메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages 251-260

Drug discovery in ovarian cancer

Author keywords

Angiogenesis; Chemotherapy; Clinical trials; Ovarian cancer; Recurrent cancer; Targeted therapy

Indexed keywords

AFLIBERCEPT; AMG 386; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BIBF 1120; CANCER VACCINE; CANFOSFAMIDE; CARBOPLATIN; CISPLATIN; CYTOTOXIC AGENT; DOXORUBICIN; EC 145; EVEROLIMUS; GDC 0449; IMC 112B; IMC 3G3; MONOCLONAL ANTIBODY; OLAPARIB; PACLITAXEL; PAZOPANIB; PLACEBO; PLATINUM AMMINE CYCLOHEXYLAMINE DICHLORIDE; PV 701; RAMUCIRUMAB; SATRAPLATIN; TOPOTECAN; TRABECTIDIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VOLOCIXIMAB; ENDOTHELIAL CELL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 78349249813     PISSN: 15748928     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489210791760472     Document Type: Article
Times cited : (6)

References (70)
  • 1
    • 63849310246 scopus 로고    scopus 로고
    • Crosstalk of and in tumour: Therapeutic implications
    • Li JL, Harris AL. Crosstalk of and in tumour: Therapeutic implications. Front Biosci 2009; 14: 3094-3110.
    • (2009) Front Biosci , vol.14 , pp. 3094-3110
    • Li, J.L.1    Harris, A.L.2
  • 3
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
    • Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study. J Clin Oncol 2007; 25(33): 5165-71.
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 4
    • 36849056497 scopus 로고    scopus 로고
    • Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
    • Erratum in: J Clin Oncol 2008; 26(10): 1773
    • Cannistra SA, Matulonis UA, Penson RT, Hambleton J, Dupont J, Mackey H, et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer. J Clin Oncol 2007; 25(33): 5180-6. Erratum in: J Clin Oncol 2008; 26(10): 1773.
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5180-5186
    • Cannistra, S.A.1    Matulonis, U.A.2    Penson, R.T.3    Hambleton, J.4    Dupont, J.5    Mackey, H.6
  • 5
    • 34447317037 scopus 로고    scopus 로고
    • Strategies for suppressing angiogenesis in gynecologic cancers
    • Ma WW, Jimeno A. Strategies for suppressing angiogenesis in gynecologic cancers. Drugs Today (Barc) 2007; 43(4): 259-73.
    • (2007) Drugs Today (Barc) , vol.43 , Issue.4 , pp. 259-273
    • Ma, W.W.1    Jimeno, A.2
  • 6
    • 0345060442 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model
    • Byrne AT, Ross L, Holash J, Nakanishi M, Hu L, Hofmann J, et al. Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model. Clin Cancer Res 2003; 9: 5721-28.
    • (2003) Clin Cancer Res , vol.9 , pp. 5721-5728
    • Byrne, A.T.1    Ross, L.2    Holash, J.3    Nakanishi, M.4    Hu, L.5    Hofmann, J.6
  • 8
    • 69549140332 scopus 로고    scopus 로고
    • Aflibercept (VEGF Trap) for advanced epithelial ovarian cancer (EOC) patients (pts) with symptomatic malignant ascites: Preliminary results of a pilot study
    • (May 20 suppl; abstr 14598). 2008 ASCO Annual Meeting
    • Colombo N, Mangili G, Mammoliti S, Kalling M, Tholander B, Sternas L, et al. Aflibercept (VEGF Trap) for advanced epithelial ovarian cancer (EOC) patients (pts) with symptomatic malignant ascites: Preliminary results of a pilot study. J Clin Oncol 2008; 26: (May 20 suppl; abstr 14598). 2008 ASCO Annual Meeting.
    • (2008) J Clin Oncol , vol.26
    • Colombo, N.1    Mangili, G.2    Mammoliti, S.3    Kalling, M.4    Tholander, B.5    Sternas, L.6
  • 9
    • 36849005801 scopus 로고    scopus 로고
    • VEGF-Trap for patients with recurrent platinum-resistant epithelial ovarian cancer (EOC): Preliminary results of a randomized, multicenter phase II study
    • Tew WP, Colombo I, Ray-Coquard A, del Campo J, Scambia G, Springgs D. VEGF-Trap for patients with recurrent platinum-resistant epithelial ovarian cancer (EOC): Preliminary results of a randomized, multicenter phase II study. J Clin Oncol 2007; 25(18S): 5508.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 5508
    • Tew, W.P.1    Colombo, I.2    Ray-Coquard, A.3    del Campo, J.4    Scambia, G.5    Springgs, D.6
  • 11
    • 33751418762 scopus 로고    scopus 로고
    • A phase I dose-escalation study of weekly IMC-1121B, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR2) IgG1 monoclonal antibody (Mab), in patients (pts) with advanced cancer
    • June 20
    • Camidge DR, Eckhardt SG, Diab S, Gore L, Chow L, O'Bryant C, et al. A phase I dose-escalation study of weekly IMC-1121B, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR2) IgG1 monoclonal antibody (Mab), in patients (pts) with advanced cancer. J Clin Oncol 2006 ASCO Annual Meeting Proceedings Part I. vol. 24, no. 18S (June 20 Suppl), 2006: 3032.
    • (2006) J Clin Oncol 2006 ASCO Annual Meeting Proceedings Part I , vol.24 , Issue.SUPPL. , pp. 3032
    • Camidge, D.R.1    Eckhardt, S.G.2    Diab, S.3    Gore, L.4    Chow, L.5    O'Bryant, C.6
  • 12
    • 78649359702 scopus 로고    scopus 로고
    • (Accessed on: June 18, 2010)
    • http://clinicaltrials.gov/ct2/show/NCT00479817 (Accessed on: June 18, 2010).
  • 13
    • 0038745370 scopus 로고    scopus 로고
    • Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
    • Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 2003; 63(12): 3403-12.
    • (2003) Cancer Res , vol.63 , Issue.12 , pp. 3403-3412
    • Zhang, L.1    Yang, N.2    Park, J.W.3    Katsaros, D.4    Fracchioli, S.5    Cao, G.6
  • 14
    • 1842582434 scopus 로고    scopus 로고
    • Expression of the angopoietin-1, angopoietin-2, Tie2, and vascular endothelial growth factor gene in epithelial ovarian cancer
    • Hata K, Nakayama K, Fujiwaki R, Katabuchi H, Okamura H, Miyazaki K. Expression of the angopoietin-1, angopoietin-2, Tie2, and vascular endothelial growth factor gene in epithelial ovarian cancer. Gynecol Oncol 2004; 93(1): 215-22.
    • (2004) Gynecol Oncol , vol.93 , Issue.1 , pp. 215-222
    • Hata, K.1    Nakayama, K.2    Fujiwaki, R.3    Katabuchi, H.4    Okamura, H.5    Miyazaki, K.6
  • 16
    • 70249114453 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors
    • Herbst R, Hong D, Chap L, Kurzrock R, Jackson E, Silverman J, et al. Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. J Clin Oncol 2009; 27(21): 3557-65.
    • (2009) J Clin Oncol , vol.27 , Issue.21 , pp. 3557-3565
    • Herbst, R.1    Hong, D.2    Chap, L.3    Kurzrock, R.4    Jackson, E.5    Silverman, J.6
  • 17
    • 0033763567 scopus 로고    scopus 로고
    • Involvement of platelet-derived growth factor in disease: Development of specific antagonists
    • Ostman A, Heldin CH. Involvement of platelet-derived growth factor in disease: Development of specific antagonists. Adv Cancer Res 2001; 80: 1-38.
    • (2001) Adv Cancer Res , vol.80 , pp. 1-38
    • Ostman, A.1    Heldin, C.H.2
  • 19
    • 0027365546 scopus 로고
    • Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms
    • Henriksen R, Funa K, Wilander E, Backstrom T, Ridderheim M, Oberg K. Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res 1993; 53: 4550-4.
    • (1993) Cancer Res , vol.53 , pp. 4550-4554
    • Henriksen, R.1    Funa, K.2    Wilander, E.3    Backstrom, T.4    Ridderheim, M.5    Oberg, K.6
  • 20
    • 84902022127 scopus 로고    scopus 로고
    • Phase 1 study of IMC-3G3, an IgG1 monoclonal antibody targeting PDGFR in patients with advanced solid malignancies
    • Youssoufian, Amato RJ, Sweeney CJ, Chiorean EG, Fox F, Katz T, et al. Phase 1 study of IMC-3G3, an IgG1 monoclonal antibody targeting PDGFR in patients with advanced solid malignancies. J Clin Oncol (Meeting Abstracts) 2008 26: 14617.
    • (2008) J Clin Oncol (Meeting Abstracts) , vol.26 , pp. 14617
    • Youssoufian Amato, R.J.1    Sweeney, C.J.2    Chiorean, E.G.3    Fox, F.4    Katz, T.5
  • 23
    • 33749349945 scopus 로고    scopus 로고
    • Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent
    • Ramakrishnan V, Bhaskar V, Law DA, Wong MH, DuBridge RB, Breinberg D, et al. Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent. J Exp Ther Oncol 2006; 5(4): 273-86.
    • (2006) J Exp Ther Oncol , vol.5 , Issue.4 , pp. 273-286
    • Ramakrishnan, V.1    Bhaskar, V.2    Law, D.A.3    Wong, M.H.4    Dubridge, R.B.5    Breinberg, D.6
  • 24
    • 39049171151 scopus 로고    scopus 로고
    • A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo
    • Bhaskar V, Zhang D, Fox M, Seto P, Wong MH, Wales PE, et al. A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo. J Transl Med 2007; 5: 61.
    • (2007) J Transl Med , vol.5 , pp. 61
    • Bhaskar, V.1    Zhang, D.2    Fox, M.3    Seto, P.4    Wong, M.H.5    Wales, P.E.6
  • 26
    • 59449094255 scopus 로고    scopus 로고
    • Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: A phase I, pharmacokinetic, and biological correlative study
    • Ricart AD, Tolcher AW, Liu G, Holen K, Schwartz G, Albertini M, et al. Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: A phase I, pharmacokinetic, and biological correlative study. Clin Cancer Res 2008; 14(23): 7924-9.
    • (2008) Clin Cancer Res , vol.14 , Issue.23 , pp. 7924-7929
    • Ricart, A.D.1    Tolcher, A.W.2    Liu, G.3    Holen, K.4    Schwartz, G.5    Albertini, M.6
  • 27
    • 41149151093 scopus 로고    scopus 로고
    • Final results from phase II study of volociximab, an 5 1 anti-integrin antibody, In refractory or relapsed metastatic clear cell renal cell carcinoma (mCCRCC)
    • June 20
    • Yazji S, Bukowski R, Kondagunta V, Figlin R. Final results from phase II study of volociximab, an 5 1 anti-integrin antibody, In refractory or relapsed metastatic clear cell renal cell carcinoma (mCCRCC). J Clin Oncol 2007 ASCO Annual Meeting Proceedings Part I. vol. 25, no. 18S (June 20 Suppl), 2007: 5094.
    • (2007) J Clin Oncol 2007 ASCO Annual Meeting Proceedings Part I , vol.25 , Issue.SUPPL , pp. 5094
    • Yazji, S.1    Bukowski, R.2    Kondagunta, V.3    Figlin, R.4
  • 28
    • 78649356052 scopus 로고    scopus 로고
    • Phase II study comparing volociximab (an antiangiogenic antibody) and pegylated liposomal doxorubicin (PLD) with PLD alone in recurrent ovarian or primary peritoneal cancer
    • ASCO Annual Meeting Proceedings (Post-meeting Edition) 27(15S): 5560
    • Vergote IB, Colombo N, Kutarska E, Del Campo J, Pippitt C, Casado A, et al. Phase II study comparing volociximab (an antiangiogenic antibody) and pegylated liposomal doxorubicin (PLD) with PLD alone in recurrent ovarian or primary peritoneal cancer. J Clin Oncol 2009; ASCO Annual Meeting Proceedings (Post-meeting Edition) 27(15S): 5560.
    • (2009) J Clin Oncol
    • Vergote, I.B.1    Colombo, N.2    Kutarska, E.3    Del Campo, J.4    Pippitt, C.5    Casado, A.6
  • 30
    • 49649123154 scopus 로고    scopus 로고
    • BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockage and good antitumor efficacy
    • Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, et al. BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockage and good antitumor efficacy. Cancer Res 2008; 68(12): 4774-82.
    • (2008) Cancer Res , vol.68 , Issue.12 , pp. 4774-4782
    • Hilberg, F.1    Roth, G.J.2    Krssak, M.3    Kautschitsch, S.4    Sommergruber, W.5    Tontsch-Grunt, U.6
  • 31
    • 77951895481 scopus 로고    scopus 로고
    • A phase I open-label dose-escalation study of oral BIBF 1120 combined with standard paclitaxel and carboplatin in patients with advanced gynecological malignancies
    • du Bois A, Huober J, Stopfer P, Pfisterer J, Wimberger P, Loibl S, et al. A phase I open-label dose-escalation study of oral BIBF 1120 combined with standard paclitaxel and carboplatin in patients with advanced gynecological malignancies. Ann Oncol 2010; 21(2): 370-5.
    • (2010) Ann Oncol , vol.21 , Issue.2 , pp. 370-375
    • du Bois, A.1    Huober, J.2    Stopfer, P.3    Pfisterer, J.4    Wimberger, P.5    Loibl, S.6
  • 33
    • 78649358264 scopus 로고    scopus 로고
    • (Accessed on: June 18, 2010)
    • http://clinicaltrials.gov/ct2/show/NCT00516373?term=PARP&rank =1 (Accessed on: June 18, 2010).
  • 34
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009; 361(2): 123-34.
    • (2009) N Engl J Med , vol.361 , Issue.2 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3    Tutt, A.4    Wu, P.5    Mergui-Roelvink, M.6
  • 35
    • 68149161777 scopus 로고    scopus 로고
    • Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer
    • abstr 5500
    • Audeh MW, Penson RT, Friedlander B, Powell B, Bell-McGuinn KM, Scott C, et al. Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. J Clin Oncol 2009; 27: 15s, (suppl; abstr 5500).
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Audeh, M.W.1    Penson, R.T.2    Friedlander, B.3    Powell, B.4    Bell-McGuinn, K.M.5    Scott, C.6
  • 37
    • 69949109923 scopus 로고    scopus 로고
    • mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary
    • Mabuchi S, Kawase C, Altomare DA, Morishige K, Sawada K, Hayashi M, et al. mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. Clin Cancer Res 2009; 15(17): 5404-13.
    • (2009) Clin Cancer Res , vol.15 , Issue.17 , pp. 5404-5413
    • Mabuchi, S.1    Kawase, C.2    Altomare, D.A.3    Morishige, K.4    Sawada, K.5    Hayashi, M.6
  • 38
    • 58749107489 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours
    • Campone M, Levy V, Bourbouloux E, Rigaud BD, Bootle D, Dutreix C, et al. Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours. Br J Cancer 2009; 100(2): 315-21.
    • (2009) Br J Cancer , vol.100 , Issue.2 , pp. 315-321
    • Campone, M.1    Levy, V.2    Bourbouloux, E.3    Rigaud, B.D.4    Bootle, D.5    Dutreix, C.6
  • 42
    • 34447131647 scopus 로고    scopus 로고
    • Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145
    • Leaman CP, Reddy JA, Wlahov IR, Westrick E, Parker N, Nicoson JS, et al. Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145. Int J Cancer 2007; 121:1585-92.
    • (2007) Int J Cancer , vol.121 , pp. 1585-1592
    • Leaman, C.P.1    Reddy, J.A.2    Wlahov, I.R.3    Westrick, E.4    Parker, N.5    Nicoson, J.S.6
  • 43
    • 34249321972 scopus 로고    scopus 로고
    • Preclinical evaluation of EC145, a Folate-Vinca alkaloid conjugate
    • Reddy JA, Dorton R, Westrick E, Dawson A, Smith T, Xu L, et al. Preclinical evaluation of EC145, a Folate-Vinca alkaloid conjugate. Cancer Res 2007; 67(9): 4434-42.
    • (2007) Cancer Res , vol.67 , Issue.9 , pp. 4434-4442
    • Reddy, J.A.1    Dorton, R.2    Westrick, E.3    Dawson, A.4    Smith, T.5    Xu, L.6
  • 44
    • 71449112911 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and exposure- toxicity relationship of a folate-Vinca alkaloid conjugate EC145 in cancer patients
    • Li J, Sausville EA, Klein PJ, Morgenstern D, Leamon CP, Messmann RA, et al. Clinical pharmacokinetics and exposure- toxicity relationship of a folate-Vinca alkaloid conjugate EC145 in cancer patients. J Clin Pharmacol 2009; 49(12): 1467-76.
    • (2009) J Clin Pharmacol , vol.49 , Issue.12 , pp. 1467-1476
    • Li, J.1    Sausville, E.A.2    Klein, P.J.3    Morgenstern, D.4    Leamon, C.P.5    Messmann, R.A.6
  • 46
    • 70349132675 scopus 로고    scopus 로고
    • ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines
    • Duan Z, Choy E, Harmon D, Yang C, Ryu K, Schwab J, et al. ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines. PLoS One 2009; 4(9): e6967.
    • (2009) PLoS One , vol.4 , Issue.9
    • Duan, Z.1    Choy, E.2    Harmon, D.3    Yang, C.4    Ryu, K.5    Schwab, J.6
  • 47
    • 71049192700 scopus 로고    scopus 로고
    • Yondelis Ovarian Cancer Group. Phase II randomized study of trabectedin given as two different every 3 weeks dose schedules (1.5 mg/m2 24 h or 1.3 mg/m2 3 h) to patients with relapsed, platinum-sensitive, advanced ovarian cancer
    • Del Campo JM, Roszak A, Bidzinski M, Ciuleanu TE, Hogberg T, Wojtukiewicz MZ, et al. Yondelis Ovarian Cancer Group. Phase II randomized study of trabectedin given as two different every 3 weeks dose schedules (1.5 mg/m2 24 h or 1.3 mg/m2 3 h) to patients with relapsed, platinum-sensitive, advanced ovarian cancer. Ann Oncol 2009; 20(11): 1794-802.
    • (2009) Ann Oncol , vol.20 , Issue.11 , pp. 1794-1802
    • Del Campo, J.M.1    Roszak, A.2    Bidzinski, M.3    Ciuleanu, T.E.4    Hogberg, T.5    Wojtukiewicz, M.Z.6
  • 50
    • 68749089764 scopus 로고    scopus 로고
    • Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer
    • Vergote I, Finkler N, del Campo J, Lohr A, Hunter J, Matei D, et al. Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer. Eur J Cancer 2009; 45(13): 2324-32.
    • (2009) Eur J Cancer , vol.45 , Issue.13 , pp. 2324-2332
    • Vergote, I.1    Finkler, N.2    del Campo, J.3    Lohr, A.4    Hunter, J.5    Matei, D.6
  • 51
    • 78649347857 scopus 로고    scopus 로고
    • Anticancer (IV) complexes for oral administration and a method of making the same
    • Sohn, Y.S., Lee, S.S., Lee, Y.A., Kim, K.M., Lee, C.O. Anticancer (IV) complexes for oral administration and a method of making the same. US5998648 (1999).
    • (1999) US5998648
    • Sohn, Y.S.1    Lee, S.S.2    Lee, Y.A.3    Kim, K.M.4    Lee, C.O.5
  • 52
    • 34447525351 scopus 로고    scopus 로고
    • Broadening the clinical use of platinum drug-based chemotherapy with new analogues
    • Kelland LL. Broadening the clinical use of platinum drug-based chemotherapy with new analogues: Satraplatin and picoplatin. Expert Opin Investig Drugs 2007; 16(7): 1009-21.
    • (2007) Satraplatin and Picoplatin. Expert Opin Investig Drugs , vol.16 , Issue.7 , pp. 1009-1021
    • Kelland, L.L.1
  • 55
    • 78649383421 scopus 로고    scopus 로고
    • (Accessed on: April 4, 2010)
    • http://www.cancer.gov/cancertopics/pdq/cam/NDV/HealthProfessional/ (Accessed on: April 4, 2010).
  • 56
    • 78651190570 scopus 로고
    • Newcastle disease virus as a n antineoplatic agent
    • Cassel WA, Garrett RE. Newcastle disease virus as a n antineoplatic agent. Cancer 1965; 4: 863-8.
    • (1965) Cancer , vol.4 , pp. 863-868
    • Cassel, W.A.1    Garrett, R.E.2
  • 59
    • 65649093663 scopus 로고    scopus 로고
    • Cancer/testis antigen CT45: Analysis of mRNA and protein expression in human cancer
    • Chen YT, Hsu M, Lee P, Shin SJ, Mhawech-Fauceglia P, Odunsi K, et al. Cancer/testis antigen CT45: Analysis of mRNA and protein expression in human cancer. Int J Cancer 2009; 124(12): 2893-8.
    • (2009) Int J Cancer , vol.124 , Issue.12 , pp. 2893-2898
    • Chen, Y.T.1    Hsu, M.2    Lee, P.3    Shin, S.J.4    Mhawech-Fauceglia, P.5    Odunsi, K.6
  • 60
    • 52049088540 scopus 로고    scopus 로고
    • Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission
    • Diefenbach CS, Gnjatic S, Sabbatini P, Aghajanian C, Hensley ML, Spriggs DR, et al. Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission. Clin Cancer Res 2008; 14(9): 2740-8.
    • (2008) Clin Cancer Res , vol.14 , Issue.9 , pp. 2740-2748
    • Diefenbach, C.S.1    Gnjatic, S.2    Sabbatini, P.3    Aghajanian, C.4    Hensley, M.L.5    Spriggs, D.R.6
  • 64
    • 33645087362 scopus 로고    scopus 로고
    • Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models
    • Schluep T, Hwang J, Cheng J, Heidel JD, Bartlett DW, Hollister B, et al. Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models. Clin Cancer Res 2006; 12(5): 1606-14.
    • (2006) Clin Cancer Res , vol.12 , Issue.5 , pp. 1606-1614
    • Schluep, T.1    Hwang, J.2    Cheng, J.3    Heidel, J.D.4    Bartlett, D.W.5    Hollister, B.6
  • 65
    • 67650359893 scopus 로고    scopus 로고
    • Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models
    • Numbenjapon T, Wang J, Colcher D, Schluep T, Davis ME, Duringer J, et al. Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models. Clin Cancer Res 2009; 15(13): 4365-73.
    • (2009) Clin Cancer Res , vol.15 , Issue.13 , pp. 4365-4373
    • Numbenjapon, T.1    Wang, J.2    Colcher, D.3    Schluep, T.4    Davis, M.E.5    Duringer, J.6
  • 66
    • 15444361370 scopus 로고    scopus 로고
    • Oral topotecan given once or twice daily for ten days: Aphase I pharmacology study in adult patients with solid tumors
    • Gerrits CJ, Burris H, Schellens JH, Eckardt JR, Planting AS, van der Burg ME, et al. Oral topotecan given once or twice daily for ten days: Aphase I pharmacology study in adult patients with solid tumors. Clin Cancer Res 1998; 4(5): 1153-8.
    • (1998) Clin Cancer Res , vol.4 , Issue.5 , pp. 1153-1158
    • Gerrits, C.J.1    Burris, H.2    Schellens, J.H.3    Eckardt, J.R.4    Planting, A.S.5    van der Burg, M.E.6
  • 68
    • 0032543880 scopus 로고    scopus 로고
    • Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?
    • Lever AF, Hole DJ, Gillis CR, McCallum IR, McInnes GT, MacKinnon PL, et al. Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer? Lancet 1998; 352(9123): 179-84.
    • (1998) Lancet , vol.352 , Issue.9123 , pp. 179-184
    • Lever, A.F.1    Hole, D.J.2    Gillis, C.R.3    McCallum, I.R.4    McInnes, G.T.5    Mackinnon, P.L.6
  • 69
    • 33644778610 scopus 로고    scopus 로고
    • Manipulating the angiotensin system--new approaches to the treatment of solid tumours
    • Ino K, Shibata K, Kajiyama H, Nawa A, Nomura S, Kikkawa F. Manipulating the angiotensin system--new approaches to the treatment of solid tumours. Expert Opin Biol Ther 2006; 6(3): 243-55.
    • (2006) Expert Opin Biol Ther , vol.6 , Issue.3 , pp. 243-255
    • Ino, K.1    Shibata, K.2    Kajiyama, H.3    Nawa, A.4    Nomura, S.5    Kikkawa, F.6
  • 70
    • 17644416741 scopus 로고    scopus 로고
    • Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination
    • Suganuma T, Ino K, Shibata K, Kajiyama H, Nagasaka T, Mizutani S, et al. Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination. Clin Cancer Res 2005; 11(7): 2686-94.
    • (2005) Clin Cancer Res , vol.11 , Issue.7 , pp. 2686-94
    • Suganuma, T.1    Ino, K.2    Shibata, K.3    Kajiyama, H.4    Nagasaka, T.5    Mizutani, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.