Bone morphogenetic protein-7 enhances cementoblast function in vitro

Journal of Periodontology

Volumn 81, Issue 11, 2010, Pages 1663-1674

  Hakki, Sema S ^a   Foster, Brian L ^b   Nagatomo, Kanako J ^b   Bozkurt, S Buket ^a   Hakki, Erdogan E ^a   Somerman, Martha J ^b   Nohutcu, Rahime M ^c  

^a SELCUK UNIVERSITY   (Turkey)

^b UNIVERSITY OF WASHINGTON   (United States)

^c HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Bone morphogenetic protein 7; Collagen; Dental cementum; Extracellular matrix; Matrix metalloproteinases; Regeneration

Indexed keywords

BMP7 PROTEIN, MOUSE; CELL ADHESION MOLECULE; COLLAGEN; INTEGRIN; MATRIX METALLOPROTEINASE; MMP3 PROTEIN, MOUSE; OSTEOCALCIN; OSTEOGENIC PROTEIN 1; OSTEOPONTIN; RUNX2 PROTEIN, MOUSE; SCLEROPROTEIN; SPP1 PROTEIN, MOUSE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR RUNX2;

ANIMAL; ARTICLE; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL LINE; CEMENTUM; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MOUSE; PROTEIN MICROARRAY; TIME; TOOTH ROOT; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 7; CALCIFICATION, PHYSIOLOGIC; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL LINE; COLLAGEN; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DENTAL CEMENTUM; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTEGRINS; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASES; MICE; OSTEOCALCIN; OSTEOPONTIN; PROTEIN ARRAY ANALYSIS; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASES; TOOTH ROOT; UP-REGULATION;

EID: 78249240352     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2010.100074     Document Type: Article

References (57)

1. D'Errico JA, MacNeil RL, Takata T, Berry J, Strayhorn C, Somerman MJ. Expression of bone associated markers by tooth root lining cells, in situ and in vitro. Bone 1997;20:117-126.
2. Saygin NE, Giannobile WV, Somerman MJ. Molecular and cell biology of cementum. Periodontol 2000 2000;24:73-98.
3. Zeichner-David M. Regeneration of periodontal tissues: Cementogenesis revisited. Periodontol 2000 2006;41:196-217.
4. Ripamonti U, Petit JC. Bone morphogenetic proteins, cementogenesis, myoblastic stem cells and the induction of periodontal tissue regeneration. Cytokine Growth Factor Rev 2009;20:489-499.
5. Ripamonti U, Renton L. Bone morphogenetic proteins and the induction of periodontal tissue regeneration. Periodontol 2000 2006;41:73-87.
6. Kishigami S, Mishina Y. BMP signaling and early embryonic patterning. Cytokine Growth Factor Rev 2005;16:265-278.
7. Thesleff I, Sharpe P. Signalling networks regulating dental development. Mech Dev 1997;67:111-123.
8. Ripamonti U. Bone induction by recombinant human osteogenic protein-1 (hOP-1, BMP-7) in the primate Papio ursinus with expression of mRNA of gene products of the TGF-β superfamily. J Cell Mol Med 2005;9:911-928.
9. Ripamonti U, Reddi AH. Periodontal regeneration: Potential role of bone morphogenetic proteins. J Periodontal Res 1994;29:225-235.
10. Gautschi OP, Frey SP, Zellweger R. Bone morphogenetic proteins in clinical applications. ANZ J Surg 2007;77:626-631.
11. Giannoudis PV, Tzioupis C. Clinical applications of BMP-7: The UK perspective. Injury 2005;36(Suppl. 3): S47-S50.
12. Thomadakis G, Ramoshebi LN, Crooks J, Rueger DC, Ripamonti U. Immunolocalization of bone morphogenetic protein-2 and-3 and osteogenic protein-1 during murine tooth root morphogenesis and in other craniofacial structures. Eur J Oral Sci 1999;107:368-377.
13. Aberg T, Wozney J, Thesleff I. Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn 1997;210:383-396.
14. Ripamonti U. Soluble osteogenic molecular signals and the induction of bone formation. Biomaterials 2006;27:807-822.
15. Ripamonti U, Heliotis M, van den Heever B, Reddi AH. Bone morphogenetic proteins induce periodontal regeneration in the baboon (Papio ursinus). J Periodontal Res 1994;29:439-445.
16. Ripamonti U, Heliotis M, Rueger DC, Sampath TK. Induction of cementogenesis by recombinant human osteogenic protein-1 (hop-1/bmp-7) in the baboon (Papio ursinus). Arch Oral Biol 1996;41:121-126.
17. Ripamonti U, Van Den Heever B, Crooks J, et al. Longterm evaluation of bone formation by osteogenic protein 1 in the baboon and relative efficacy of bonederived bone morphogenetic proteins delivered by irradiated xenogeneic collagenous matrices. J Bone Miner Res 2000;15:1798-1809.
18. Ripamonti U, Crooks J, Petit J-C, Rueger DC. Periodontal tissue regeneration by combined applications of recombinant human osteogenic protein-1 and bone morphogenetic protein-2. A pilot study in Chacma baboons (Papio ursinus). Eur J Oral Sci 2001;109:241-248.
19. Ripamonti U, Crooks J, Teare J, Petit J-C, Rueger DC. Periodontal tissue regeneration by recombinant human osteogenic protein-1 in periodontally induced furcation defects of the primate Papio ursinus. S Afr J Sci 2002;98:361-368.
20. Ripamonti U, Teare J, Petit J-C. Pleiotropism of bone morphogenetic proteins: From bone induction to cementogenesis and periodontal ligament regeneration. J Int Acad Periodontol 2006;8:23-32.
21. Ripamonti U, Herbst N-N, Ramoshebi LN. Bone morphogenetic proteins in craniofacial and periodontal tissue engineering: Experimental studies in the nonhuman primate Papio ursinus. Cytokine Growth Factor Rev 2005;16:357-368.
22. Choi S-H, Kim C-K, Cho K-S, et al. Effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) on healing in 3-wall intrabony defects in dogs. J Periodontol 2002;73:63-72.
23. Giannobile WV, Ryan S, Shih MS, Su DL, Kaplan PL, Chan TC. Recombinant human osteogenic protein-1 (OP-1) stimulates periodontal wound healing in class III furcation defects. J Periodontol 1998;69:129-137.
24. Nakashima M, Reddi AH. The application of bone morphogenetic proteins to dental tissue engineering. Nat Biotechnol 2003;21:1025-1032.
25. Sigurdsson TJ, Lee MB, Kubota K, Turek TJ, Wozney JM, Wikesjö UM. Periodontal repair in dogs: Recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration. J Periodontol 1995;66:131-138.
26. Sampath TK, Maliakal JC, Hauschka PV, et al. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem 1992;267:20352-20362.
27. Chaudhary LR, Hofmeister AM, Hruska KA. Differential growth factor control of bone formation through osteoprogenitor differentiation. Bone 2004;34:402-411.
28. D'Errico JA, Ouyang H, Berry JE, et al. Immortalized cementoblasts and periodontal ligament cells in culture. Bone 1999;25:39-47.
29. Yeh LC, Tsai AD, Lee JC. Osteogenic protein-1 (OP-1, BMP-7) induces osteoblastic cell differentiation of the pluripotent mesenchymal cell line C2C12. J Cell Biochem 2002;87:292-304.
30. Hakki SS, Nohutcu RM, Hakki EE, Berry JE, Akkaya MS, Somerman MJ. Dexamethasone and basic-fibroblast growth factor regulate markers of mineralization in cementoblasts in vitro. J Periodontol 2005;76:1550-1558.
31. Hakki SS, Balci B, Hakki EE, Yilmaz E, Nohutcu RM. Identification of the difference in extracellular matrix and adhesion molecules of cultured human gingival fibroblasts versus juvenile hyaline fibromatosis gingival fibroblasts using cDNA microarray analysis. J Periodontol 2005;76:2244-2253.
32. Belton RJ Jr., Chen L, Mesquita FS, Nowak RA. Basigin-2 is a cell surface receptor for soluble basigin ligand. J Biol Chem 2008;283:17805-17814.
33. Huet E, Vallée B, Szul D, et al. Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: Implications in tissue remodeling. FASEB J 2008;22:1144-1154.
34. Schwab W, Harada H, Goetz W, et al. Immunocytochemical and biochemical detection of EMMPRIN in the rat tooth germ: Differentiation-dependent coexpression with MMPs and co-localization with caveolin-1 in membrane rafts of dental epithelial cells. Histochem Cell Biol 2007;128:195-203.
35. Surlin P, Rauten AM, Mateescu GO, Oprea B, Marisx M, Manolea H. The involvement of metalloproteinases and their tissular inhibitors in the processes of periodontal orthodontic remodeling. Rom J Morphol Embryol 2009;50:181-184.
36. Sone S, Nakamura M, Maruya Y, et al. Expression of versican and ADAMTS during rat tooth eruption. J Mol Histol 2005;36:281-288.
37. de Haar SF, Tigchelaar-Gutter W, Everts V, Beertsen W. Structure of the periodontium in cathepsin C-deficient mice. Eur J Oral Sci 2006;114:171-173.
38. Sasaki T, Ueno-Matsuda E. Immunocytochemical localization of cathepsins B and G in odontoclasts of human deciduous teeth. J Dent Res 1992;71:1881-1884.
39. Lin WL, Chien HH, Cho MI. N-cadherin expression during periodontal ligament cell differentiation in vitro. J Periodontol 1999;70:1039-1045.
40. Chen Y, Alman BA. Wnt pathway, an essential role in bone regeneration. J Cell Biochem 2009;106:353-362.
41. Nemoto E, Koshikawa Y, Kanaya S, et al. Wnt signaling inhibits cementoblast differentiation and promotes proliferation. Bone 2009;44:805-812.
42. Liu F, Chu EY, Watt B, et al. Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol 2008;313:210-224.
43. Rooker SM, Liu B, Helms JA. Role of Wnt signaling in the biology of the periodontium. Dev Dyn 2010;239:140-147.
44. Fedarko NS, Jain A, Karadag A, Fisher LW. Three small integrin binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J 2004;18:734-736.
45. Ripamonti U, Ferretti C, Heliotis M. Soluble and insoluble signals and the induction of bone formation: Molecular therapeutics recapitulating development. J Anat 2006;209:447-468.
46. Zhao M, Berry JE, Somerman MJ. Bone morphogenetic protein-2 inhibits differentiation and mineralization of cementoblasts in vitro. J Dent Res 2003;82:23-27.
47. Bais MV, Wigner N, Young M, et al. BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. Bone 2009;45:254-266.
48. Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT. Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblastspecific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res 2002;17:101-110.
49. Harris NL, Rattray KR, Tye CE, et al. Functional analysis of bone sialoprotein: Identification of the hydroxyapatite-nucleating and cell-binding domains by recombinant peptide expression and sitedirected mutagenesis. Bone 2000;27:795-802.
50. Marom R, Shur I, Solomon R, Benayahu D. Characterization of adhesion and differentiation markers of osteogenic marrow stromal cells. J Cell Physiol 2005;202:41-48.
51. Ducy P, Starbuck M, Priemel M, et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes Dev 1999;13:1025-1036.
52. Bronckers AL, Engelse MA, Cavender A, Gaikwad J, D'Souza RN. Cell-specific patterns of Cbfa1 mRNA and protein expression in postnatal murine dental tissues. Mech Dev 2001;101:255-258.
53. Gersbach CA, Byers BA, Pavlath GK, García AJ. Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp Cell Res 2004;300:406-417.
54. Phimphilai M, Zhao Z, Boules H, Roca H, Franceschi RT. BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype. J Bone Miner Res 2006;21:637-646.
55. Sorsa T, Tjäderhane L, Salo T. Matrix metalloproteinases (MMPs) in oral diseases. Oral Dis 2004;10:311-318.
56. Holmen SL, Zylstra CR, Mukherjee A, et al. Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem 2005;280:21162-21168.
57. Chen Y, Whetstone HC, Youn A, et al. Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. J Biol Chem 2007;282:526-533.