Polymorphisms in MC4R gene and correlations with economic traits in cattle

Molecular Biology Reports

Volumn 37, Issue 8, 2010, Pages 3941-3944

  Huang, Meng ^a,b   Gao, Xue ^b   Li, Jun Ya ^b   Ren, Hong Yan ^b   Chen, Jin Bao ^b   Xu, Shang Zhong ^a,b  

^a NORTHWEST A F UNIVERSITY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Cattle; Marker assisted selection; MC4R; Meat trait; SNP

Indexed keywords

MELANOCORTIN 4 RECEPTOR;

ANIMAL TISSUE; ARTICLE; BODY FAT DISTRIBUTION; CATTLE; CONTROLLED STUDY; ECONOMIC ASPECT; EXON; FAT CONTENT; FOOD COMPOSITION; FOOD QUALITY; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC CORRELATION; GENETIC MARKER; GENETIC TRAIT; GENETIC VARIABILITY; LINKAGE ANALYSIS; LIPID STORAGE; LIVEWEIGHT GAIN; MEAT INDUSTRY; MISSENSE MUTATION; NONHUMAN; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS MAPPING; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; BREEDING; CATTLE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETICS, POPULATION; GENOTYPE; MEAT; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; RECEPTOR, MELANOCORTIN, TYPE 4;

BOS; SUIDAE;

EID: 78149467116     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0051-0     Document Type: Article

References (15)

1. C Vilo A Fernandez MC Rodrcguez M Nieto L Silis 2006 Association of mc4r gene variants with growth, fatness, carcass composition and meat and fat quality traits in heavy pigs Meat Sci 73 42 47 10.1016/j.meatsci.2005.10.016 (Pubitemid 43177743)
2. S Benoit M Schwartz D Baskin SC Woods RJ Seeley 2000 Cns melanocortin system involvement in the regulation of food intake Horm Behav 37 299 305 1:CAS:528:DC%2BD3cXksFOnsbw%3D 10.1006/hbeh.2000.1588 10860674 (Pubitemid 30432349)
3. A Haegeman F Coopman K Jacobs M Mattheeuws A van Zeveren L Peelman 2001 Bovine melanocortin receptor 4: cdna sequence, polymorphisms and mapping Anim Genet 32 189 192 1:CAS:528:DC%2BD3MXntFGqtb4%3D 10.1046/j.1365-2052.2001.00750.x 11531696 (Pubitemid 32818480)
4. TD Thue SM Schmutz FC Buchanan 2001 A snp in the cattle mc4r gene is used to map mc4r to bta 24 Anim Genet 32 390 391 1:CAS:528:DC%2BD38Xlt1yhug%3D%3D 10.1046/j.1365-2052.2001.0781b.x 11736813
5. R Jokubka S Maak S Kerziene HH Swalve 2006 Association of a melanocortin 4 receptor (mc4r) polymorphism with performance traits in Lithuanian white pigs J Anim Breed Genet 123 17 22 1:CAS:528:DC%2BD28XisFWqsrk%3D 10.1111/j.1439-0388. 2006.00559.x 16420261
6. RD Houston ND Cameron KA Rance 2004 A melanocortin-4 receptor (mc4r) polymorphism is associated with performance traits in divergently selected large white pig populations Anim Genet 35 386 390 1:CAS:528:DC%2BD2cXptFWjtrk%3D 10.1111/j.1365-2052.2004.01182.x 15373742 (Pubitemid 39333163)
7. KS Kim N Larsen T Short G Plastow MF Rothschild 2000 A missense variant of the porcine melanocortin-4 receptor (mc4r) gene is associated with fatness, growth, and feed intake traits Mamm Genome 11 131 135 1:CAS:528: DC%2BD3cXhtFOkur0%3D 10.1007/s003350010025 10656927 (Pubitemid 30054415)
8. M Stachowiak M Szydlowski M Obarzanek-Fojt M Switonski 2006 An effect of a missense mutation in the porcine melanocortin-4 receptor (mc4r) gene on production traits in Polish pig breeds is doubtful Anim Genet 37 55 57 1:CAS:528:DC%2BD28XitVCmsbw%3D 10.1111/j.1365-2052.2005.01373.x 16441297 (Pubitemid 43381854)
9. M Raymond F Rousset 1995 Genepop (version 1.2): population genetics software for exact tests and ecumenicism J Hered 86 248 249
10. YY Shi L He 2005 Shesis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci Cell Res 15 97 98 1:CAS:528:DC%2BD2MXksFynsro%3D 10.1038/sj.cr.7290286 15740637 (Pubitemid 41653943)
11. H Liu W Tian L Zan H Wang H Cui 2010 Mutations of mc4r gene and its association with economic traits in Qinchuan cattle Mol Biol Rep 37 535 540 1:CAS:528:DC%2BC3cXisFSltQ%3D%3D 10.1007/s11033-009-9706-0 19714485
12. CL Zhang YH Wang H Chen XY Lan CZ Lei XT Fang 2009 Association between variants in the 5′-untranslated region of the bovine mc4r gene and two growth traits in Nanyang cattle Mol Biol Rep 36 1839 1843 1:CAS:528: DC%2BD1MXptV2ntbk%3D 10.1007/s11033-008-9388-z 18987992
13. D Huszar CA Lynch V Fairchild-Huntress JH Dunmore Q Fang LR Berkemeier W Gu RA Kesterson BA Boston RD Cone FJ Smith LA Campfield P Burn F Lee 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice Cell 88 131 141 1:CAS:528:DyaK2sXltF2nsg%3D%3D 10.1016/S0092-8674(00)81865-6 9019399
14. AA Butler RA Kesterson K Khong MJ Cullen MA Pelleymounter J Dekoning M Baetscher RD Cone 2000 A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse Endocrinology 141 3518 3521 1:CAS:528:DC%2BD3cXmtVertL0%3D 10.1210/en.141.9.3518 10965927 (Pubitemid 32269044)
15. AS Chen DJ Marsh ME Trumbauer EG Frazier XM Guan H Yu CI Rosenblum A Vongs Y Feng L Cao JM Metzger AM Strack RE Camacho TN Mellin CN Nunes W Min J Fisher S Gopal-Truter DE MacIntyre HY Chen LH van der Ploeg 2000 Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass Nat Genet 26 97 102 1:CAS:528:DC%2BD3cXmsVKrsrw%3D 10.1038/79254 10973258