-b-poly(ε-caprolactone)-b-poly(aminoethyl methacrylate) triblock copolymers as efficient gene delivery vectors

Journal of Materials Science: Materials in Medicine

Volumn 21, Issue 10, 2010, Pages 2817-2825

  Ma, Ming ^a   Li, Feng ^a   Liu, Xiu Hong ^a   Yuan, Zhe Fan ^a   Chen, Fu Jie ^a   Zhuo, Ren Xi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHILIC TRIBLOCK COPOLYMERS; BINDING CAPABILITY; CAPROLACTONE; DIBLOCK COPOLYMER; GENE DELIVERY VECTORS; GENE VECTORS; LOCAL CHARGE; MICELLAR AGGREGATES; SELF-ASSEMBLED; STERIC HINDRANCE EFFECTS; SYNERGISTIC EFFECT; TRANSFECTION EFFICIENCY; TRIBLOCK COPOLYMERS;

BLOCK COPOLYMERS; BODY FLUIDS; CHARGED PARTICLES; COPOLYMERIZATION; ETHYLENE; ETHYLENE GLYCOL; GENE THERAPY; GENE TRANSFER; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE OXIDES;

POLYETHYLENE GLYCOLS;

BOVINE SERUM ALBUMIN; COPOLYMER; METHACRYLIC ACID DERIVATIVE; MONOMETHOXYL POLY(ETHYLENE GLYCOL); N TERT BUTOXYCARBONYLAMINOETHYLMETHACRYLATE; PLASMID DNA; POLY(AMINOETHYL METHACRYLATE); POLYCAPROLACTONE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CELL STRAIN COS7; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; GENE VECTOR; GENETIC TRANSFECTION; HYDROPHOBICITY; IN VITRO GENE TRANSFER; MACROMOLECULE; MICELLE; MOLECULAR INTERACTION; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PRIORITY JOURNAL; STEREOSPECIFICITY; SURFACE CHARGE; SYNTHESIS; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CERCOPITHECUS AETHIOPS; COS CELLS; DRUG CARRIERS; ETHYLAMINES; ETHYLENE GLYCOLS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MAGNETIC RESONANCE SPECTROSCOPY; MATERIALS TESTING; METHACRYLATES; MICELLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; TRANSFECTION;

EID: 78349306832     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-010-4140-3     Document Type: Article

References (31)

1. RC Mulligan 1993 The basic science of gene therapy Science 260 926 932 1:CAS:528:DyaK3sXktVSisbg%3D 10.1126/science.8493530 1993Sci...260..926M 8493530
2. D Luo WM Saltzman 2000 Synthetic DNA delivery systems Nat Biotechnol 18 33 37 1:CAS:528:DC%2BD3cXjs12jsQ%3D%3D 10.1038/71889 10625387 (Pubitemid 30041168)
3. M Morille C Passirani A Vonarbourg A Clavreul JP Benoit 2008 Progress in developing cationic vectors for non-viral systemic gene therapy against cancer Biomaterials 29 3477 3496 1:CAS:528:DC%2BD1cXntFGmsbg%3D 10.1016/j.biomaterials. 2008.04.036 18499247
4. S Lehrman 1999 Virus treatment questioned after gene therapy death Nature 401 517 518 1:CAS:528:DyaK1MXmvFCns7k%3D 10.1038/43977 1999Natur.401..517L 10524611
5. MA Mintzer EE Simanek 2009 Nonviral vectors for gene delivery Chem Rev 109 259 302 1:CAS:528:DC%2BD1cXhsVOjsL3L 10.1021/cr800409e 19053809
6. O Boussif F Lezoualc'h MA Zanta MD Mergny D Scherman B Demeneix JP Behr 1995 A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine Proc Natl Acad Sci USA 92 7297 7301 1:CAS:528:DyaK2MXntlKmt7s%3D 10.1073/pnas.92.16.7297 1995PNAS...92.7297B 7638184
7. E Wagner M Cotten R Foisner ML Birnstiel 1991 Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells Proc Natl Acad Sci USA 88 4255 4259 1:CAS:528: DyaK3MXkt1elsrg%3D 10.1073/pnas.88.10.4255 1991PNAS...88.4255W 2034670
8. JY Cherng VP Wetering H Talsma DJ Crommelin WE Hennink 1996 Effect of size and serum proteins on transfection efficiency of poly((2-dimethylamino) ethyl methacrylate) plasmid nanoparticles Pharm Res 13 1038 1042 1:CAS:528:DyaK28Xks1Sqsr4%3D 10.1023/A:1016054623543 8842041 (Pubitemid 26259003)
9. T Sato T Ishii Y Okahata 2001 In vitro gene delivery mediated by chitosan. Effect of pH, serum and molecular mass of chitosan on the transfection efficiency Biomaterials 22 2075 2080 1:CAS:528:DC%2BD3MXlt1Kmt7s%3D 10.1016/S0142-9612(00)00385-9 11432586 (Pubitemid 32738750)
10. J Haensler FC Szoka Jr 1993 Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjug Chem 4 372 379 1:CAS:528:DyaK3sXlslCqt7w%3D 10.1021/bc00023a012 8274523
11. SJ Hwang NC Bellocq ME Davis 2001 Effects of structure of β-cyclodextrin-containing polymers on gene delivery Bioconjug Chem 12 280 290 1:CAS:528:DC%2BD3MXhtFGmu78%3D 10.1021/bc0001084 11312690 (Pubitemid 32235481)
12. ED Hugger BL Novak PS Burton KL Audus RT Borchardt 2002 A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit p-glycoprotein activity in vitro J Pharm Sci 91 1991 2002 1:CAS:528:DC%2BD38XmsVSgs7Y%3D 10.1002/jps.10176 12210046 (Pubitemid 36254935)
13. SJ Hwang ME Davis 2001 Cationic polymers for gene delivery: designs for overcoming barriers to systemic administration Curr Opin Mol Ther 3 183 191 1:CAS:528:DC%2BD3MXjtlKitb0%3D 11338932
14. SV Vinogradov TK Bronich AV Kabanov 1998 Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides Bioconjug Chem 9 805 812 1:CAS:528:DyaK1cXmtlKgsr8%3D 10.1021/bc980048q 9815175 (Pubitemid 28542249)
15. HK Nguyen P Lemieux SV Vinogradov CL Gebhart N Guerin G Paradis TK Bronich VY Alakhov AV Kabanov 2000 Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents Gene Ther 7 126 138 1:CAS:528:DC%2BD3cXhtVSgtbs%3D 10.1038/sj.gt.3301052 10673718
16. B Ochietti P Lemieux AV Kabanov S Vinogradov Y St-Pierre V Alakhov 2002 Inducing neutrophil recruitment in the liver of ICAM-1-deficient mice using polyethyleimine grafted with Pluronic P123 as an organ-specific carrier for transgenic ICAM-1 Gene Ther 9 939 945 1:CAS:528:DC%2BD38Xksl2mtrg%3D 10.1038/sj.gt.3301716 12085242 (Pubitemid 34812284)
17. T Merdan K Kunath H Petersen U Bakowsky KH Voigt J Kopecek T Kissel 2005 PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice Bioconjug Chem 16 785 792 1:CAS:528:DC%2BD2MXltVCitbc%3D 10.1021/bc049743q 16029019 (Pubitemid 41026164)
18. S Mishra P Webster ME Davis 2004 PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles Eur J Cell Biol 83 97 111 1:CAS:528:DC%2BD2cXlvFOltb0%3D 10.1078/0171-9335-00363 15202568 (Pubitemid 38765217)
19. C Alvarez-Lorenzo R Barreiro-Iglesias A Concheiro L Iourtchenko V Alakhov L Bromberg M Temchenko S Deshmukh TA Hatton 2005 Biophysical characterization of complexation of DNA with block copolymers of poly(2-dimethylaminoethyl) methacrylate, poly(ethylene oxide), and poly(propylene oxide) Langmuir 21 5142 5148 1:CAS:528:DC%2BD2MXjt1Sku7g%3D 10.1021/la050170v 15896062 (Pubitemid 40795338)
20. CL Gebhart S Sriadibhatla S Vinogradov P Lemieux V Alakhov AV Kabanov 2002 Design and formulation of polyplexes based on pluronic-polyethyleneimine conjugates for gene transfer Bioconjug Chem 13 937 944 1:CAS:528: DC%2BD38Xmt1OqtLo%3D 10.1021/bc025504w 12236774
21. D Wang AS Narang M Kotb AO Gaber DD Miller SW Kim RI Mahato 2002 Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery Biomacromolecules 3 1197 1207 1:CAS:528:DC%2BD38XmslGns74%3D 10.1021/bm025563c 12425656 (Pubitemid 35423019)
22. EV Batrakova DW Miller S Li VY Alakhov AV Kabanov WF Elmquist 2001 Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies J Pharmacol Exp Ther 296 551 557 1:CAS:528:DC%2BD3MXoslejuw%3D%3D 11160643
23. WY Seow YY Yang 2009 A class of cationic triblock amphiphilic oligopeptides as efficient gene delivery vectors Adv Mater 21 86 90 1:CAS:528:DC%2BD1MXhtlCht7c%3D 10.1002/adma.200800928
24. DM Shendage R Frohlich G Haufe 2004 Highly efficient stereoconservative amidation and deamidation of alpha-amino acids Org Lett 6 3675 3678 1:CAS:528:DC%2BD2cXnvVKqtr4%3D 10.1021/ol048771l 15469321 (Pubitemid 39421920)
25. SH Hsu CM Tang CC Lin 2004 Biocompatibility of poly(epsilon-caprolactone) /poly(ethylene glycol) diblock copolymers with nanophase separation Biomaterials 25 5593 5601 1:CAS:528:DC%2BD2cXktFKku7s%3D 10.1016/j.biomaterials.2004.01.061 15159075 (Pubitemid 38680487)
26. L Yu H Zhang SX Cheng RX Zhuo H Li 2006 Study on the drug release property of cholesteryl end-functionalized poly(ε-caprolactone) microspheres J Biomed Mater Res B Appl Biomater 77B 39 46 1:CAS:528: DC%2BD28XjsFChur0%3D 10.1002/jbm.b.30395
27. H Wei XZ Zhang C Cheng SX Cheng RX Zhuo 2007 Self-assembled, thermosensitive micelles of a star block copolymer based on PMMA and PNIPAAm for controlled drug delivery Biomaterials 28 99 107 1:CAS:528:DC%2BD28XhtVWku7bF 10.1016/j.biomaterials.2006.08.030 16959312 (Pubitemid 44427903)
28. WL Zhang JL He Z Liu PH Ni XL Zhu 2010 Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: synthesis, self-assembly, and application J Polym Sci A Polym Chem 48 1079 1091 1:CAS:528:DC%2BC3cXht1yhsLY%3D 10.1002/pola.23863 2010JPoSA..48.1079Z
29. MR Capecchi 1980 High efficiency transformation by direct microinjection of DNA into cultured mammalian cells Cell 22 479 488 1:CAS:528: DyaL3MXmtFSlsQ%3D%3D 10.1016/0092-8674(80)90358-X 6256082
30. H Pollard JS Remy G Loussouarn S Demolombe JP Behr D Escande 1998 Polyethylenimine but not the cationic lipids promotes transgene delivery to the nucleus in mammalian cells J Biol Chem 273 7507 7511 1:CAS:528: DyaK1cXit1elsrw%3D 10.1074/jbc.273.13.7507 9516451 (Pubitemid 28152775)
31. ME Dowty P Williams G Zhang JE Hangstrom JA Wolff 1995 Plasmid DNA entry into post-mitotic nuclei of primary rat myotubes Proc Natl Acad Sci USA 92 4572 4576 1:CAS:528:DyaK2MXls1aksbY%3D 10.1073/pnas.92.10.4572 1995PNAS...92.4572D 7753845