Acid modulation of HT29 cell growth and differentiation. An in vitro model for Barrett's esophagus

Journal of Cell Science

Volumn 110, Issue 5, 1997, Pages 663-671

  Fitzgerald, Rebecca C ^a   Omary, M Bishr ^a   Triadafilopoulos, George ^a  

^a NONE

Author keywords

Barrett's esophagus; Microvilli; Na H exchanger (NHE); Villin

Indexed keywords

CYCLINE; VILLIN;

ARTICLE; BARRETT ESOPHAGUS; BRUSH BORDER; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HT29; HUMAN; HUMAN CELL; MICROVILLUS; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE;

BARRETT ESOPHAGUS; BLOOD; CELL DIFFERENTIATION; CELL DIVISION; HT29 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, BIOLOGICAL; SODIUM-HYDROGEN ANTIPORTER;

EID: 0030951685     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Barnard, J. A. and Warwick, G. (1993). Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ. 4, 495-501.
2. Beauregard, M. C. D., Pringault, E., Robine, S. and Louvard, D. (1995). Suppression of villin expression by antisense RNA on brush border assembly in polarized epithelial intestinal cells. EMBO J. 14, 409-421.
3. Boller, K., Arpin, M., Pringault, E. and Reggio, H. (1988). Differential distribution of villin and villin mRNA in mouse intestinal epithelial cells. Differentiation 39, 51-57.
4. Bretscher, A. and Weber, K. (1980). Villin is a major protein of microvillus cytoskeleton which binds G and F actin in a calcium-dependent manner. Cell 20, 839.
5. Bretscher, A., Osborn, A., Wehland, J. and Weber, K. (1981). Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin. Exp. Cell Res. 135, 213-219.
6. Colton, T. (1974). Statistics in medicine. Little. Brown and Company, Boston.
7. Cutz, E., Rhoads, J. M., Drumm, B., Shermann, P. M., Drurie, P. and Forstner, G. G. (1989). Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation. New Eng. J. Med. 320, 646-651.
8. Fath, K. R. and Burgess, D. R. (1995). Not actin alone. Curr. Biol. 5, 591-593.
9. Fischer, H. (1989). Malignancy may contribute to rapid evolution. Med. Hypoth. 28, 35-38.
10. Fitzgerald, R. C., Omary, M. B. and Triadafilopoulos, G. (1996). Dynamic effects of acid on Barrett's esophagus: an ex vivo differentiation and proliferation model. J. Clin. Invest. 98, 2, 2120-2128.
11. Forte, J. G. and Wolosin, J. M. (1987) In Physiology of the Gastrointestinaal Tract (ed. R. Johnson), Raven Press, New York.
12. Forte, J. G. and Xuebiao, Y. (1996). The membrane recruitment-and-recycling hypothesis of gastric HCl secretion. Trends Cell Biol. 6, 45-49.
13. Friederich, E., Huet, C., Arpin, M. and Louvard, D. (1989). Villin induces microvilli growth and actin redistribution in transfected fibroblasts. Cell 59, 461-475.
14. Friederich, E., Vancompernolle, K., Huet, C., Goethals, M., Finidon, J., Vandejerckhove, J. and Louvard, D. (1992). An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin. Cell 70, 81-92.
15. Gerson, D. F., Keifer, H. and Eufe, W. (1982). Intacellular pH of mitogen stimulated lymphocytes. Science 216, 1009-1010.
16. + exchanger. J. Membr. Biol. 90, 1-12.
17. Grinstein, S., Riotin, D. and Mason, M. J. (1989). Na/H exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim. Biophys. Acta 988, 73-97.
18. Heerdt, B. G., Houston, M. A. and Augenlicht, L. A. (1994). Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res. 54, 3288-3294.
19. Hertz, F., Schermer, A., Hawler, M. and Bogart, L. H. (1981). Alkaline phosphatase in HT-29, a human cancer cell line: influence of sodium butyrate and hyperosmolality. Arch. Biochem. Biophys. 210, 581-591.
20. Hoffman, E. K. and Simonsen, L. O. (1989). Membrane mechanisms in volume and pH regulation in vertebrate cells. Physiol. Rev. 69, 315-378.
21. Isfort, R. J., Cody, D. B., Asquith, T. N., Ridder, G. M., Stuard, S. B. and LeBoeuf, R. A. (1993). Induction of protein phosphorylation, protein synthesis, immediate early gene expression and cellular proliferation by intracellular pH modulation. Eur. J. Biochem. 231, 349-357.
22. Jankowski, J. and Dover, R. (1993). Cell proliferation, differentiation and cell death in epithelial cells of the esophagus: a critical review of biological markers and their applications to research and diagnosis. Gullet 3, 1-15.
23. Johnson, L. (1987) In Physiology of the Gastrointestinal Tract, Ch. 10 (ed. L. Johnson), pp. 301-333. Raven Press.
24. Kottgen, M., Leipziger, J., Fischer, K. G., Nitschke, R. and Hreger, R. (1994). pH regulation in HT29 colon carcinoma cells. Pflugers Arch (Germany) 428, 179-185.
25. Kraus, M., Severin, T. and Wolf, B. (1994). Relevance of microenvironmental pH for self-organized tumor growth and invasion. Anticancer Res. 14, 1573-1583.
26. Kumble, S., Omary, M. B., Fajardo, L. F. and Triadafilopoulos, G. (1996). Multifocal heterogeneity in villin and Ep-cam expression in Barrett's esophagus. Int. J. Cancer 66, 48-54.
27. Kumble, S., Omary, M. B., Cartwright, C. A. and Triadafilopoulos, G. (1997). Src activation in malignant and premalignant epithelia of Barrett's esophagus. Gastroenterology (in press).
28. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
29. Levine, D. S., Rubin, C. E., Reid, B. J. and Haggitt, R. (1989). Specialized metaplstic columnar epithelium in Barrett's esophagus: a comparative transmission electron microscopic study. Lab. Invest. 60, 418-432.
30. Lidofsky, S., Fitz, J. and Scharschmidt, B. (1994) In Progress in Liver Diseases (ed. H. Popper and F. Schaffner), pp. 69-83. Grune and Stratton, New York.
31. Lupton, J. R. and Kurtz, P. P. (1993). Relationship of colonie luminal short-chain fatty acids and pH to in vivo cell proliferation in rats. J. Nutr. 123, 1522-1530.
32. Madshus, I. H. (1988). Regulation of intracellular pH in eukaryotic cells. Biochem. J. 250, 1-8.
33. Martin, G. and Jain, R. (1994). Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Cancer Res. 54, 5670-5674.
34. Matsudaira, P. T. and Burgess, D. R. (1979). Identification and organization of the compartments of the isolated microvillus cytoskeleton. J. Cell Biol. 83, 667-673.
35. McDougall, C. J., Wong, R., Scudera, P., Lesser, M. and Cosse, J. J. D. (1993). Colonie mucosal pH in humans. Dig. Dis. Sci. 38, 542-545.
36. Moolenar, W. H. (1986). Effects of growth factors on intracellular pH regulation. Annu. Rev. Physiol. 48, 363-376.
37. Moolenar, W. H., Defize, L. H. K. and DeLaat, S. W. (1986). Ionic signaling by growth factor receptors. J. Exp. Biol. 124, 359-373.
38. Mooseker, M. S. (1985). Organization, chemistry and assembly of the cytoskeletal apparatus of the intestinal brush border. Annu. Rev. Cell Biol. 1, 209-241.
39. Ober, S. S. and Pardee, A. B. (1987). Intracellular pH is increased after transformation of chinese hamster embryo fibroblasts. Proc. Nat. Acad. Sci. USA 84, 2766-2770.
40. 1 events and regulation of cell proliferation. Science 246, 603-608.
41. Pettit, J. M., Driel, I. R. V., Ben-Hock, T. and Gleeson, P. A. (1996). From coiled tubules to a secretory canaliculus: a model for membrane transformation and acid secretion by gastric parietal cells. Trends Cell Biol. 6, 49-53.
42. Pinto, M., Appay, M. D., Simon-Assmann, P., Chevalier, G., Dracopoli, N., Fogh, J. and Zweibaum, A. (1982). Enterocytic differentiation of cultured human colon cancer cells by replacement of glucose by galactose in the medium. Biol. Cell 44, 193-196.
43. Pringault, E. M., Arpin, M., Garcia, A., Findori, A. and Louvard, D. A. (1986). Human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo. EMBO J. 5, 3119-3124.
44. Reid, B. J. (1991). Barrett's esophagus and esophageal adenocarcinoma. Gastroenterol. Clin. North Amer. 20, 817-834.
45. Rhoads, J. M., Cogler, R. C., Lacey, S. R., Reddick, R. L., Keku, E. O., Azizkhan, R. G. and Berschneider, H. M. (1991). Microvillus inclusion disease: in vitro electrolyte transport. Gastroenterology 100, 811-817.
46. Robine, S. C., Huet, R., Moll, R., C Sahuquillo-Merino, Coudrier, E., Zweibaum, A. and Louvard, D. (1985). Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells? Proc. Nat. Acad. Sci. 8, 8488-8492.
47. Rotin, D., Steele-Nirwood, D., Grinstein, S. and Tannock, I. (1989). Requirement of the Na/H exchanger for tumor growth. Cancer Res. 49, 205-211.
48. Shackney, S. and Shankey, T. (1995). Genetic and phenotypic heterogeneity of human malignancies: finding order in chaos. Cytometry 21, 2-5.
49. Shibayama, T., Carboni, J. M. and Mooseker, M. S. (1987). Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes. J. Cell Biol. 105, 335-344.
50. Silen, W. (1987) In Physiology of the Gastrointestinal Tract (ed. L. Johnson) pp. 1055-1069. Raven Press, New York.
51. - cotransport in rabbit kidney proximal tubules. J. Clin. Invest. 90, 211-218.
52. - cotransport in rabbit kidney proximal tubules. J. Lab. Clin. Med. 124, 69-78.
53. Soleimani, M. and Singh, G. (1995). Physiologic and molecular aspects of the Na/H exchangers in health and disease processes. J. Invest. Med. 43, 419-430.
54. Stidwill, R. P., Wysolmerski, T. and Burgess, D. R. (1984). The brush border cytoskeleton is not static: In vivo turnover of proteins. J. Cell Biol. 98, 641-645.
55. Tobey, N. A., Srighar, P. R., Keku, T. O., Jr, E. J. C. and Orlando, R. C. (1993). Mechanisms of HCl-induced lowering of intracellular pH on rabbit esophageal epithelial cells. Gastroenterology 105, 1035-1044.
56. Vaupel, P. (1996). Is there a critical tissue oxygen tension for bioenergetic status and cellular pH regulation in solid tumors. Experientia 52, 464-468.
57. Velazquez, O. C., Lederer, H. M. and Rombeau, J. L. (1996). Butyrate and the colonocyte. Dig. Dis. Sci. 41, 727-739.
58. White, M. W. (1992). Metabolism of the malignant cell, in vivo is anaerobic and plays a signiticantrole in the pathway to carcinogenesis. Med. Hypoth. 39, 323-333.
59. Zweibaum, A., Pinto, M., Chevalier, G., Dussaulx, E., Triadou, N., LaCroix, B., Haffen, K., Brun, J.-L. and Roussel, M. (1985). Enterocytic differentiation of a subpopulation of the human colon tumor line HT-29 selected for growth in sugar-free medium and its inhibition by glucose. J. Cell. Physiol. 122, 21-29.