Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas

Brain Research

Volumn 1363, Issue , 2010, Pages 159-169

  Harley, William ^a   Floyd, Candace ^b   Dunn, Tamara ^a   Zhang, Xiao Dong ^a   Chen, Tsung Yu ^a   Hegde, Manu ^c   Palandoken, Hasan ^d   Nantz, Michael H ^e   Leon, Leonardo ^a   Carraway III, K L ^a   Lyeth, Bruce ^a   Gorin, Fredric A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

^e UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Hypoxic ischemic tumor microenvironment; Malignant glioma; Non apoptotic cell death; Sodium calcium exchanger; Sodium hydrogen exchanger

Indexed keywords

2 [4 (2,5 DIFLUOROBENZYLOXY)PHENOXY] 5 ETHOXYANILINE; 2',4' DICHLOROBENZAMIL; AMILORIDE; CALCIUM; CALCIUM IONOPHORE; CARIPORIDE; CASPASE; ION TRANSPORT AFFECTING AGENT; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CALCIUM TRANSPORT; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RAT;

AMILORIDE; ANILINE COMPOUNDS; ANIMALS; ASTROCYTES; BRAIN NEOPLASMS; CALCIUM; CELL DEATH; CELL LINE, TUMOR; CYTOSOL; GLIOMA; GUANIDINES; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; IONOMYCIN; IONOPHORES; PERSONAL SPACE; PHENYL ETHERS; PROTONS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM-CALCIUM EXCHANGER; SODIUM-HYDROGEN ANTIPORTER; SULFONES; TUMOR MICROENVIRONMENT;

EID: 78149465561     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.09.059     Document Type: Article

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