Efficient one-pot synthesis of spirooxindole derivatives containing 1,4-dihydropyridine-fused-1,3-diazaheterocycle fragments via four-component reaction

Synthesis

Volumn , Issue 22, 2010, Pages 3913-3917

  Alizadeh, Abdolali ^a   Firuzyar, Tahereh ^a   Mikaeili, Azadeh ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

1,1 bis(methylthio) 2 nitroethylene; 1,4 dihydropyridine; 1,n diamine; malononitrile; multicomponent reaction; spirooxindole

Indexed keywords

1,4-DIHYDROPYRIDINE; 1,N-DIAMINE; MALONONITRILES; MULTI-COMPONENT REACTIONS; NITROETHYLENE; SPIROOXINDOLE;

ETHANOL; PYRIDINE;

SYNTHESIS (CHEMICAL);

5 AMINO 5' BROMO 8 NITRO 2' OXO 2,3 DIHYDRO 1H SPIRO(IMIDAZO[1,2 A]PYRIDINE 7,3' INDOLINE) 6 CARBONITRILE; 5 AMINO 8 NITRO 2' OXO 2,3 DIHYDRO 1H SPIRO(IMIDAZO[1,2 A]PYRIDINE 7,3' INDOLINE) 6 CARBONITRILE; 6' AMINO 3',3' DIMETHYL 5,9' DINITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; 6' AMINO 3',3' DIMETHYL 9' NITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; 6' AMINO 5 BROMO 3',3' DIMETHYL 9' NITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; 6' AMINO 5 BROMO 9' NITRO 2 OXO 1',2',3',4' TETRAHYDROSPIRO(INDOLINE 3,8' PYRIDO[1,2 A]PYRIMIDINE) 7' CARBONITRILE; 6' AMINO 5,9' DINITRO 2 OXO 1',2',3',4' TETRAHYDROSPIRO(INDOLINE 3,8' PYRIDO[1,2 A]PYRIMIDINE) 7' CARBONITRILE; 6' AMINO 9' DINITRO 2 OXO 1',2',3',4' TETRAHYDROSPIRO(INDOLINE 3,8' PYRIDO[1,2 A]PYRIMIDINE) 7' CARBONITRILE; 7' AMINO 10' NITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; 7' AMINO 5 BROMO 10' NITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; 7' AMINO 5,10' DINITRO 2 OXO 2',3',4',5' TETRAHYDRO 1'H SPIRO(INDOLINE 3,9' PYRIDO[1,2 A][1,3]DIAZEPINE) 8' CARBONITRILE; ALCOHOL; ISATIN; ISATIN DERIVATIVE; MALONONITRILE; OXINDOLE; PIPERIDINE; SPIROOXINDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CHEMICAL REACTION KINETICS; DRUG STRUCTURE; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

EID: 78149433944     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258249     Document Type: Article

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