Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats

International Journal of Pharmaceutics

Volumn 402, Issue 1-2, 2010, Pages 64-71

  Kutscher, Hilliard L ^a   Chao, Piyun ^a   Deshmukh, Manjeet ^a,b   Sundara Rajan, Sujata ^a   Singh, Yashveer ^a   Hu, Peidi ^a   Joseph, Laurie B ^a,b   Stein, Stanley ^a   Laskin, Debra L ^a,b   Sinko, Patrick J ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b Environmental and Occupational Health Sciences Institute   (United States)

Author keywords

Passive pulmonary targeting; PEGylation; Poly(ethylene glycol); Rigid non biodegradable microparticle

Indexed keywords

AMINE; CARBOXYL GROUP; MACROGOL; POLYSTYRENE; SULFATE;

ARTICLE; DRUG DISTRIBUTION; DRUG RETENTION; DRUG TARGETING; HYDROPHOBICITY; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROFLUOROMETRY; SURFACE PROPERTY; ZETA POTENTIAL;

ANIMALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LUNG; MALE; MICROSPHERES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYSTYRENES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, FLUORESCENCE; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 78349303955     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.09.020     Document Type: Article

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