Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells

Journal of Immunology

Volumn 185, Issue 9, 2010, Pages 5236-5246

  Ansa Addo, Ephraim A ^a   Lange, Sigrun ^b   Stratton, Dan ^a   Antwi Baffour, Samuel ^a   Cestari, Igor ^a,c,e   Ramirez, Marcel I ^a,c   McCrossan, Maria V ^d   Inal, Jameel M ^a  

^a LONDON METROPOLITAN UNIVERSITY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA1;

ACUTE MONOCYTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; CELL SURFACE; CELL VACUOLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS INHIBITION; MONOCYTE; PLASMA MEMBRANE DERIVED VESICLE; PRIORITY JOURNAL; APOPTOSIS; CELL SEPARATION; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CELL SEPARATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LEUKEMIA, MONOCYTIC, ACUTE; MICROSCOPY, ELECTRON, TRANSMISSION; MONOCYTES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 78149475085     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001656     Document Type: Article

References (43)

1. Simons, M., and G. Raposo. 2009. Exosomes: vesicular carriers for intercellular communication. Curr. Opin. Cell Biol. 21:575-581.
2. Hugel, B., M. C. Martínez, C. Kunzelmann, and J. M. Freyssinet. 2005. Membrane microparticles: two sides of the coin. Physiology (Bethesda) 20:22-27.
3. Ratajczak, J., M. Wysoczynski, F. Hayek, A. Janowska-Wieczorek, and M. Z. Ratajczak. 2006. Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia 20:1487-1495.
4. Hunter, M. P., N. Ismail, X. Zhang, B. D. Aguda, E. J. Lee, L. Yu, T. Xiao, J. Schafer, M. L. Lee, T. D. Schmittgen, et al. 2008. Detection of microRNA expression in human peripheral blood microvesicles. PLoS ONE 3: e3694.
5. Piccin, A., W. G. Murphy, and O. P. Smith. 2007. Circulating microparticles: pathophysiology and clinical implications. Blood Rev. 21:157-171.
6. Nickel, W. 2005. Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells. Traffic 6:607-614.
7. MacKenzie, A., H. L. Wilson, E. Kiss-Toth, S. K. Dower, R. A. North, and A. Surprenant. 2001. Rapid secretion of interleukin-1β by microvesicle shedding. Immunity 15:825-835.
8. Flieger, O., A. Engling, R. Bucala, H. Lue, W. Nickel, and J. Bernhagen. 2003. Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett. 551:78-86.
9. Gregory, J. L., E. F. Morand, S. J. McKeown, J. A. Ralph, P. Hall, Y. H. Yang, S. R. McColl, and M. J. Hickey. 2006. Macrophage migration inhibitory factor induces macrophage recruitment via CC chemokine ligand 2. J. Immunol. 177:8072-8079.
10. Abedin, M. J., Y. Kashio, M. Seki, K. Nakamura, and M. Hirashima. 2003. Potential roles of galectins in myeloid differentiation into three different lineages. J. Leukoc. Biol. 73:650-656.
11. Forrest, A. R. R., M. Kanamori-Katayama, Y. Tomaru, T. Lassmann, N. Ninomiya, Y. Takahashi, M. J. de Hoon, A. Kubosaki, A. Kaiho, M. Suzuki, et al. 2010. Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia 24:460-466.
12. Martínez, M. C., F. Larbret, F. Zobairi, J. Coulombe, N. Debili, W. Vainchenker, M. Ruat, and J.-M. Freyssinet. 2006. Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens. Blood 108:3012-3020.
13. Ratajczak, J., K. Miekus, M. Kucia, J. Zhang, R. Reca, P. Dvorak, and M. Z. Ratajczak. 2006. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia 20:847-856.
14. Eken, C., O. Gasser, G. Zenhaeusern, I. Oehri, C. Hess, and J. A. Schifferli. 2008. Polymorphonuclear neutrophil-derived ectosomes interfere with the maturation of monocyte-derived dendritic cells. J. Immunol. 180:817-824.
15. Garay, E., R. Donnelly, X. Wang, and G. P. Studzinski. 2007. Resistance to 1, 25D-induced differentiation in human acute myeloid leukemia HL60-40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor. J. Cell. Physiol. 213:816-825.
16. Champelovier, P., V. Pautre, M. Elatifi, I. Dupré, B. Rostaing, A. Michoud, F. Berger, and D. Seigneurin. 2006. Resistance to phorbol ester-induced differentiation in human myeloid leukemia cells: a hypothetic role for the mRNA stabilization process. Leuk. Res. 30:1407-1416.
17. Garcia, B. A., D. M. Smalley, H. Cho, J. Shabanowitz, K. Ley, and D. F. Hunt. 2005. The platelet microparticle proteome. J. Proteome Res. 4:1516-1521.
18. Li, M. O., Y. Y. Wan, S. Sanjabi, A.-K. L. Robertson, and R. A. Flavell. 2006. Transforming growth factor-β regulation of immune responses. Annu. Rev. Immunol. 24:99-146.
19. de Almeida, M. C., A. C. Silva, A. Barral, and M. Barral Netto. 2000. A simple method for human peripheral blood monocyte isolation. Mem. Inst. Oswaldo Cruz 95:221-223.
20. Sham, R. L., P. D. Phatak, K. A. Belanger, C. Braggins, and C. H. Packman. 1995. Functional characteristics of mature granulocytes in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid. Leuk. Res. 19:505-511.
21. Inal, J. M., K.-M. Hui, S. Miot, S. Lange, M. I. Ramirez, B. Schneider, G. Krueger, and J. A. Schifferli. 2005. Complement C2 receptor inhibitor trispanning: a novel human complement inhibitory receptor. J. Immunol. 174:356-366.
22. Morgan, B. P., and A. K. Campbell. 1985. The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium. Biochem. J. 231:205-208.
23. Kuypers, F. A., and K. de Jong. 2004. The role of phosphatidylserine in recognition and removal of erythrocytes. Cell. Mol. Biol. (Noisy-le-grand) 50:147-158.
24. Azevedo, L. C. P., M. Janiszewski, V. Pontieri, M. de. A. Pedro, E. Bassi, P. J. Tucci, and F. R. Laurindo. 2007. Platelet-derived exosomes from septic shock patients induce myocardial dysfunction. Crit. Care 11: R120.
25. Bombara, C., and R. A. Ignotz. 1992. TGF-β inhibits proliferation of and promotes differentiation of human promonocytic leukemia cells. J. Cell. Physiol. 153:30-37.
26. Turley, J. M., L. A. Falk, F. W. Ruscetti, J. J. Kasper, T. Francomano, T. Fu, O. S. Bang, and M. C. Birchenall-Roberts. 1996. Transforming growth factor β1 functions in monocytic differentiation of hematopoietic cells through autocrine and paracrine mechanisms. Cell Growth Differ. 7:1535-1544.
27. 3-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex. J. Exp. Med. 190:1583-1594.
28. Lehmann, L. E., S. U. Weber, D. Fuchs, S. Klaschik, J. C. Schewe, M. Book, A. Hoeft, and F. Stüber. 2005. Intracellular detection of macrophage migration inhibitory factor in peripheral blood leukocytes. Free Radic. Biol. Med. 38:1170-1179.
29. Mizukoshi, E., M. Suzuki, A. Loupatov, T. Uruno, H. Hayashi, T. Misono, S. C. Kaul, R. Wadhwa, and T. Imamura. 1999. Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin. Biochem. J. 343:461-466.
30. Liu, F. T. 2005. Regulatory roles of galectins in the immune response. Int. Arch. Allergy Immunol. 136:385-400.
31. Théry, C., M. Boussac, P. Véron, P. Ricciardi-Castagnoli, G. Raposo, J. Garin, and S. Amigorena. 2001. Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J. Immunol. 166:7309-7318.
32. Jenkins, G. 2008. The role of proteases in transforming growth factor-b activation. Int. J. Biochem. Cell Biol. 40:1068-1078.
33. Zhu, L., and A. I. Skoultchi. 2001. Coordinating cell proliferation and differentiation. Curr. Opin. Genet. Dev. 11:91-97.
34. Halder, S. K., R. D. Beauchamp, and P. K. Datta. 2005. A specific inhibitor of TGF-b receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia 7:509-521.
35. Pap, E., E. Pállinger, M. Pásztói, and A. Falus. 2009. Highlights of a new type of intercellular communication: microvesicle-based information transfer. Inflamm. Res. 58:1-8.
36. Del Conde, I., C. N. Shrimpton, P. Thiagarajan, and J. A. López. 2005. Tissuefactor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 106:1604-1611.
37. 2, and PAF. J. Clin. Invest. 101:890-898.
38. Gasser, O., and J. A. Schifferli. 2004. Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. Blood 104:2543-2548.
39. Al-Nedawi, K., B. Meehan, J. Micallef, V. Lhotak, L. May, A. Guha, and J. Rak. 2008. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat. Cell Biol. 10:619-624.
40. Wahl, S. M., and W. Chen. 2005. Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases. Arthritis Res. Ther. 7:62-68.
41. + regulatory T cells is mediated by cell surfacebound transforming growth factor β. J. Exp. Med. 194:629-644.
42. Baker, K., P. Raut, and J. R. Jass. 2008. Colorectal cancer cells express functional cell surface-bound TGFβ. Int. J. Cancer 122:1695-1700.
43. Yingling, J. M., K. L. Blanchard, and J. S. Sawyer. 2004. Development of TGF-β signalling inhibitors for cancer therapy. Nat. Rev. Drug Discov. 3:1011-1022.