Relocation of aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor

Angewandte Chemie - International Edition

Volumn 49, Issue 44, 2010, Pages 8228-8231

  Tcherniuk, Sergey ^b   Skoufias, Dimitrios A ^b   Labriere, Christophe ^c   Rath, Oliver ^a   Gueritte, Franáoise ^c   Guillou, Catherine ^c   Kozielski, Frank ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^c INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

Author keywords

Antimitotics; Antitumor agents; Cytokinesis; Inhibitors; Kinesin

Indexed keywords

ANTI-TUMOR AGENTS; ANTIMITOTICS; CYTOKINESIS; INHIBITORS; KINESINS;

CHROMOSOMES;

2 (1H INDOL 3 YL) 3 (PYRIDIN 3 YL)ACRYLONITRILE; 2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)ACRYLONITRILE; ACRYLONITRILE; AURORA KINASE; BIRC5 PROTEIN, HUMAN; DRUG DERIVATIVE; INDOLE DERIVATIVE; KIF20A PROTEIN, HUMAN; KINESIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CENTROMERE; DRUG ANTAGONISM; METABOLISM; MITOSIS SPINDLE;

ACRYLONITRILE; CENTROMERE; INDOLES; KINESIN; MICROTUBULE-ASSOCIATED PROTEINS; MITOTIC SPINDLE APPARATUS; PROTEIN-SERINE-THREONINE KINASES;

EID: 78249232298     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201003254     Document Type: Article

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