Naked RNA vaccine controls tumors with down-regulated MHC class I expression through NK cells and perforin-dependent pathways

European Journal of Immunology

Volumn 34, Issue 7, 2004, Pages 1892-1900

  Cheng, Wen Fang ^a   Hung, Chien Fu ^b   Lee, Chien Nan ^a   Su, Yi Ning ^a   Chang, Ming Cheng ^a   He, Liangmei ^b   Wu, T C ^b   Chen, Chi An ^a   Hsieh, Chang Yao ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

HPV; Naked RNA replicon vaccine; NK cells; Tumor evasion; Tumor with down regulated MHC class I expression

Indexed keywords

CANCER VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; PERFORIN; POLYINOSINIC POLYCYTIDYLIC ACID; VIRUS PROTEIN; VIRUS VECTOR; HLA ANTIGEN CLASS 1; LYMPHOKINE; MEMBRANE PROTEIN; PORE FORMING CYTOTOXIC PROTEIN; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CONTROL; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DOWN REGULATION; DRUG DESIGN; FEMALE; GROWTH INHIBITION; HERPES SIMPLEX VIRUS 1; IN VIVO STUDY; LYMPHOCYTE SUBPOPULATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REPLICON; SINDBIS VIRUS; TUMOR CELL; TUMOR GROWTH; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; CYTOLOGY; CYTOTOXIC T LYMPHOCYTE; DRUG EFFECT; GENETICS; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; NEOPLASM; PATHOLOGY; TRANSPLANTATION; VACCINATION;

ADOPTIVE TRANSFER; ANIMALS; CANCER VACCINES; DOWN-REGULATION; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; LYMPHOCYTE SUBSETS; LYMPHOKINES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NEOPLASMS; POLY I-C; PORE FORMING CYTOTOXIC PROTEINS; RNA; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION;

EID: 3442875581     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200424877     Document Type: Article

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