-
1
-
-
67650236579
-
Abnormal angiogenesis in diabetic nephropathy
-
Nakagawa T, Kosugi T, Haneda M, et al. Abnormal angiogenesis in diabetic nephropathy. Diabetes 2009 58 1471-1478
-
(2009)
Diabetes
, vol.58
, pp. 1471-1478
-
-
Nakagawa, T.1
Kosugi, T.2
Haneda, M.3
-
2
-
-
33846669530
-
Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss
-
Baelde HJ, Eikmans M, Lappin DW, et al. Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss. Kidney Int 2007 71 637-645
-
(2007)
Kidney Int
, vol.71
, pp. 637-645
-
-
Baelde, H.J.1
Eikmans, M.2
Lappin, D.W.3
-
3
-
-
34250374471
-
Role of the VEGF a signaling pathway in the glomerulus: Evidence for crosstalk between components of the glomerular filtration barrier
-
Eremina V, Baelde HJ, Quaggin SE. Role of the VEGF a signaling pathway in the glomerulus: evidence for crosstalk between components of the glomerular filtration barrier. Nephron Physiol 2007 106 32-37
-
(2007)
Nephron Physiol
, vol.106
, pp. 32-37
-
-
Eremina, V.1
Baelde, H.J.2
Quaggin, S.E.3
-
4
-
-
58149343883
-
Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice
-
Ku CH, White KE, Dei CA, et al. Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice. Diabetes 2008 57 2824-2833
-
(2008)
Diabetes
, vol.57
, pp. 2824-2833
-
-
Ku, C.H.1
White, K.E.2
Dei, C.A.3
-
5
-
-
34447625374
-
Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: An explanation for the paradoxical effects of VEGF in renal disease
-
Nakagawa T. Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease. Am J Physiol Renal Physiol 2007 292 F1665-F1672
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Nakagawa, T.1
-
6
-
-
0034007216
-
Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes
-
Neugebauer S, Baba T, Watanabe T. Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes. Diabetes 2000 49 500-503
-
(2000)
Diabetes
, vol.49
, pp. 500-503
-
-
Neugebauer, S.1
Baba, T.2
Watanabe, T.3
-
7
-
-
0033917346
-
Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism
-
Zanchi A, Moczulski DK, Hanna LS, et al. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism. Kidney Int 2000 57 405-413
-
(2000)
Kidney Int
, vol.57
, pp. 405-413
-
-
Zanchi, A.1
Moczulski, D.K.2
Hanna, L.S.3
-
8
-
-
33846701668
-
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy
-
Nakagawa T, Sato W, Glushakova O, et al. Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol 2007 18 539-550
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 539-550
-
-
Nakagawa, T.1
Sato, W.2
Glushakova, O.3
-
9
-
-
33749236623
-
Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice
-
Zhao HJ, Wang S, Cheng H, et al. Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. J Am Soc Nephrol 2006 17 2664-2669
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2664-2669
-
-
Zhao, H.J.1
Wang, S.2
Cheng, H.3
-
10
-
-
33645456312
-
Uncoupling of vascular endothelial growth factor with nitric oxide as a mechanism for diabetic vasculopathy
-
Nakagawa T, Sato W, Sautin YY, et al. Uncoupling of vascular endothelial growth factor with nitric oxide as a mechanism for diabetic vasculopathy. J Am Soc Nephrol 2006 17 736-745
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 736-745
-
-
Nakagawa, T.1
Sato, W.2
Sautin, Y.Y.3
-
11
-
-
34547628176
-
Podocyte-specific expression of angiopoetin-2 causes proteinuria and apoptosis of glomerular endothelia
-
Davis B, Dei CA, Long DA, et al. Podocyte-specific expression of angiopoetin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol 2007 18 2320-2329
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2320-2329
-
-
Davis, B.1
Dei, C.A.2
Long, D.A.3
-
12
-
-
35948934636
-
Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis
-
Isermann B, Vinnikov IA, Madhusudhan T, et al. Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. Nat Med 2007 13 1349-1358
-
(2007)
Nat Med
, vol.13
, pp. 1349-1358
-
-
Isermann, B.1
Vinnikov, I.A.2
Madhusudhan, T.3
-
13
-
-
42049123672
-
Activated protein C and diabetic nephropathy
-
Gilbert RE, Marsden PA. Activated protein C and diabetic nephropathy. N Engl J Med 2008 358 1628-1630
-
(2008)
N Engl J Med
, vol.358
, pp. 1628-1630
-
-
Gilbert, R.E.1
Marsden, P.A.2
-
14
-
-
0034892611
-
Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis
-
Isermann B, Hendrickson SB, Zogg M, et al. Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. J Clin Invest 2001 108 537-546
-
(2001)
J Clin Invest
, vol.108
, pp. 537-546
-
-
Isermann, B.1
Hendrickson, S.B.2
Zogg, M.3
-
16
-
-
0032250114
-
Circulating thrombomodulin and hematological alterations in type 2 diabetic patients with retinopathy
-
Fujiwara Y, Tagami S, Kawakami Y. Circulating thrombomodulin and hematological alterations in type 2 diabetic patients with retinopathy. J Atheroscler Thromb 1998 5 21-28
-
(1998)
J Atheroscler Thromb
, vol.5
, pp. 21-28
-
-
Fujiwara, Y.1
Tagami, S.2
Kawakami, Y.3
-
17
-
-
0032794198
-
Influence of ramipril on the course of plasma thrombomodulin in patients with diabetes mellitus
-
Borcea V, Morcos M, Isermann B, et al. Influence of ramipril on the course of plasma thrombomodulin in patients with diabetes mellitus. Vasa 1999 28 172-180
-
(1999)
Vasa
, vol.28
, pp. 172-180
-
-
Borcea, V.1
Morcos, M.2
Isermann, B.3
-
18
-
-
36549001620
-
Inverse correlation between activated protein C generation and carotid atherosclerosis in Type 2 diabetic patients
-
Matsumoto K, Yano Y, Gabazza EC, et al. Inverse correlation between activated protein C generation and carotid atherosclerosis in Type 2 diabetic patients. Diabet Med 2007 24 1322-1328
-
(2007)
Diabet Med
, vol.24
, pp. 1322-1328
-
-
Matsumoto, K.1
Yano, Y.2
Gabazza, E.C.3
-
19
-
-
0037349926
-
The thrombomodulin-protein C system is essential for the maintenance of pregnancy
-
Isermann B, Sood R, Pawlinski R, et al. The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med 2003 9 331-337
-
(2003)
Nat Med
, vol.9
, pp. 331-337
-
-
Isermann, B.1
Sood, R.2
Pawlinski, R.3
-
20
-
-
0027103736
-
Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation
-
Glaser CB, Morser J, Clarke JH, et al. Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation. J Clin Invest 1992 90 2565-2573
-
(1992)
J Clin Invest
, vol.90
, pp. 2565-2573
-
-
Glaser, C.B.1
Morser, J.2
Clarke, J.H.3
-
21
-
-
67649502995
-
Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes
-
Ceriello A, Esposito K, Ihnat M, et al. Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes. J Thromb Haemost 2009 7 1228-1230
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1228-1230
-
-
Ceriello, A.1
Esposito, K.2
Ihnat, M.3
-
22
-
-
72849119793
-
Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1
-
Gupta A, Williams MD, Macias WL, et al. Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1. Curr Drug Targets 2009
-
(2009)
Curr Drug Targets
-
-
Gupta, A.1
Williams, M.D.2
MacIas, W.L.3
-
23
-
-
36249020418
-
Role reversal for the receptor PAR1 in sepsis-induced vascular damage
-
Kaneider NC, Leger AJ, Agarwal A, et al. Role reversal for the receptor PAR1 in sepsis-induced vascular damage. Nat Immunol 2007 8 1303-1312
-
(2007)
Nat Immunol
, vol.8
, pp. 1303-1312
-
-
Kaneider, N.C.1
Leger, A.J.2
Agarwal, A.3
-
24
-
-
3543148984
-
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: Role of advanced glycation end products
-
Lassila M, Seah KK, Allen TJ, et al. Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products. J Am Soc Nephrol 2004 15 2125-2138
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2125-2138
-
-
Lassila, M.1
Seah, K.K.2
Allen, T.J.3
-
25
-
-
38949210220
-
Effect of a multifactorial intervention on mortality in type 2 diabetes
-
Gaede P, Lund-Andersen H, Parving HH, et al. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med 2008 358 580-591
-
(2008)
N Engl J Med
, vol.358
, pp. 580-591
-
-
Gaede, P.1
Lund-Andersen, H.2
Parving, H.H.3
-
26
-
-
33750580307
-
Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes
-
Proctor G, Jiang T, Iwahashi M, et al. Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. Diabetes 2006 55 2502-2509
-
(2006)
Diabetes
, vol.55
, pp. 2502-2509
-
-
Proctor, G.1
Jiang, T.2
Iwahashi, M.3
-
27
-
-
33846113744
-
Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats
-
Komers R, Lindsley JN, Oyama TT, et al. Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. Clin Exp Pharmacol Physiol 2007 34 36-41
-
(2007)
Clin Exp Pharmacol Physiol
, vol.34
, pp. 36-41
-
-
Komers, R.1
Lindsley, J.N.2
Oyama, T.T.3
-
28
-
-
33847094658
-
Association of low-grade inflammation with nephropathy in type 2 diabetic patients: Role of elevated CRP-levels and 2 different gene-polymorphisms of proinflammatory cytokines
-
Abrahamian H, Endler G, Exner M, et al. Association of low-grade inflammation with nephropathy in type 2 diabetic patients: role of elevated CRP-levels and 2 different gene-polymorphisms of proinflammatory cytokines. Exp Clin Endocrinol Diabetes 2007 115 38-41
-
(2007)
Exp Clin Endocrinol Diabetes
, vol.115
, pp. 38-41
-
-
Abrahamian, H.1
Endler, G.2
Exner, M.3
-
29
-
-
33645454310
-
Leukocyte recruitment and vascular injury in diabetic nephropathy
-
Galkina E, Ley K. Leukocyte recruitment and vascular injury in diabetic nephropathy. J Am Soc Nephrol 2006 17 368-377
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 368-377
-
-
Galkina, E.1
Ley, K.2
-
30
-
-
26944480830
-
Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice
-
Chow FY, Nikolic-Paterson DJ, Ozols E, et al. Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice. J Am Soc Nephrol 2005 16 1711-1722
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1711-1722
-
-
Chow, F.Y.1
Nikolic-Paterson, D.J.2
Ozols, E.3
-
31
-
-
62149114830
-
Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice
-
Xiao X, Ma B, Dong B, et al. Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice. J Autoimmun 2009 32 85-93
-
(2009)
J Autoimmun
, vol.32
, pp. 85-93
-
-
Xiao, X.1
Ma, B.2
Dong, B.3
-
32
-
-
0942279565
-
Juxtaglomerular apparatus T-cell infiltration affects glomerular structure in Type 1 diabetic patients
-
Moriya R, Manivel JC, Mauer M. Juxtaglomerular apparatus T-cell infiltration affects glomerular structure in Type 1 diabetic patients. Diabetologia 2004 47 82-88
-
(2004)
Diabetologia
, vol.47
, pp. 82-88
-
-
Moriya, R.1
Manivel, J.C.2
Mauer, M.3
-
33
-
-
50249148344
-
The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy
-
Sato W, Kosugi T, Zhang L, et al. The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Lab Invest 2008 88 949-961
-
(2008)
Lab Invest
, vol.88
, pp. 949-961
-
-
Sato, W.1
Kosugi, T.2
Zhang, L.3
-
34
-
-
70349149467
-
Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes
-
Tarabra E, Giunti S, Barutta F, et al. Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes 2009 58 2109-2118
-
(2009)
Diabetes
, vol.58
, pp. 2109-2118
-
-
Tarabra, E.1
Giunti, S.2
Barutta, F.3
-
35
-
-
70350536554
-
Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy
-
Pezzolesi MG, Katavetin P, Kure M, et al. Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy. Diabetes 2009 58 2698-2702
-
(2009)
Diabetes
, vol.58
, pp. 2698-2702
-
-
Pezzolesi, M.G.1
Katavetin, P.2
Kure, M.3
-
36
-
-
62149122940
-
Impaired tubular uptake explains albuminuria in early diabetic nephropathy
-
Russo LM, Sandoval RM, Campos SB, et al. Impaired tubular uptake explains albuminuria in early diabetic nephropathy. J Am Soc Nephrol 2009 20 489-494
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 489-494
-
-
Russo, L.M.1
Sandoval, R.M.2
Campos, S.B.3
-
37
-
-
33847682663
-
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
-
Kato M, Zhang J, Wang M, et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A 2007 104 3432-3437
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3432-3437
-
-
Kato, M.1
Zhang, J.2
Wang, M.3
-
38
-
-
33747043113
-
Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN
-
Mahimainathan L, Das F, Venkatesan B, et al. Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN. Diabetes 2006 55 2115-2125
-
(2006)
Diabetes
, vol.55
, pp. 2115-2125
-
-
Mahimainathan, L.1
Das, F.2
Venkatesan, B.3
-
39
-
-
67349089523
-
MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice
-
Zhang Z, Peng H, Chen J, et al. MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice. FEBS Lett 2009 583 2009-2014
-
(2009)
FEBS Lett
, vol.583
, pp. 2009-2014
-
-
Zhang, Z.1
Peng, H.2
Chen, J.3
-
40
-
-
67650085171
-
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
-
Kato M, Putta S, Wang M, et al. TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat Cell Biol 2009 11 881-889
-
(2009)
Nat Cell Biol
, vol.11
, pp. 881-889
-
-
Kato, M.1
Putta, S.2
Wang, M.3
-
41
-
-
69849089270
-
Wnt/beta-catenin signalling promotes podocyte dysfunction and albuminuria
-
Dai C, Stolz DB, Kiss LP, et al. Wnt/beta-catenin signalling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 2009 20 1997-2008
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1997-2008
-
-
Dai, C.1
Stolz, D.B.2
Kiss, L.P.3
-
42
-
-
67650065522
-
Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: Involvement of Notch, Wnt, and HIF-1alpha
-
Lee SH, Kim MH, Han HJ. Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha. Am J Physiol Cell Physiol 2009 297 C207-C216
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Lee, S.H.1
Kim, M.H.2
Han, H.J.3
-
43
-
-
0034758712
-
Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy
-
Wang SN, Lapage J, Hirschberg R. Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J Am Soc Nephrol 2001 12 2392-2399
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 2392-2399
-
-
Wang, S.N.1
Lapage, J.2
Hirschberg, R.3
-
44
-
-
20444364531
-
Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy
-
Dolan V, Murphy M, Sadlier D, et al. Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy. Am J Kidney Dis 2005 45 1034-1039
-
(2005)
Am J Kidney Dis
, vol.45
, pp. 1034-1039
-
-
Dolan, V.1
Murphy, M.2
Sadlier, D.3
-
45
-
-
0037648482
-
Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy
-
Wang S, Chen Q, Simon TC, et al. Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy. Kidney Int 2003 63 2037-2049
-
(2003)
Kidney Int
, vol.63
, pp. 2037-2049
-
-
Wang, S.1
Chen, Q.2
Simon, T.C.3
-
46
-
-
39149086711
-
Co-regulation of Gremlin and Notch signalling in diabetic nephropathy
-
Walsh DW, Roxburgh SA, McGettigan P, et al. Co-regulation of Gremlin and Notch signalling in diabetic nephropathy. Biochim Biophys Acta 2008 1782 10-21
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 10-21
-
-
Walsh, D.W.1
Roxburgh, S.A.2
McGettigan, P.3
-
47
-
-
67650065522
-
Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: Involvement of Notch, Wnt, and HIF-1alpha
-
Lee SH, Kim MH, Han HJ. Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha. Am J Physiol Cell Physiol 2009 297 C207-C216
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Lee, S.H.1
Kim, M.H.2
Han, H.J.3
-
48
-
-
40449112321
-
The Notch pathway in podocytes plays a role in the development of glomerular disease
-
Niranjan T, Bielesz B, Gruenwald A, et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med 2008 14 290-298
-
(2008)
Nat Med
, vol.14
, pp. 290-298
-
-
Niranjan, T.1
Bielesz, B.2
Gruenwald, A.3
-
49
-
-
39149086711
-
Co-regulation of Gremlin and Notch signalling in diabetic nephropathy
-
Walsh DW, Roxburgh SA, McGettigan P, et al. Co-regulation of Gremlin and Notch signalling in diabetic nephropathy. Biochim Biophys Acta 2008 1782 10-21
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 10-21
-
-
Walsh, D.W.1
Roxburgh, S.A.2
McGettigan, P.3
|