Whole blood transcriptomics in cardiac surgery identifies a gene regulatory network connecting ischemia reperfusion with systemic inflammation

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Liangos, Orfeas ^a   Domhan, Sophie ^a,b   Schwager, Christian ^b   Zeier, Martin ^b   Huber, Peter E ^b   Addabbo, Francesco ^c   Goligorsky, Michael S ^c   Hlatky, Lynn ^a   Jaber, Bertrand L ^a   Abdollahi, Amir ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 5; CALGRANULIN A; CALGRANULIN B; CCAAT ENHANCER BINDING PROTEIN BETA; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; PENTRAXIN 3; PHOSPHOGLYCERATE KINASE; RESISTIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; PLASMA PROTEIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; HEART MUSCLE ISCHEMIA; HEART SURGERY; HUMAN; MALE; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; REPERFUSION INJURY; RNA ISOLATION; TRANSCRIPTOMICS; UPREGULATION; BLOOD; GENETICS; PROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THORAX SURGERY;

BLOOD PROTEINS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; PROSPECTIVE STUDIES; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THORACIC SURGICAL PROCEDURES;

EID: 78149455122     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013658     Document Type: Article

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