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Volumn 56, Issue 21, 2010, Pages 1693-1700

Immunologic and inflammatory reactions to exogenous stem cells: Implications for experimental studies and clinical trials for myocardial repair

Author keywords

exogenous stem cell transplantation; immune tolerance; mesenchymal stem cells; myocardial repair

Indexed keywords

CYCLOSPORIN; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYCOPHENOLIC ACID; TACROLIMUS;

EID: 78349245568     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.06.041     Document Type: Review
Times cited : (40)

References (79)
  • 1
    • 55349132417 scopus 로고    scopus 로고
    • Cardiomyocyte death and renewal in the normal and diseased heart
    • L.M. Buja, and D. Vela Cardiomyocyte death and renewal in the normal and diseased heart Cardiovasc Pathol 17 2008 349 374
    • (2008) Cardiovasc Pathol , vol.17 , pp. 349-374
    • Buja, L.M.1    Vela, D.2
  • 2
    • 33947408153 scopus 로고    scopus 로고
    • Cell-based therapy for myocardial ischemia and infarction: Pathophysiological mechanisms
    • M.A. Laflamme, S. Zbinden, S.E. Epstein, and C.E. Murry Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms Annu Rev Pathol 2 2007 307 339
    • (2007) Annu Rev Pathol , vol.2 , pp. 307-339
    • Laflamme, M.A.1    Zbinden, S.2    Epstein, S.E.3    Murry, C.E.4
  • 3
    • 39749105397 scopus 로고    scopus 로고
    • Stem-cell therapy for cardiac disease
    • V.F. Segers, and R.T. Lee Stem-cell therapy for cardiac disease Nature 451 2008 937 942
    • (2008) Nature , vol.451 , pp. 937-942
    • Segers, V.F.1    Lee, R.T.2
  • 4
    • 33947305414 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells for cardiac repair: A systematic review and meta-analysis
    • A. Abdel-Latif, R. Bolli, and I.M. Tleyjeh Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis Arch Intern Med 167 2007 989 997
    • (2007) Arch Intern Med , vol.167 , pp. 989-997
    • Abdel-Latif, A.1    Bolli, R.2    Tleyjeh, I.M.3
  • 5
    • 35349008966 scopus 로고    scopus 로고
    • Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: A collaborative systematic review and meta-analysis of controlled clinical trials
    • M.J. Lipinski, G.G. Biondi-Zoccai, and A. Abbate Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials J Am Coll Cardiol 50 2007 1761 1767
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1761-1767
    • Lipinski, M.J.1    Biondi-Zoccai, G.G.2    Abbate, A.3
  • 6
    • 67649993062 scopus 로고    scopus 로고
    • The BALANCE study: Clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction
    • M. Yousef, C.M. Schannwell, M. Kostering, T. Zeus, M. Brehm, and B.E. Strauer The BALANCE study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction J Am Coll Cardiol 53 2009 2262 2269
    • (2009) J Am Coll Cardiol , vol.53 , pp. 2262-2269
    • Yousef, M.1    Schannwell, C.M.2    Kostering, M.3    Zeus, T.4    Brehm, M.5    Strauer, B.E.6
  • 7
    • 30444435036 scopus 로고    scopus 로고
    • Human embryonic stem cells: Potential tool for achieving immunotolerance?
    • P. Menendez, C. Bueno, L. Wang, and M. Bhatia Human embryonic stem cells: potential tool for achieving immunotolerance? Stem Cell Rev 1 2005 151 158
    • (2005) Stem Cell Rev , vol.1 , pp. 151-158
    • Menendez, P.1    Bueno, C.2    Wang, L.3    Bhatia, M.4
  • 8
    • 34548075271 scopus 로고    scopus 로고
    • Immunology of stem cells and cancer stem cells
    • X.F. Yang Immunology of stem cells and cancer stem cells Cell Mol Immunol 4 2007 161 171
    • (2007) Cell Mol Immunol , vol.4 , pp. 161-171
    • Yang, X.F.1
  • 9
    • 36148960145 scopus 로고    scopus 로고
    • Embryonic stem cell transplantation for the treatment of myocardial infarction: Immune privilege or rejection
    • X. Yuan, H. Zhang, Y.J. Wei, and S.S. Hu Embryonic stem cell transplantation for the treatment of myocardial infarction: immune privilege or rejection Transpl Immunol 18 2007 88 93
    • (2007) Transpl Immunol , vol.18 , pp. 88-93
    • Yuan, X.1    Zhang, H.2    Wei, Y.J.3    Hu, S.S.4
  • 11
    • 0035997223 scopus 로고    scopus 로고
    • Embryonic stem cells share immune-privileged features relevant for tolerance induction
    • F. Fandrich, B. Dresske, M. Bader, and M. Schulze Embryonic stem cells share immune-privileged features relevant for tolerance induction J Mol Med 80 2002 343 350
    • (2002) J Mol Med , vol.80 , pp. 343-350
    • Fandrich, F.1    Dresske, B.2    Bader, M.3    Schulze, M.4
  • 12
    • 3543018487 scopus 로고    scopus 로고
    • Human embryonic stem cells possess immune-privileged properties
    • L. Li, M.L. Baroja, and A. Majumdar Human embryonic stem cells possess immune-privileged properties Stem Cells 22 2004 448 456
    • (2004) Stem Cells , vol.22 , pp. 448-456
    • Li, L.1    Baroja, M.L.2    Majumdar, A.3
  • 13
    • 35548974727 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts
    • O. Caspi, I. Huber, and I. Kehat Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts J Am Coll Cardiol 50 2007 1884 1893
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1884-1893
    • Caspi, O.1    Huber, I.2    Kehat, I.3
  • 14
    • 24644444609 scopus 로고    scopus 로고
    • Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: Role of phosphatidylinositol 3-kinase/AKT kinase
    • C. Kupatt, R. Hinkel, and M. Lamparter Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase Circulation 112 Suppl I 2005 I117 I122
    • (2005) Circulation , vol.112 , Issue.SUPPL. I
    • Kupatt, C.1    Hinkel, R.2    Lamparter, M.3
  • 16
    • 0036092735 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats
    • J.Y. Min, Y. Yang, and K.L. Converso Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats J Appl Physiol 92 2002 288 296
    • (2002) J Appl Physiol , vol.92 , pp. 288-296
    • Min, J.Y.1    Yang, Y.2    Converso, K.L.3
  • 17
    • 33845389915 scopus 로고    scopus 로고
    • Molecular imaging of human embryonic stem cells: Keeping an eye on differentiation, tumorigenicity and immunogenicity
    • K.E. van der Bogt, R.J. Swijnenburg, F. Cao, and J.C. Wu Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity Cell Cycle 5 2006 2748 2752
    • (2006) Cell Cycle , vol.5 , pp. 2748-2752
    • Van Der Bogt, K.E.1    Swijnenburg, R.J.2    Cao, F.3    Wu, J.C.4
  • 18
    • 69249203784 scopus 로고    scopus 로고
    • Effects of cell number on teratoma formation by human embryonic stem cells
    • A.S. Lee, C. Tang, and F. Cao Effects of cell number on teratoma formation by human embryonic stem cells Cell Cycle 8 2009 2608 2612
    • (2009) Cell Cycle , vol.8 , pp. 2608-2612
    • Lee, A.S.1    Tang, C.2    Cao, F.3
  • 19
    • 34247647982 scopus 로고    scopus 로고
    • Transplantation of undifferentiated murine embryonic stem cells in the heart: Teratoma formation and immune response
    • J. Nussbaum, E. Minami, and M.A. Laflamme Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response FASEB J 21 2007 1345 1357
    • (2007) FASEB J , vol.21 , pp. 1345-1357
    • Nussbaum, J.1    Minami, E.2    Laflamme, M.A.3
  • 20
    • 34648847052 scopus 로고    scopus 로고
    • Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts
    • W. Dai, L.J. Field, and M. Rubart Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts J Mol Cell Cardiol 43 2007 504 516
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 504-516
    • Dai, W.1    Field, L.J.2    Rubart, M.3
  • 21
    • 33646692132 scopus 로고    scopus 로고
    • Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells
    • M. Drukker, H. Katchman, and G. Katz Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells Stem Cells 24 2006 221 229
    • (2006) Stem Cells , vol.24 , pp. 221-229
    • Drukker, M.1    Katchman, H.2    Katz, G.3
  • 22
    • 23844520618 scopus 로고    scopus 로고
    • They are not stealthy in the heart: Embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response
    • T. Kofidis, J.L. deBruin, and M. Tanaka They are not stealthy in the heart: embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response Eur J Cardiothorac Surg 28 2005 461 466
    • (2005) Eur J Cardiothorac Surg , vol.28 , pp. 461-466
    • Kofidis, T.1    Debruin, J.L.2    Tanaka, M.3
  • 23
    • 51349086014 scopus 로고    scopus 로고
    • Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts
    • R.J. Swijnenburg, S. Schrepfer, and J.A. Govaert Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts Proc Natl Acad Sci USA 105 2008 12991 12996
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12991-12996
    • Swijnenburg, R.J.1    Schrepfer, S.2    Govaert, J.A.3
  • 24
    • 67650377709 scopus 로고    scopus 로고
    • Neural progenitors derived from human embryonic stem cells are targeted by allogeneic T and natural killer cells
    • O. Preynat-Seauve, C. de Rham, D. Tirefort, S. Ferrari-Lacraz, K.H. Krause, and J. Villard Neural progenitors derived from human embryonic stem cells are targeted by allogeneic T and natural killer cells J Cell Mol Med 13 2009 3556 3569
    • (2009) J Cell Mol Med , vol.13 , pp. 3556-3569
    • Preynat-Seauve, O.1    De Rham, C.2    Tirefort, D.3    Ferrari-Lacraz, S.4    Krause, K.H.5    Villard, J.6
  • 25
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • S. Aggarwal, and M.F. Pittenger Human mesenchymal stem cells modulate allogeneic immune cell responses Blood 105 2005 1815 1822
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 26
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • A. Bartholomew, C. Sturgeon, and M. Siatskas Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo Exp Hematol 30 2002 42 48
    • (2002) Exp Hematol , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3
  • 27
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • M. Di Nicola, C. Carlo-Stella, and M. Magni Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli Blood 99 2002 3838 3843
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 28
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • S. Glennie, I. Soeiro, P.J. Dyson, E.W. Lam, and F. Dazzi Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells Blood 105 2005 2821 2827
    • (2005) Blood , vol.105 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.4    Dazzi, F.5
  • 29
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • DOI 10.1111/j.1365-2796.2007.01844.x
    • K. Le Blanc, and O. Ringden Immunomodulation by mesenchymal stem cells and clinical experience J Intern Med 262 2007 509 525 (Pubitemid 47620502)
    • (2007) Journal of Internal Medicine , vol.262 , Issue.5 , pp. 509-525
    • Le Blanc, K.1    Ringden, O.2
  • 30
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • B. Maitra, E. Szekely, and K. Gjini Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation Bone Marrow Transplant 33 2004 597 604
    • (2004) Bone Marrow Transplant , vol.33 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3
  • 31
    • 47949099102 scopus 로고    scopus 로고
    • Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens
    • F. Morandi, L. Raffaghello, and G. Bianchi Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens Stem Cells 26 2008 1275 1287
    • (2008) Stem Cells , vol.26 , pp. 1275-1287
    • Morandi, F.1    Raffaghello, L.2    Bianchi, G.3
  • 32
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • A.J. Nauta, and W.E. Fibbe Immunomodulatory properties of mesenchymal stromal cells Blood 110 2007 3499 3506
    • (2007) Blood , vol.110 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 34
    • 77951748559 scopus 로고    scopus 로고
    • Stem cells in cardiac repair in an inflammatory microenvironment
    • P. Rameshwar, H. Qiu, and S.F. Vatner Stem cells in cardiac repair in an inflammatory microenvironment Minerva Cardioangiol 58 2010 127 146
    • (2010) Minerva Cardioangiol , vol.58 , pp. 127-146
    • Rameshwar, P.1    Qiu, H.2    Vatner, S.F.3
  • 35
    • 15044348816 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms
    • I. Rasmusson, O. Ringden, B. Sundberg, and K. Le Blanc Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms Exp Cell Res 305 2005 33 41
    • (2005) Exp Cell Res , vol.305 , pp. 33-41
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 36
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • A.J. Nauta, G. Westerhuis, A.B. Kruisselbrink, E.G. Lurvink, R. Willemze, and W.E. Fibbe Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting Blood 108 2006 2114 2120
    • (2006) Blood , vol.108 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.4    Willemze, R.5    Fibbe, W.E.6
  • 37
    • 52049101144 scopus 로고    scopus 로고
    • Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation
    • T.B. Prigozhina, S. Khitrin, G. Elkin, O. Eizik, S. Morecki, and S. Slavin Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation Exp Hematol 36 2008 1370 1376
    • (2008) Exp Hematol , vol.36 , pp. 1370-1376
    • Prigozhina, T.B.1    Khitrin, S.2    Elkin, G.3    Eizik, O.4    Morecki, S.5    Slavin, S.6
  • 38
    • 33744917000 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice
    • M. Sudres, F. Norol, and A. Trenado Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice J Immunol 176 2006 7761 7767
    • (2006) J Immunol , vol.176 , pp. 7761-7767
    • Sudres, M.1    Norol, F.2    Trenado, A.3
  • 39
    • 72849151523 scopus 로고    scopus 로고
    • Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells
    • L. Zangi, R. Margalit, and S. Reich-Zeliger Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells Stem Cells 27 2009 2865 2874
    • (2009) Stem Cells , vol.27 , pp. 2865-2874
    • Zangi, L.1    Margalit, R.2    Reich-Zeliger, S.3
  • 40
    • 33947200410 scopus 로고    scopus 로고
    • Murine bone marrow stromal progenitor cells elicit an in vivo cellular and humoral alloimmune response
    • A.T. Badillo, K.J. Beggs, E.H. Javazon, J.C. Tebbets, and A.W. Flake Murine bone marrow stromal progenitor cells elicit an in vivo cellular and humoral alloimmune response Biol Blood Marrow Transplant 13 2007 412 422
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 412-422
    • Badillo, A.T.1    Beggs, K.J.2    Javazon, E.H.3    Tebbets, J.C.4    Flake, A.W.5
  • 41
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • N. Eliopoulos, J. Stagg, L. Lejeune, S. Pommey, and J. Galipeau Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice Blood 106 2005 4057 4065
    • (2005) Blood , vol.106 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 42
    • 34147174435 scopus 로고    scopus 로고
    • Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo
    • A.J. Poncelet, J. Vercruysse, A. Saliez, and P. Gianello Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo Transplantation 83 2007 783 790
    • (2007) Transplantation , vol.83 , pp. 783-790
    • Poncelet, A.J.1    Vercruysse, J.2    Saliez, A.3    Gianello, P.4
  • 43
    • 53249095498 scopus 로고    scopus 로고
    • The immune system and cardiac repair
    • N.G. Frangogiannis The immune system and cardiac repair Pharmacol Res 58 2008 88 111
    • (2008) Pharmacol Res , vol.58 , pp. 88-111
    • Frangogiannis, N.G.1
  • 44
    • 24644519816 scopus 로고    scopus 로고
    • Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium
    • R.J. Swijnenburg, M. Tanaka, and H. Vogel Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium Circulation 112 2005 I166 I172
    • (2005) Circulation , vol.112
    • Swijnenburg, R.J.1    Tanaka, M.2    Vogel, H.3
  • 45
    • 34548044258 scopus 로고    scopus 로고
    • Potential risks of bone marrow cell transplantation into infarcted hearts
    • M. Breitbach, T. Bostani, and W. Roell Potential risks of bone marrow cell transplantation into infarcted hearts Blood 110 2007 1362 1369
    • (2007) Blood , vol.110 , pp. 1362-1369
    • Breitbach, M.1    Bostani, T.2    Roell, W.3
  • 46
    • 67449107988 scopus 로고    scopus 로고
    • A transformed cell population derived from cultured mesenchymal stem cells has no functional effect after transplantation into the injured heart
    • D. Furlani, W. Li, and E. Pittermann A transformed cell population derived from cultured mesenchymal stem cells has no functional effect after transplantation into the injured heart Cell Transplant 18 2009 319 331
    • (2009) Cell Transplant , vol.18 , pp. 319-331
    • Furlani, D.1    Li, W.2    Pittermann, E.3
  • 47
    • 42749088243 scopus 로고    scopus 로고
    • Allogenic mesenchymal stem cell transplantation has a therapeutic effect in acute myocardial infarction in rats
    • Y. Imanishi, A. Saito, and H. Komoda Allogenic mesenchymal stem cell transplantation has a therapeutic effect in acute myocardial infarction in rats J Mol Cell Cardiol 44 2008 662 671
    • (2008) J Mol Cell Cardiol , vol.44 , pp. 662-671
    • Imanishi, Y.1    Saito, A.2    Komoda, H.3
  • 48
    • 58149483375 scopus 로고    scopus 로고
    • Improvement in cardiac function after bone marrow cell thearpy is associated with an increase in myocardial inflammation
    • J. Sun, S.H. Li, and S.M. Liu Improvement in cardiac function after bone marrow cell thearpy is associated with an increase in myocardial inflammation Am J Physiol Heart Circ Physiol 296 2009 H43 H50
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Sun, J.1    Li, S.H.2    Liu, S.M.3
  • 49
    • 2342427573 scopus 로고    scopus 로고
    • Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium
    • K.H. Grinnemo, A. Mansson, and G. Dellgren Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium J Thorac Cardiovasc Surg 127 2004 1293 1300
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 1293-1300
    • Grinnemo, K.H.1    Mansson, A.2    Dellgren, G.3
  • 50
    • 0033955147 scopus 로고    scopus 로고
    • Autologous porcine heart cell transplantation improved heart function after a myocardial infarction
    • R.K. Li, R.D. Weisel, and D.A. Mickle Autologous porcine heart cell transplantation improved heart function after a myocardial infarction J Thorac Cardiovasc Surg 119 2000 62 68
    • (2000) J Thorac Cardiovasc Surg , vol.119 , pp. 62-68
    • Li, R.K.1    Weisel, R.D.2    Mickle, D.A.3
  • 51
    • 68749109482 scopus 로고    scopus 로고
    • Cell therapy with autologous bone marrow mononuclear stem cells is associated with superior cardiac recovery compared with use of nonmodified mesenchymal stem cells in a canine model of chronic myocardial infarction
    • M. Mathieu, J. Bartunek, and B. El Oumeiri Cell therapy with autologous bone marrow mononuclear stem cells is associated with superior cardiac recovery compared with use of nonmodified mesenchymal stem cells in a canine model of chronic myocardial infarction J Thorac Cardiovasc Surg 138 2009 646 653
    • (2009) J Thorac Cardiovasc Surg , vol.138 , pp. 646-653
    • Mathieu, M.1    Bartunek, J.2    El Oumeiri, B.3
  • 52
    • 0036266426 scopus 로고    scopus 로고
    • Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects
    • J.G. Shake, P.J. Gruber, and W.A. Baumgartner Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects Ann Thorac Surg 73 2002 1919 1925 discussion 1926
    • (2002) Ann Thorac Surg , vol.73 , pp. 1919-1925
    • Shake, J.G.1    Gruber, P.J.2    Baumgartner, W.A.3
  • 53
    • 24344467861 scopus 로고    scopus 로고
    • Left ventricular functional recovery with percutaneous, transvascular direct myocardial delivery of bone marrow-derived cells
    • C.A. Thompson, V.K. Reddy, and A. Srinivasan Left ventricular functional recovery with percutaneous, transvascular direct myocardial delivery of bone marrow-derived cells J Heart Lung Transplant 24 2005 1385 1392
    • (2005) J Heart Lung Transplant , vol.24 , pp. 1385-1392
    • Thompson, C.A.1    Reddy, V.K.2    Srinivasan, A.3
  • 54
    • 60849116694 scopus 로고    scopus 로고
    • Histopathological study of healing after allogenic mesenchymal stem cell delivery in myocardial infarction in dogs
    • D.C. Vela, G.V. Silva, and J.A. Assad Histopathological study of healing after allogenic mesenchymal stem cell delivery in myocardial infarction in dogs J Histochem Cytochem 57 2009 167 176
    • (2009) J Histochem Cytochem , vol.57 , pp. 167-176
    • Vela, D.C.1    Silva, G.V.2    Assad, J.A.3
  • 55
    • 23844475067 scopus 로고    scopus 로고
    • Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction
    • L.C. Amado, A.P. Saliaris, and K.H. Schuleri Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction Proc Natl Acad Sci U S A 102 2005 11474 11479
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11474-11479
    • Amado, L.C.1    Saliaris, A.P.2    Schuleri, K.H.3
  • 56
    • 38349112704 scopus 로고    scopus 로고
    • A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction
    • S.M. Hashemi, S. Ghods, and F.D. Kolodgie A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction Eur Heart J 29 2008 251 259
    • (2008) Eur Heart J , vol.29 , pp. 251-259
    • Hashemi, S.M.1    Ghods, S.2    Kolodgie, F.D.3
  • 57
    • 29344465127 scopus 로고    scopus 로고
    • Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction
    • R.R. Makkar, M.J. Price, and M. Lill Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction J Cardiovasc Pharmacol Ther 10 2005 225 233
    • (2005) J Cardiovasc Pharmacol Ther , vol.10 , pp. 225-233
    • Makkar, R.R.1    Price, M.J.2    Lill, M.3
  • 58
    • 70349785585 scopus 로고    scopus 로고
    • Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction
    • J.A. Dixon, R.C. Gorman, and R.E. Stroud Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction Circulation 120 2009 S220 S229
    • (2009) Circulation , vol.120
    • Dixon, J.A.1    Gorman, R.C.2    Stroud, R.E.3
  • 59
    • 60449118700 scopus 로고    scopus 로고
    • Allogeneic mesenchymal precursor cell therapy to limit remodeling after myocardial infarction: The effect of cell dosage
    • H. Hamamoto, J.H. Gorman 3rd, and L.P. Ryan Allogeneic mesenchymal precursor cell therapy to limit remodeling after myocardial infarction: the effect of cell dosage Ann Thorac Surg 87 2009 794 801
    • (2009) Ann Thorac Surg , vol.87 , pp. 794-801
    • Hamamoto, H.1    Gorman III, J.H.2    Ryan, L.P.3
  • 60
    • 77953619394 scopus 로고    scopus 로고
    • The impact of timing on the safety of transendocardial delivery of mesenchymal precursor stem cells following acute myocardial infarction (abstr)
    • M.R. Fernandes, G.V. Silva, and C.O. Cardoso The impact of timing on the safety of transendocardial delivery of mesenchymal precursor stem cells following acute myocardial infarction (abstr) J Am Coll Cardiol 53 Suppl 2009 A311
    • (2009) J Am Coll Cardiol , vol.53 , Issue.SUPPL. , pp. 311
    • Fernandes, M.R.1    Silva, G.V.2    Cardoso, C.O.3
  • 61
    • 33646535285 scopus 로고    scopus 로고
    • In vivo echocardiographic imaging of transplanted human adult stem cells in the myocardium labeled with clinically applicable CliniMACS nanoparticles
    • C. Bara, A. Ghodsizad, and M. Niehaus In vivo echocardiographic imaging of transplanted human adult stem cells in the myocardium labeled with clinically applicable CliniMACS nanoparticles J Am Soc Echocardiogr 19 2006 563 568
    • (2006) J Am Soc Echocardiogr , vol.19 , pp. 563-568
    • Bara, C.1    Ghodsizad, A.2    Niehaus, M.3
  • 62
    • 58349097296 scopus 로고    scopus 로고
    • Transplanted human cord blood-derived unrestricted somatic stem cells improve left-ventricular function and prevent left-ventricular dilation and scar formation after acute myocardial infarction
    • A. Ghodsizad, M. Niehaus, and G. Kogler Transplanted human cord blood-derived unrestricted somatic stem cells improve left-ventricular function and prevent left-ventricular dilation and scar formation after acute myocardial infarction Heart 95 2009 27 35
    • (2009) Heart , vol.95 , pp. 27-35
    • Ghodsizad, A.1    Niehaus, M.2    Kogler, G.3
  • 63
    • 0842324789 scopus 로고    scopus 로고
    • Effectiveness of transient immunosuppression using cyclosporine for xenomyoblast transplantation for cardiac repair
    • H. Haider, S.J. Jiang, L. Ye, S. Aziz, P.K. Law, and E.K. Sim Effectiveness of transient immunosuppression using cyclosporine for xenomyoblast transplantation for cardiac repair Transplant Proc 36 2004 232 235
    • (2004) Transplant Proc , vol.36 , pp. 232-235
    • Haider, H.1    Jiang, S.J.2    Ye, L.3    Aziz, S.4    Law, P.K.5    Sim, E.K.6
  • 64
    • 24644459322 scopus 로고    scopus 로고
    • Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials
    • D. Hou, E.A. Youssef, and T.J. Brinton Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials Circulation 112 Suppl I 2005 I150 I156
    • (2005) Circulation , vol.112 , Issue.SUPPL. I
    • Hou, D.1    Youssef, E.A.2    Brinton, T.J.3
  • 65
    • 24644522767 scopus 로고    scopus 로고
    • Cell transplantation improves ventricular function after a myocardial infarction: A preclinical study of human unrestricted somatic stem cells in a porcine model
    • B.O. Kim, H. Tian, and K. Prasongsukarn Cell transplantation improves ventricular function after a myocardial infarction: a preclinical study of human unrestricted somatic stem cells in a porcine model Circulation 112 Suppl I 2005 I96 I104
    • (2005) Circulation , vol.112 , Issue.SUPPL. I
    • Kim, B.O.1    Tian, H.2    Prasongsukarn, K.3
  • 66
    • 78349278975 scopus 로고    scopus 로고
    • The effect of human unrestricted somatic stem cells on swine after acute myocardial infarction: Insight into xenogenic model in cell therapy research (abstr)
    • G.V. Silva, Y. Zheng, and M.R. Fernandes The effect of human unrestricted somatic stem cells on swine after acute myocardial infarction: insight into xenogenic model in cell therapy research (abstr) J Am Coll Cardiol 53 Suppl 2009 A311
    • (2009) J Am Coll Cardiol , vol.53 , Issue.SUPPL. , pp. 311
    • Silva, G.V.1    Zheng, Y.2    Fernandes, M.R.3
  • 67
    • 15344349445 scopus 로고    scopus 로고
    • Quantitative analysis of survival of transplanted smooth muscle cells with real-time polymerase chain reaction
    • T. Yasuda, R.D. Weisel, C. Kiani, D.A. Mickle, M. Maganti, and R.K. Li Quantitative analysis of survival of transplanted smooth muscle cells with real-time polymerase chain reaction J Thorac Cardiovasc Surg 129 2005 904 911
    • (2005) J Thorac Cardiovasc Surg , vol.129 , pp. 904-911
    • Yasuda, T.1    Weisel, R.D.2    Kiani, C.3    Mickle, D.A.4    Maganti, M.5    Li, R.K.6
  • 68
    • 67649865604 scopus 로고    scopus 로고
    • Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy
    • Y. Yeghiazarians, Y. Zhang, and M. Prasad Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy Mol Ther 17 2009 1250 1256
    • (2009) Mol Ther , vol.17 , pp. 1250-1256
    • Yeghiazarians, Y.1    Zhang, Y.2    Prasad, M.3
  • 69
  • 70
    • 58149341592 scopus 로고    scopus 로고
    • Inhibition of humoral response to allogeneic porcine mesenchymal stem cell with 12 days of tacrolimus
    • A.J. Poncelet, Y. Nizet, J. Vercruysse, A.L. Hiel, A. Saliez, and P. Gianello Inhibition of humoral response to allogeneic porcine mesenchymal stem cell with 12 days of tacrolimus Transplantation 86 2008 1586 1595
    • (2008) Transplantation , vol.86 , pp. 1586-1595
    • Poncelet, A.J.1    Nizet, Y.2    Vercruysse, J.3    Hiel, A.L.4    Saliez, A.5    Gianello, P.6
  • 72
    • 43449126812 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents
    • L.W. van Laake, R. Passier, P.A. Doevendans, and C.L. Mummery Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents Circ Res 102 2008 1008 1010
    • (2008) Circ Res , vol.102 , pp. 1008-1010
    • Van Laake, L.W.1    Passier, R.2    Doevendans, P.A.3    Mummery, C.L.4
  • 73
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • K. Takahashi, K. Tanabe, and M. Ohnuki Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 74
    • 61949300076 scopus 로고    scopus 로고
    • Functional cardiomyocytes derived from human induced pluripotent stem cells
    • J. Zhang, G.F. Wilson, and A.G. Soerens Functional cardiomyocytes derived from human induced pluripotent stem cells Circ Res 104 2009 e30 e41
    • (2009) Circ Res , vol.104
    • Zhang, J.1    Wilson, G.F.2    Soerens, A.G.3
  • 75
    • 77955212526 scopus 로고    scopus 로고
    • The first US study to assess the feasibility and safety of endocardial delivery of allogeneic mesenchymal stem precursor cells in patient with heart failure: Three month interim analysis (abstr)
    • N. Dib, T. Henry, and A. DeMaria The first US study to assess the feasibility and safety of endocardial delivery of allogeneic mesenchymal stem precursor cells in patient with heart failure: three month interim analysis (abstr) Circulation 120 Suppl 2009 810
    • (2009) Circulation , vol.120 , Issue.SUPPL. , pp. 810
    • Dib, N.1    Henry, T.2    Demaria, A.3
  • 76
    • 70549103270 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction
    • J.M. Hare, J.H. Traverse, and T.D. Henry A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction J Am Coll Cardiol 54 2009 2277 2286
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2277-2286
    • Hare, J.M.1    Traverse, J.H.2    Henry, T.D.3
  • 78
    • 65649147929 scopus 로고    scopus 로고
    • Medicine: A history lesson for stem cells
    • J.M. Wilson Medicine A history lesson for stem cells Science 324 2009 727 728
    • (2009) Science , vol.324 , pp. 727-728
    • Wilson, J.M.1
  • 79
    • 67649995222 scopus 로고    scopus 로고
    • FDA regulation of stem cell-based products
    • D.W. Fink Jr FDA regulation of stem cell-based products Science 324 2009 1662 1663
    • (2009) Science , vol.324 , pp. 1662-1663
    • Fink Jr., D.W.1


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