ADULT;
CASE REPORT;
DESENSITIZATION;
DRUG DOSE ESCALATION;
DRUG DOSE INCREASE;
DRUG ERYTHROCYTE LEVEL;
DRUG HYPERSENSITIVITY;
DRUG SAFETY;
DRUG TOLERABILITY;
DRUG WITHDRAWAL;
HEPATITIS;
HUMAN;
HYPERSENSITIVITY HEPATITIS;
LETTER;
LIVER FUNCTION TEST;
MALE;
PORTAL HYPERTENSION;
PRIORITY JOURNAL;
SIDE EFFECT;
TREATMENT OUTCOME;
ULCERATIVE COLITIS;
Thiopurine-induced liver injury in patients with inflammatory bowel disease: A systematic review
Gisbert JP, González-Lama Y, Maté J,. Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review. Am J Gastroenterol. 2007; 102: 1518-1527.
Liver injury in inflammatory bowel disease: Long-term follow-up study of 786 patients
Gisbert JP, Luna M, González-Lama Y, et al. Liver injury in inflammatory bowel disease: long-term follow-up study of 786 patients. Inflamm Bowel Dis. 2007; 13: 1106-1114.
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology. 2000; 118: 705-713.
Hepatotoxicity of 6-mercaptopurine (6-MP) and azathioprine (AZA) in adult IBD patients
Shaye OA, Yadegari M, Abreu MT, Poordad F, et al. Hepatotoxicity of 6-mercaptopurine (6-MP) and azathioprine (AZA) in adult IBD patients. Am J Gastroenterol. 2007; 102: 2488-2494.
Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity
McGovern DP, Travis SP, Duley J, et al. Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity. Gastroenterology. 2002; 122: 838-839.
Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease
Hindorf U, Johansson M, Eriksson A, et al. Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2009; 29: 654-661.
Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease
Gearry RB, Barclay ML, Burt MJ, et al. Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease. Pharmacoepidemiol Drug Saf. 2004; 13: 563-567.
Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease
Lees CW, Maan AK, Hansoti B, et al. Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2008; 27: 220-227.