In vivo confocal microscopy of conjunctival goblet cells in patients with Sjögren's syndrome dry eye

British Journal of Ophthalmology

Volumn 94, Issue 11, 2010, Pages 1454-1458

  Hong, Jiaxu ^a   Zhu, Wenqing ^a   Zhuang, Hong ^a   Xu, Jianjiang ^a   Sun, Xinghuai ^a   Le, Qihua ^a   Li, Gang ^a   Wang, Yan ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CELL DENSITY; CELL STRUCTURE; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONJUNCTIVA; CYTOLOGY; DRY EYE; FEMALE; GOBLET CELL; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SCHIRMER TEST; SJOEGREN SYNDROME; TEAR FILM; BIOPSY; CELL COUNT; LACRIMAL FLUID; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

BIOPSY; CELL COUNT; CONJUNCTIVA; FEMALE; GOBLET CELLS; HUMANS; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; SJOGREN'S SYNDROME; TEARS;

EID: 78149490053     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjo.2009.161059     Document Type: Article

References (26)

1. Li DQ, Chen Z, Song XJ, et al. Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells. Invest Ophthalmol Vis Sci 2004;45:4302-11.
2. De Paiva CS, Corrales RM, Villarreal AL, et al. Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res 2006;83:526-35.
3. Niederkorn JY, Stern ME, Pflugfelder SC, et al. Dessicating stress induces T-cell mediated Sjögren's syndrome-like lacrimal keratoconjunctivitis sicca. J Immunol 2006;176:3950-7.
4. Yeh S, Song XJ, Farley W, et al. Apoptosis of ocular surface cells in experimentally induced dry eye. Invest Ophthalmol Vis Sci 2003;44:124-9.
5. Zhao H, Jumblatt JE, Wood TO, et al. Quantication of MUC5AC protein in human tears. Cornea 2001;20:873-7. (Pubitemid 33029489)
6. Argüeso P, Balaram M, Spurr-Michaud S, et al. Decreased levels of the goblet cell mucin MUC5AC in tears of Sjögren's syndrome patients. Invest Ophthalmol Vis Sci 2003;43:1004-11.
7. Calonge M, Diebold Y, Sáez V, et al. Impression cytology of the ocular surface: a review. Exp Eye Res 2004;78:457-72.
8. Altinors DD, Bozbeyoglu S, Karabay G, et al. Evaluation of ocular surface changes in a rabbit dry eye model using a modified impression cytology technique. Curr Eye Res 2007;32:301-7. (Pubitemid 46633854)
9. Rolando M, Brezzo V, Calabria G. Ocular surface changes induced by repeated impression cytology. Adv Exp Med Biol 1994;350:249-54.
10. Kobayashi A, Yoshita T, Sugiyama K. In vivo laser and white light confocal microscopic findings of the human conjunctiva. Ophthalmic Surg Lasers Imaging 2004;35:482-4.
11. Messmer EM, Mackert MJ, Zapp DM, et al. In vivo confocal microscopy of normal conjunctiva and conjunctivitis. Cornea 2006;25:781-8.
12. Ciancaglini M, Carpineto P, Agnifili L, et al. An in vivo confocal microscopy and impression cytology analysis of preserved and unpreserved levobunolol-induced conjunctival changes. Eur J Ophthalmol 2008;18:400-7.
13. Amar N, Labbé A, Hamard P, et al. Filtering blebs and aqueous pathway an immunocytological and in vivo confocal microscopy study. Ophthalmology 2008;115:1154-61.
14. Vitali C, Bombardieri S, Jonsson R, et al. Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002;1:554-8.
15. Schiffman RM, Christianson MD, Jacobsen G, et al. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol 2000;118:615-21.
16. Li M, Zhang M, Lin Y, et al. Tear function and goblet cell density after pterygium excision. Eye 2007;21:224-8. (Pubitemid 46454602)
17. Kunert KS, Tisdale AS, Gipson IK. Goblet cell numbers and epithelial proliferation in the conjunctiva of patients with dry eye syndrome treated with cyclosporine. Arch Ophthalmol 2002;120:330-7.
18. Latkany R. Dry eyes: etiology and management. Curr Opin Ophthalmol 2008;19:287-91.
19. Nelson JD, Wright JC. Impression cytology of the ocular surface in keratoconjunctivitis sicca. In: Holly FJ, ed. The preocular tear film in health, disease, and contact lens wear. Lubbock: Texas Dry Eye Institute, 1986:140-56.
20. Wantanabe H. Significance of mucin on the ocular surface. Cornea 2002;21(Suppl 1):S17-22.
21. Murube J, Rivas L. Impression cytology on conjunctiva and cornea in dry eye patients establishes a correlation between squamous metaplasia and dry eye clinical severity. Eur J Ophthalmol 2003;13:115-27.
22. Wei ZG, Sun TT, Lavker RM. Rabbit conjunctival and corneal epithelial cells belong to two separate lineages. Invest ophthalmol Vis Sci 1996;37:523-33.
23. Stern ME, Gao J, Schwalb TA, et al. Conjunctival T-cell subpopulations in Sjogren's and non-Sjogren's patients with dry eye. Invest Ophthalmol Vis Sci 2002;43:2609-14. (Pubitemid 34809449)
24. Pflugfelder SC, De Paiva CS, Villarreal AL, et al. Effects of sequential artificial tear and cyclosporine emulsion therapy on conjunctival goblet cell density and transforming growth factor-B2 production. Cornea 2008;27:64-9.
25. Rivas L, Rodriguez JJ, Alvarez MI, et al. Correlation between impression cytology and tear function parameters in Sjögren's syndrome. Acta Ophthalmol 1993;71:353-9.
26. Ciancaglini M, Carpineto P, Agnifili L, et al. Conjunctival modifications in ocular hypertension and primary open angle glaucoma: an in vivo confocal microscopy study. Invest Ophthalmol Vis Sci 2008;49:3042-8.