Combined in vitro tests as an alternative to in vivo eye irritation tests

ATLA Alternatives to Laboratory Animals

Volumn 38, Issue 4, 2010, Pages 303-314

  Yang, Ying ^a   Yang, Xingfen ^a,b   Zhang, Wengai ^a,b   Cai, Jinheng ^b   Xue, Jinyu ^a,b   Yang, Guangyu ^a   Tan, Xiaohua ^a   Xie, Xiaoping ^a   Xiong, Xikun ^a   Huang, Junming ^a   Guo, Xiang ^a,b  

^a GUANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Alternative methods; Eye irritation test; In vitro methods; Partial least squares

Indexed keywords

FLUORESCEIN; TRYPAN BLUE; IRRITANT AGENT; NEUTRAL RED;

ANIMAL CELL; ARTICLE; CHEMICAL ACCIDENT; CYTOTOXICITY; EYE IRRITATION; HEMOLYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; STAINING; ANIMAL; ANIMAL TESTING ALTERNATIVE; BAGG ALBINO MOUSE; CELL STRAIN 3T3; CHICKEN; CHORIOALLANTOIS; DRUG EFFECT; EGG; EYE; HUMAN; MOUSE; PREDICTION AND FORECASTING; REGRESSION ANALYSIS; TOXICITY TESTING;

ANIMALIA;

3T3 CELLS; ANIMAL TESTING ALTERNATIVES; ANIMALS; CHICKENS; CHORIOALLANTOIC MEMBRANE; EGGS; EYE; HUMANS; IRRITANTS; LEAST-SQUARES ANALYSIS; MICE; MICE, INBRED BALB C; NEUTRAL RED; PREDICTIVE VALUE OF TESTS; TOXICITY TESTS;

EID: 78349245935     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119291003800413     Document Type: Article

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